Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Sohvi, Hörkkö"'
Autor:
Signe Abitz Winther, Miia Maininki Mannerla, Marie Frimodt-Møller, Frederik Persson, Tine Willum Hansen, Markku Lehto, Sohvi Hörkkö, Michael Blaut, Carol Forsblom, Per-Henrik Groop, Peter Rossing
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Gastrointestinal dysbiosis is common among persons with type 1 diabetes (T1D), but its potential impact on diabetic nephropathy (DN) remains obscure. We examined whether faecal biomarkers, previously associated with low-grade gastrointestina
Externí odkaz:
https://doaj.org/article/408992ee5356447c8bc81c5b73641639
Autor:
Satu Wedenoja, Aki Saarikivi, Jani Mälkönen, Saara Leskinen, Markku Lehto, Krishna Adeshara, Jetta Tuokkola, Anne Nikkonen, Laura Merras-Salmio, Miikka Höyhtyä, Sohvi Hörkkö, Anu Haaramo, Anne Salonen, Willem M de Vos, Katri Korpela, Kaija-Leena Kolho
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269561 (2022)
Background and aimsSubjects with congenital chloride diarrhea (CLD; a defect in solute carrier family 26 member 3 (SLC26A3)) are prone to inflammatory bowel disease (IBD). We investigated fecal microbiota in CLD and CLD-associated IBD. We also tested
Externí odkaz:
https://doaj.org/article/ecbd272b12df4bbbbf096ff751597a56
Autor:
Elisa Kopra, Laura Lahdentausta, Milla Pietiäinen, Kåre Buhlin, Päivi Mäntylä, Sohvi Hörkkö, Rutger Persson, Susanna Paju, Juha Sinisalo, Aino Salminen, Pirkko J. Pussinen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The use of systemic antibiotics may influence the oral microbiota composition. Our aim was to investigate in this retrospective study whether the use of prescribed antibiotics associate with periodontal status, oral microbiota, and antibodies against
Externí odkaz:
https://doaj.org/article/bdc374db8ad04e85aae3656c17a47882
Autor:
Mikael Kyrklund, Heidi Kaski, Ramin Akhi, Antti E Nissinen, Outi Kummu, Ulrich Bergmann, Pirkko Pussinen, Sohvi Hörkkö, Chunguang Wang
Publikováno v:
Innate Immunity, Vol 27 (2021)
Natural Abs are produced by B lymphocytes in the absence of external Ag stimulation. They recognise self, altered self and foreign Ags, comprising an important first-line defence against invading pathogens and serving as innate recognition receptors
Externí odkaz:
https://doaj.org/article/508fb681b9184c3cbaf3429d895e586b
Autor:
Mikael Kyrklund, Mika Bildo, Ramin Akhi, Antti E Nissinen, Pirkko Pussinen, Sohvi Hörkkö, Chunguang Wang
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230682 (2020)
Atherosclerosis is a chronic inflammatory disease and major cause of mortality worldwide. One of the crucial steps for atherosclerotic plaque development is oxidation of low-density lipoprotein (LDL). Through the oxidation, highly immunogenic epitope
Externí odkaz:
https://doaj.org/article/95388955764c4c1993e5bc4348a88f60
Autor:
Anniina Pirttiniemi, Krishna Adeshara, Natalie Happonen, Elisabet Einarsdottir, Shintaro Katayama, Hanne Salmenkari, Sohvi Hörkkö, Juha Kere, Per-Henrik Groop, Markku Lehto
Publikováno v:
Journal of Leukocyte Biology.
Inorganic polyphosphates are evolutionarily conserved bioactive phosphate polymers found as various chain lengths in all living organisms. In mammals, polyphosphates play a vital role in the regulation of cellular metabolism, coagulation, and inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb47faced062998865b1c47296cf061c
https://doi.org/10.1093/jleuko/qiad058
https://doi.org/10.1093/jleuko/qiad058
Autor:
Joonas Liukkonen, Ulvi K. Gürsoy, Eija Könönen, Ramin Akhi, Aino Salminen, John M. Liljestrand, Pratikshya Pradhan-Palikhe, Milla Pietiäinen, Timo Sorsa, G. Rutger Persson, Päivi Mäntylä, Kåre Buhlin, Susanna Paju, Juha Sinisalo, Sohvi Hörkkö, Pirkko J. Pussinen
Publikováno v:
Diagnostics, Vol 10, Iss 8, p 560 (2020)
The cumulative risk score (CRS) is a mathematical salivary diagnostic model to define an individual’s risk of having periodontitis. In order to further validate this salivary biomarker, we investigated how periodontal bacteria, lipopolysaccharide (
Externí odkaz:
https://doaj.org/article/9352fc96fe4a47879da47ad065602e0c
Autor:
Mikael Kyrklund, Outi Kummu, Jari Kankaanpää, Ramin Akhi, Antti Nissinen, S Pauliina Turunen, Pirkko Pussinen, Chunguang Wang, Sohvi Hörkkö
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191216 (2018)
Treatment of periodontitis has beneficial effects on systemic inflammation markers that relate to progression of atherosclerosis. We aimed to investigate whether immunization with A hemagglutinin domain (Rgp44) of Porphyromonas gingivalis (Pg), a maj
Externí odkaz:
https://doaj.org/article/0ac9ad104d71435f87211a55d554afef
Autor:
Dimitrios Tsiantoulas, Thomas Perkmann, Taras Afonyushkin, Andreas Mangold, Thomas A. Prohaska, Nikolina Papac-Milicevic, Vincent Millischer, Caroline Bartel, Sohvi Hörkkö, Chantal M. Boulanger, Sotirios Tsimikas, Michael B. Fischer, Joseph L. Witztum, Irene M. Lang, Christoph J. Binder
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 440-448 (2015)
Oxidation-specific epitopes (OSEs) present on apoptotic cells and oxidized low density lipoprotein (OxLDL) represent danger-associated molecular patterns that are recognized by different arcs of innate immunity, including natural IgM antibodies. Here
Externí odkaz:
https://doaj.org/article/3716a646b8944c4283de81d5bdef220c
Autor:
Natalie Istomin, Mari‐Anne Härma, Ramin Akhi, Antti E. Nissinen, Markku J. Savolainen, Krishna Adeshara, Markku Lehto, Per‐Henrik Groop, Vesa Koivukangas, Janne Hukkanen, Sohvi Hörkkö
Obesity is associated with low-grade inflammation and increased systemic oxidative stress. Roux-en-Y gastric bypass (RYGB) surgery is known to ameliorate the obesity-induced metabolic dysfunctions. We aimed to study the levels of natural antibodies i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5a81a34f3210035654bc34de32eb39
http://hdl.handle.net/10138/350368
http://hdl.handle.net/10138/350368
