Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sohui T. Won"'
Autor:
Benjamin O. Fulton, David Sachs, Shannon M. Beaty, Sohui T. Won, Benhur Lee, Peter Palese, Nicholas S. Heaton
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1331-1338 (2015)
Measles virus undergoes error-prone replication like other RNA viruses, but over time, it has remained antigenically monotypic. The constraints on the virus that prevent the emergence of antigenic variants are unclear. As a first step in understandin
Externí odkaz:
https://doaj.org/article/572093e3f28746d19e5c05d542a4dbdd
Autor:
Shannon M. Beaty, Arnold Park, Sohui T. Won, Patrick Hong, Michael Lyons, Frederic Vigant, Alexander N. Freiberg, Benjamin R. tenOever, W. Paul Duprex, Benhur Lee
Publikováno v:
mSphere, Vol 2, Iss 2 (2017)
ABSTRACT The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome th
Externí odkaz:
https://doaj.org/article/9ed5da7edaf44f2b8d23894e3de833c7
Autor:
Steffen Stenger, Robert L. Modlin, Lewis L. Lanier, David I. Weiss, Samuel J. Balin, Sohui T. Won, Barry R. Bloom, Jing Lu, Matteo Pellegrini, Aaron Choi, Maria Teresa Ochoa, Joshua K. Hakimian, Eynav Klechevsky
Publikováno v:
Science immunology, vol 3, iss 26
Human CD8(+) cytotoxic T lymphocytes (CTLs) contribute to antimicrobial defense against intracellular pathogens through secretion of cytotoxic granule proteins granzyme B, perforin, and granulysin. However, CTLs are heterogeneous in the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac96f805ca631c86932851abeac1e666
https://escholarship.org/uc/item/6vq1s5q9
https://escholarship.org/uc/item/6vq1s5q9
Autor:
Frederic Vigant, Benhur Lee, Arnold Park, Tatyana Yun, Sohui T. Won, Wojciech Bartkowski, Olivier Pernet, Brian E. Dawes, Alexander N. Freiberg
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005659 (2016)
PLoS pathogens, vol 12, iss 5
PLoS Pathogens
PLoS pathogens, vol 12, iss 5
PLoS Pathogens
The budding of Nipah virus, a deadly member of the Henipavirus genus within the Paramyxoviridae, has been thought to be independent of the host ESCRT pathway, which is critical for the budding of many enveloped viruses. This conclusion was based on t
Autor:
Kasopefoluwa Y. Oguntuyo, Justin Taft, Patricia A. Thibault, Benhur Lee, Frederic Vigant, Patrick Hong, Arnold Park, Sohui T. Won
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
The advent of RNA-guided endonuclease (RGEN)-mediated gene editing, specifically via CRISPR/Cas9, has spurred intensive efforts to improve the efficiency of both RGEN delivery and targeted mutagenesis. The major viral vectors in use for delivery of C
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95101 (2014)
PLoS ONE
PLoS ONE
Although modulation of protein levels is an important tool for study of protein function, it is difficult or impossible to knockdown or knockout genes that are critical for cell growth or viability. For such genes, a conditional knockdown approach wo
Autor:
Arnold Park, Tatyana Yun, Frederic Vigant, Olivier Pernet, Sohui T Won, Brian E Dawes, Wojciech Bartkowski, Alexander N Freiberg, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005659 (2016)
The budding of Nipah virus, a deadly member of the Henipavirus genus within the Paramyxoviridae, has been thought to be independent of the host ESCRT pathway, which is critical for the budding of many enveloped viruses. This conclusion was based on t
Externí odkaz:
https://doaj.org/article/bfbaab4065724a789412a8a68380ffcd
Autor:
Arnold Park, Patrick Hong, Sohui T Won, Patricia A Thibault, Frederic Vigant, Kasopefoluwa Y Oguntuyo, Justin D Taft, Benhur Lee
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
The advent of RNA-guided endonuclease (RGEN)-mediated gene editing, specifically via CRISPR/Cas9, has spurred intensive efforts to improve the efficiency of both RGEN delivery and targeted mutagenesis. The major viral vectors in use for delivery of C
Externí odkaz:
https://doaj.org/article/a47e9ef0babb4529a61546002c818f9a
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95101 (2014)
Although modulation of protein levels is an important tool for study of protein function, it is difficult or impossible to knockdown or knockout genes that are critical for cell growth or viability. For such genes, a conditional knockdown approach wo
Externí odkaz:
https://doaj.org/article/761a8b9f97be4e209a57f2fac44e88f9