Zobrazeno 1 - 10 of 45 pro vyhledávání: '"Sohshi Morimura"'
1
Akademický článek
Whole-Exome Sequencing Revealed a Pathogenic Germline Variant in the Fumarate Hydratase Gene, Leading to the Diagnosis of Hereditary Leiomyomatosis and Renal Cell Cancer
Autor: Akari Nagashima, Sohshi Morimura, Toshihisa Hamada, Takayuki Shiomi, Ichiro Mori, Naoko Sato, Junko Nomoto, Masaki Tanaka, Shoji Tsuji, Makoto Sugaya
Publikováno v: Diagnostics, Vol 14, Iss 12, p 1279 (2024)
The diagnosis of hereditary skin tumors is difficult for “old” diagnostic tools such as immunohistochemistry. Whole-exome sequencing analysis as a “new” diagnostic tool enables us to make a final diagnosis in spite of unknown hereditary disea
Externí odkaz: https://doaj.org/article/251012c66053417d8b68ed443d382c82
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2
Akademický článek
Secondary Malignant Tumors Arising in Nevus Sebaceus: Two Case Reports
Autor: Sohshi Morimura, Yasuhiko Tomita, Shinichi Ansai, Makoto Sugaya
Publikováno v: Diagnostics, Vol 12, Iss 6, p 1448 (2022)
Nevus sebaceus is a benign tumor that is present at birth and is often seen on the scalp or face. Secondary malignant tumors sometimes occur in nevus sebaceus in adulthood. Herein, we present two malignant tumors arose from nevus sebaceus. One is bas
Externí odkaz: https://doaj.org/article/c26accc061654b0c93c105c080695d3e
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3
Akademický článek
EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase
Autor: Takeshi Ouchi, Sohshi Morimura, Lukas E. Dow, Hiroyuki Miyoshi, Mark C. Udey
Publikováno v: Cells, Vol 10, Iss 2, p 256 (2021)
Humans with biallelic inactivating mutations in Epithelial Cell Adhesion Molecule (EpCAM) develop congenital tufting enteropathy (CTE). To gain mechanistic insights regarding EpCAM function in this disorder, we prepared intestinal epithelial cell (IE
Externí odkaz: https://doaj.org/article/66acaa9e1e6642ef89a9a820d9ab6d46
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4
Akademický článek
Amelioration of Congenital Tufting Enteropathy in EpCAM (TROP1)-Deficient Mice via Heterotopic Expression of TROP2 in Intestinal Epithelial Cells
Autor: Gaku Nakato, Sohshi Morimura, Michael Lu, Xu Feng, Chuanjin Wu, Mark C. Udey
Publikováno v: Cells, Vol 9, Iss 8, p 1847 (2020)
TROP1 (EpCAM) and TROP2 are homologous cell surface proteins that are widely expressed, and often co-expressed, in developing and adult epithelia. Various functions have been ascribed to EpCAM and TROP2, but responsible mechanisms are incompletely ch
Externí odkaz: https://doaj.org/article/3888e9b9a4a94c349a43084cb5bdbf22
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7
Increased Regulatory T Cells and Decreased Myeloid-Derived Suppressor Cells Induced by High CCL17 Levels May Account for Normal Incidence of Cancers among Patients with Atopic Dermatitis
Autor: Tomomitsu Miyagaki, Tomonori Oka, Yoshihide Asano, Yuichiro Tsunemi, Sohshi Morimura, Hiraku Suga, Shinichi Sato, Makoto Sugaya
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 2025, p 2025 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
The incidence of cancers in atopic dermatitis (AD) is not increased, although the Th2-dominant environment is known to downregulate tumor immunity. To gain mechanistic insights regarding tumor immunity in AD, we utilized CCL17 transgenic (TG) mice ov
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca14aa4ee8fea8e9e8a2f3702c6364f7
https://www.mdpi.com/1422-0067/22/4/2025
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8
EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase
Autor: Lukas E. Dow, Sohshi Morimura, Hiroyuki Miyoshi, Mark C. Udey, Takeshi Ouchi
Publikováno v: Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 256, p 256 (2021)
Humans with biallelic inactivating mutations in Epithelial Cell Adhesion Molecule (EpCAM) develop congenital tufting enteropathy (CTE). To gain mechanistic insights regarding EpCAM function in this disorder, we prepared intestinal epithelial cell (IE
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70320fa7f32bf62040316da9b1ddefe
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10
TLR2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation through Decrease in Regulatory T Cells and Impaired IL-10 Production
Autor: Sohshi Morimura, Makoto Sugaya, Shinichi Sato, Yoshihide Asano, Hideki Fujita, Momoko Nakao, Tomomitsu Miyagaki, Sayaka Shibata
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8560, p 8560 (2020)
Emerging evidence has demonstrated that Toll-like receptors (TLRs) are associated with autoimmune diseases. In this study, we investigated the role of TLR2 in psoriasis using imiquimod-induced psoriasis-like dermatitis. Although TLR2 signaling is kno
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f92d90012b6879d537eb02c1311c071
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