Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sohrab, Salehi"'
Autor:
Adam C. Weiner, Marc J. Williams, Hongyu Shi, Ignacio Vázquez-García, Sohrab Salehi, Nicole Rusk, Samuel Aparicio, Sohrab P. Shah, Andrew McPherson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Dysregulated DNA replication is a cause and a consequence of aneuploidy in cancer, yet the interplay between copy number alterations (CNAs), replication timing (RT) and cell cycle dynamics remain understudied in aneuploid tumors. We develope
Externí odkaz:
https://doaj.org/article/1b0be3befa714b019d8233946a8926db
Autor:
Alvaro Quintanal-Villalonga, Kenta Kawasaki, Esther Redin, Fathema Uddin, Swanand Rakhade, Vidushi Durani, Amin Sabet, Moniquetta Shafer, Wouter R. Karthaus, Samir Zaidi, Yingqian A. Zhan, Parvathy Manoj, Harsha Sridhar, Dennis Kinyua, Hong Zhong, Barbara P. Mello, Metamia Ciampricotti, Umesh K. Bhanot, Irina Linkov, Juan Qiu, Radhika A. Patel, Colm Morrissey, Sanjoy Mehta, Jesse Barnes, Michael C. Haffner, Nicholas D. Socci, Richard P. Koche, Elisa de Stanchina, Sonia Molina-Pinelo, Sohrab Salehi, Helena A. Yu, Joseph M. Chan, Charles M. Rudin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Neuroendocrine (NE) transformation is a mechanism of resistance to targeted therapy in lung and prostate adenocarcinomas leading to poor prognosis. Up to date, even if patients at high risk of transformation can be identified by the occurren
Externí odkaz:
https://doaj.org/article/501fe4c8a5e9423ca573e0d9f455d0b2
Autor:
Farhia Kabeer, Hoa Tran, Mirela Andronescu, Gurdeep Singh, Hakwoo Lee, Sohrab Salehi, Beixi Wang, Justina Biele, Jazmine Brimhall, David Gee, Viviana Cerda, Ciara O’Flanagan, Teresa Algara, Takako Kono, Sean Beatty, Elena Zaikova, Daniel Lai, Eric Lee, Richard Moore, Andrew J. Mungall, IMAXT Consortium, Marc J. Williams, Andrew Roth, Kieran R. Campbell, Sohrab P. Shah, Samuel Aparicio
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-32 (2024)
Abstract Background The encoding of cell intrinsic drug resistance states in breast cancer reflects the contributions of genomic and non-genomic variations and requires accurate estimation of clonal fitness from co-measurement of transcriptomic and g
Externí odkaz:
https://doaj.org/article/49d08f6904d04bb2b5f01bd4a5faa66b
Autor:
Nicholas Ceglia, Zachary Sethna, Samuel S. Freeman, Florian Uhlitz, Viktoria Bojilova, Nicole Rusk, Bharat Burman, Andrew Chow, Sohrab Salehi, Farhia Kabeer, Samuel Aparicio, Benjamin D. Greenbaum, Sohrab P. Shah, Andrew McPherson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Deciphering individual cell phenotypes from cell-specific transcriptional processes requires high dimensional single cell RNA sequencing. However, current dimensionality reduction methods aggregate sparse gene information across cells, witho
Externí odkaz:
https://doaj.org/article/65a4f5b8f80d4f96bdbe1ea6e37f565d
Autor:
Peter Eirew, Ciara O’Flanagan, Jerome Ting, Sohrab Salehi, Jazmine Brimhall, Beixi Wang, Justina Biele, Teresa Algara, So Ra Lee, Corey Hoang, Damian Yap, Steven McKinney, Cherie Bates, Esther Kong, Daniel Lai, Sean Beatty, Mirela Andronescu, Elena Zaikova, Tyler Funnell, Nicholas Ceglia, Stephen Chia, Karen Gelmon, Colin Mar, Sohrab Shah, Andrew Roth, Alexandre Bouchard-Côté, Samuel Aparicio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Gene fitness and essentiality analyses using in vivo cancer models are challenging due to multiple confounders. Here, the authors develop a quantitative approach to study CRISPR-transduced patient-derived xenografts, which they use to analyse in vivo
Externí odkaz:
https://doaj.org/article/5fd8470d7bc644e19c6718168d7a7669
Autor:
Ali Akbar Karami, Amir Javadi, Sohrab Salehi, Neda Nasirian, Amirhosein Maali, Maryam Bakhshalizadeh Shadkam, Masoumeh Najari, Zahra Rousta, Safar Ali Alizadeh
Publikováno v:
Iranian Journal of Microbiology, Vol 14, Iss 2 (2022)
Background and Objectives: Prostatitis affects about 16% of men in their lifetime and sometimes leading to prostate cancer. Bacterial infections are the most common causes of prostatitis. Diagnosis of the causative agents of bacterial prostate infect
Externí odkaz:
https://doaj.org/article/45b69a23db46408484200211c9540997
Autor:
Roohollah Noori, Behzad Ghiasi, Sohrab Salehi, Mehdi Esmaeili Bidhendi, Amin Raeisi, Sadegh Partani, Rojin Meysami, Mehran Mahdian, Majid Hosseinzadeh, Soroush Abolfathi
Publikováno v:
Hydrology, Vol 9, Iss 2, p 36 (2022)
Sediment load in fluvial systems is one of the critical factors shaping the river geomorphological and hydraulic characteristics. A detailed understanding of the total sediment load (TSL) is required for the protection of physical, environmental, and
Externí odkaz:
https://doaj.org/article/138c1e6e3cb741dfa945d34c7d788ca0
Autor:
Nicholas Ceglia, Zachary Sethna, Samuel S. Freeman, Florian Uhlitz, Viktoria Bojilova, Nicole Rusk, Bharat Burman, Andrew Chow, Sohrab Salehi, Farhia Kabeer, Samuel Aparicio, Benjamin Greenbaum, Sohrab P. Shah, Andrew McPherson
Deciphering individual cell phenotypes from cell-specific transcriptional processes requires high dimensional single cell RNA sequencing. However, current dimensionality reduction methods aggregate sparse gene information across cells, without direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb930e748759dbadb3ef042822bdbe4f
https://doi.org/10.1101/2022.04.22.487554
https://doi.org/10.1101/2022.04.22.487554
Autor:
Abdollah Dargahi, Esmail Ghahramani, Sohrab Salehi, Hasan Zolghadr Nasab, Mohammad Reza Samarghandi
Publikováno v:
Water Environment Research. 92:1173-1183
Azo dyes are mostly toxic and carcinogenic and cause harm to humans and the environment. This study was conducted to investigate the degradation of azo dye acid red 14 (AR14) from aqueous solution using hydrogen peroxide (H2 O2) /nano zerovalent iron
Autor:
Tyler, Funnell, Ciara H, O'Flanagan, Marc J, Williams, Andrew, McPherson, Steven, McKinney, Farhia, Kabeer, Hakwoo, Lee, Sohrab, Salehi, Ignacio, Vázquez-García, Hongyu, Shi, Emily, Leventhal, Tehmina, Masud, Peter, Eirew, Damian, Yap, Allen W, Zhang, Jamie L P, Lim, Beixi, Wang, Jazmine, Brimhall, Justina, Biele, Jerome, Ting, Vinci, Au, Michael, Van Vliet, Yi Fei, Liu, Sean, Beatty, Daniel, Lai, Jenifer, Pham, Diljot, Grewal, Douglas, Abrams, Eliyahu, Havasov, Samantha, Leung, Viktoria, Bojilova, Richard A, Moore, Nicole, Rusk, Florian, Uhlitz, Nicholas, Ceglia, Adam C, Weiner, Elena, Zaikova, J Maxwell, Douglas, Dmitriy, Zamarin, Britta, Weigelt, Sarah H, Kim, Arnaud, Da Cruz Paula, Jorge S, Reis-Filho, Spencer D, Martin, Yangguang, Li, Hong, Xu, Teresa Ruiz, de Algara, So Ra, Lee, Viviana Cerda, Llanos, David G, Huntsman, Jessica N, McAlpine, Sohrab P, Shah, Pu, Zheng
Publikováno v:
Nature. 612(7938)
How cell-to-cell copy number alterations that underpin genomic instability