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A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses.

Autor: Vishwanath S; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Carnell GW; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Ferrari M; DIOSynVax Ltd, University of Cambridge, Cambridge, UK., Asbach B; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Billmeier M; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., George C; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Sans MS; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Nadesalingam A; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Huang CQ; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Paloniemi M; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Stewart H; Department of Pathology, University of Cambridge, Cambridge, UK., Chan A; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Wells DA; DIOSynVax Ltd, University of Cambridge, Cambridge, UK., Neckermann P; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Peterhoff D; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Einhauser S; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Cantoni D; Viral Pseudotype Unit, Medway School of Pharmacy, The Universities of Kent and Greenwich at Medway, Chatham, UK., Neto MM; Viral Pseudotype Unit, Medway School of Pharmacy, The Universities of Kent and Greenwich at Medway, Chatham, UK., Jordan I; ProBioGenAG, Berlin, Germany., Sandig V; ProBioGenAG, Berlin, Germany., Tonks P; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, The Universities of Kent and Greenwich at Medway, Chatham, UK., Frost S; DIOSynVax Ltd, University of Cambridge, Cambridge, UK.; London School of Hygiene and Tropical Medicine, London, UK.; Microsoft Health Futures, Redmond, WA, USA., Sohr K; Ethris GmbH, Planegg, Germany., Ballesteros MTL; Ethris GmbH, Planegg, Germany., Arbabi F; Ethris GmbH, Planegg, Germany., Geiger J; Ethris GmbH, Planegg, Germany., Dohmen C; Ethris GmbH, Planegg, Germany., Plank C; Ethris GmbH, Planegg, Germany., Kinsley R; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.; DIOSynVax Ltd, University of Cambridge, Cambridge, UK., Wagner R; DIOSynVax Ltd, University of Cambridge, Cambridge, UK.; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Heeney JL; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK. jlh66@cam.ac.uk.; DIOSynVax Ltd, University of Cambridge, Cambridge, UK. jlh66@cam.ac.uk.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2023 Sep 25. Date of Electronic Publication: 2023 Sep 25.

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