Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Soheila Dolatabadi"'
Autor:
Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Myxoid liposarcoma (MLS) displays a distinctive tumor microenvironment and is characterized by the FUS::DDIT3 fusion oncogene, however, the precise functional contributions of these two elements remain enigmatic in tumor developme
Externí odkaz:
https://doaj.org/article/efac96b56a16441ab22d151be2064aa6
Autor:
Soheila Dolatabadi, Emma Jonasson, Lisa Andersson, Manuel Luna Santamaría, Malin Lindén, Tobias Österlund, Pierre Åman, Anders Ståhlberg
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Myxoid liposarcoma is one of the most common sarcoma entities characterized by FET fusion oncogenes. Despite a generally favorable prognosis of myxoid liposarcoma, chemotherapy resistance remains a clinical problem. This cancer stem cell property is
Externí odkaz:
https://doaj.org/article/adf5270b00a744bfa928e2228023e756
Autor:
Amin Forootan, Daniel Andersson, Soheila Dolatabadi, David Svec, José Andrade, Anders Ståhlberg
Publikováno v:
Chemosensors, Vol 11, Iss 1, p 67 (2023)
Myxoid liposarcoma and Ewing sarcoma are the two most common tumor types that are characterized by the FET (FUS, EWSR1 and TAF15) fusion oncogenes. These FET fusion oncogenes are considered to have the same pathological mechanism. However, the cellul
Externí odkaz:
https://doaj.org/article/ceb8cde4a9354dc7bb17f9aa11872c98
Autor:
Christoffer Vannas, Lisa Andersson, Soheila Dolatabadi, Parmida Ranji, Malin Lindén, Emma Jonasson, Anders Ståhlberg, Henrik Fagman, Pierre Åman
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 624 (2022)
The therapeutic options for patients with relapsed or metastatic myxoid liposarcoma (MLS) remain scarce and there is currently no targeted therapy available. Inhibition of the HSP90 family of chaperones has been suggested as a possible therapeutic op
Externí odkaz:
https://doaj.org/article/95925dd05c4c4d0aa3024bc338a99d8e
Autor:
Emma Jonasson, Lisa Andersson, Soheila Dolatabadi, Salim Ghannoum, Pierre Åman, Anders Ståhlberg
Publikováno v:
Cells, Vol 9, Iss 3, p 759 (2020)
Single-cell analysis enables detailed molecular characterization of cells in relation to cell type, genotype, cell state, temporal variations, and microenvironment. These studies often include the analysis of individual genes and networks of genes. T
Externí odkaz:
https://doaj.org/article/2d5d4c9bc2414f5eb824d3147783cf58
Autor:
Anders Ståhlberg, Christina Kåbjörn Gustafsson, Katarina Engtröm, Christer Thomsen, Soheila Dolatabadi, Emma Jonasson, Chieh-Yuan Li, David Ruff, Shiaw-Min Chen, Pierre Åman
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113110 (2014)
Myxoid/round-cell liposarcoma (MLS/RCLS) is characterized by either the fusion gene FUS-DDIT3 or the less commonly occurring EWSR1-DDIT3 and most cases carry few or no additional cytogenetic changes. There are conflicting reports concerning the statu
Externí odkaz:
https://doaj.org/article/45e4cd054de640ec8dc801ef977d3215
Autor:
Soheila, Dolatabadi, Emma, Jonasson, Lisa, Andersson, Manuel, Luna Santamaría, Malin, Lindén, Tobias, Österlund, Pierre, Åman, Anders, Ståhlberg
Publikováno v:
Frontiers in oncology. 12
Myxoid liposarcoma is one of the most common sarcoma entities characterized by FET fusion oncogenes. Despite a generally favorable prognosis of myxoid liposarcoma, chemotherapy resistance remains a clinical problem. This cancer stem cell property is
Autor:
Christer Thomsen, Soheila Dolatabadi, Anders Ståhlberg, Pierre Åman, David Svec, Mark Shannon, Paul A. Fitzpatrick, Nicole Cordes, Göran Landberg
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
FUS-DDIT3 belongs to the FET (FUS, EWSR1, and TAF15) family of fusion oncogenes, which collectively are considered to be key players in tumor development. Even though over 90% of all myxoid liposarcomas (MLS) have a FUS-DDIT3 gene fusion, there is li
Publikováno v:
Scientific Reports
The need to perform gene expression profiling using next generation sequencing and quantitative real-time PCR (qPCR) on small sample sizes and single cells is rapidly expanding. However, to analyse few molecules, preamplification is required. Here, w
Autor:
Soheila, Dolatabadi, Julián, Candia, Nina, Akrap, Christoffer, Vannas, Tajana, Tesan Tomic, Wolfgang, Losert, Göran, Landberg, Pierre, Åman, Anders, Ståhlberg
Publikováno v:
Frontiers in Genetics
Cell proliferation includes a series of events that is tightly regulated by several checkpoints and layers of control mechanisms. Most studies have been performed on large cell populations, but detailed understanding of cell dynamics and heterogeneit