Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sohei Tsukita"'
Autor:
Kei-ichiro Inamori, Hideki Ito, Yumi Tamura, Takahiro Nitta, Xiaohua Yang, Wataru Nihei, Fumi Shishido, Susumu Imazu, Sohei Tsukita, Tetsuya Yamada, Hideki Katagiri, Jin-ichi Inokuchi
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1472-1481 (2018)
GM3, a precursor for synthesis of a- and b-series gangliosides, is elevated in adipocytes of obese model animals and in sera of obese human patients with type 2 diabetes and/or dyslipidemia. GM3 synthase (GM3S)-KO C57BL/6 mice display enhanced insuli
Externí odkaz:
https://doaj.org/article/1c54152b64d24af0a603f71aa4802730
Autor:
Toru Suzuki, Junhong Gao, Yasushi Ishigaki, Keiichi Kondo, Shojiro Sawada, Tomohito Izumi, Kenji Uno, Keizo Kaneko, Sohei Tsukita, Kei Takahashi, Atsuko Asao, Naoto Ishii, Junta Imai, Tetsuya Yamada, Seiichi Oyadomari, Hideki Katagiri
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 2045-2057 (2017)
Obesity represents chronic inflammatory states promoted by pro-inflammatory M1-macrophage infiltration into white adipose tissue (WAT), thereby inducing insulin resistance. Herein, we demonstrate the importance of an ER stress protein, CHOP, in deter
Externí odkaz:
https://doaj.org/article/bba53f47e339435f905712858ccfc4b1
Autor:
Sohei Tsukita, Tetsuya Yamada, Kei Takahashi, Yuichiro Munakata, Shinichiro Hosaka, Hironobu Takahashi, Junhong Gao, Yuta Shirai, Shinjiro Kodama, Yoichiro Asai, Takashi Sugisawa, Yumiko Chiba, Keizo Kaneko, Kenji Uno, Shojiro Sawada, Junta Imai, Hideki Katagiri
Publikováno v:
EBioMedicine, Vol 15, Iss C, Pp 163-172 (2017)
Major symptoms of diabetes mellitus manifest, once pancreatic β-cell numbers have become inadequate. Although natural regeneration of β-cells after injury is very limited, bone marrow (BM) transplantation (BMT) promotes their regeneration through u
Externí odkaz:
https://doaj.org/article/b378414ea3c8407c863d829ecbcd8641
Autor:
Yumiko Chiba, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, Yuichiro Munakata, Yuta Shirai, Shinjiro Kodama, Yoichiro Asai, Takashi Sugisawa, Kenji Uno, Shojiro Sawada, Junta Imai, Kazuhiro Nakamura, Hideki Katagiri
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150756 (2016)
Selective sodium glucose cotransporter-2 inhibitor (SGLT2i) treatment promotes urinary glucose excretion, thereby reducing blood glucose as well as body weight. However, only limited body weight reductions are achieved with SGLT2i treatment. Hyperpha
Externí odkaz:
https://doaj.org/article/757ebc58e8014a75a2c8d226d47bad33
Autor:
Kazuki Noda, Sota Nakajima, Shigeo Godo, Hiroki Saito, Shohei Ikeda, Toru Shimizu, Budbazar Enkhjargal, Yoshihiro Fukumoto, Sohei Tsukita, Tetsuya Yamada, Hideki Katagiri, Hiroaki Shimokawa
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e110446 (2014)
BACKGROUND: Metabolic disorders, caused by excessive calorie intake and low physical activity, are important cardiovascular risk factors. Rho-kinase, an effector protein of the small GTP-binding protein RhoA, is an important cardiovascular therapeuti
Externí odkaz:
https://doaj.org/article/951c08e00d974e4eb70c68c30b1661fd
Autor:
Shinjiro Kodama, Tetsuya Yamada, Junta Imai, Shojiro Sawada, Kei Takahashi, Sohei Tsukita, Keizo Kaneko, Kenji Uno, Yasushi Ishigaki, Yoshitomo Oka, Hideki Katagiri
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e88602 (2014)
Genetic factors play very important roles in the onset and progression of type 2 diabetes mellitus (T2DM). However, the genetic factors correlating with T2DM onset have not as yet been fully clarified. We previously found that copy number losses in t
Externí odkaz:
https://doaj.org/article/805aba361d304c4bb96a590a26444e14
Autor:
Wataru Nihei, Yumi Tamura, Kei-ichiro Inamori, Susumu Imazu, Hideki Ito, Hideki Katagiri, Xiaohua Yang, Sohei Tsukita, Jin-ichi Inokuchi, Takahiro Nitta, Fumi Shishido, Tetsuya Yamada
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1472-1481 (2018)
GM3, a precursor for synthesis of a- and b-series gangliosides, is elevated in adipocytes of obese model animals and in sera of obese human patients with type 2 diabetes and/or dyslipidemia. GM3 synthase (GM3S)-KO C57BL/6 mice display enhanced insuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c784f2312833424863c3565a463046e
https://doi.org/10.1194/jlr.m085753
https://doi.org/10.1194/jlr.m085753
Autor:
Kei Takahashi, Yumiko Chiba, Shinjiro Kodama, Shojiro Sawada, Sohei Tsukita, Yoichiro Asai, Keizo Kaneko, Junta Imai, Hironobu Takahashi, Shinichiro Hosaka, Takashi Sugisawa, Yuta Shirai, Junhong Gao, Tetsuya Yamada, Kenji Uno, Hideki Katagiri, Yuichiro Munakata
Publikováno v:
EBioMedicine
EBioMedicine, Vol 15, Iss C, Pp 163-172 (2017)
EBioMedicine, Vol 15, Iss C, Pp 163-172 (2017)
Major symptoms of diabetes mellitus manifest, once pancreatic β-cell numbers have become inadequate. Although natural regeneration of β-cells after injury is very limited, bone marrow (BM) transplantation (BMT) promotes their regeneration through u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc770c0df5bdf311c5504f86f5224957
Autor:
Shojiro Sawada, Kei Takahashi, Atsuko Asao, Keiichi Kondo, Seiichi Oyadomari, Naoto Ishii, Keizo Kaneko, Toru Suzuki, Sohei Tsukita, Tomohito Izumi, Tetsuya Yamada, Yasushi Ishigaki, Kenji Uno, Hideki Katagiri, Junhong Gao, Junta Imai
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 2045-2057 (2017)
Obesity represents chronic inflammatory states promoted by pro-inflammatory M1-macrophage infiltration into white adipose tissue (WAT), thereby inducing insulin resistance. Herein, we demonstrate the importance of an ER stress protein, CHOP, in deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8606f07ff718e8e78e84837673d14db6
Autor:
Takashi Sugisawa, Toru Suzuki, Yasushi Ishigaki, Shojiro Sawada, Takeyoshi Murano, Tetsuya Yamada, Sohei Tsukita, Takashi Yamaguchi, Shinjiro Kodama, Hideki Katagiri, Junta Imai
Publikováno v:
Internal Medicine. 55:1131-1136
Lipoprotein lipase (LPL) deficiency is a rare monogenic disorder that manifests as severe hypertriglyceridemia. Whether or not LPL deficiency accelerates the development of atherosclerosis remains controversial. We herein report a 66-year-old woman w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4123e3e8d00e5397f158de1e04a2669
https://doi.org/10.2169/internalmedicine.55.5239
https://doi.org/10.2169/internalmedicine.55.5239