Výsledky vyhledávání - "Sohail Malik"

Akademický článek

Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer.

Autor: Yan Zhang, Andrei Pavlov, Sohail Malik, Hong Chen, Nancy Kim, Ziqing Li, Xiaohong Zhang, Melvin L DePamphilis, Robert G Roeder, Hui Ge

Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0230670 (2020)

The human positive coactivator 4 (PC4) was originally identified as a multi-functional cofactor capable of mediating transcription activation by diverse gene- and tissue-specific activators. Recent studies suggest that PC4 might also function as a no

Externí odkaz: https://doaj.org/article/b0f49e0a8dc4422884a65b333e484cae

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Akademický článek

Thermoelastic Investigation of Carbon-Fiber-Reinforced Composites Using a Drop-Weight Impact Test

Autor: Zahra Andleeb, Sohail Malik, Hassan Abbas Khawaja, Anders Samuelsen Nordli, Ståle Antonsen, Ghulam Hussain, Mojtaba Moatamedi

Publikováno v: Applied Sciences, Vol 11, Iss 1, p 207 (2020)

Composite materials are becoming more popular in technological applications due to the significant weight savings and strength offered by these materials compared to metallic materials. In many of these practical situations, the structures suffer fro

Externí odkaz: https://doaj.org/article/77c2b8535721472ca4f8b5bfa7b5303e

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Akademický článek

TFIIB is only ∼9 Å away from the 5'-end of a trimeric RNA primer in a functional RNA polymerase II preinitiation complex.

Autor: Matthew J Bick, Sohail Malik, Arkady Mustaev, Seth A Darst

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119007 (2015)

Recent X-ray crystallographic studies of Pol II in complex with the general transcription factor (GTF) IIB have begun to provide insights into the mechanism of transcription initiation. These structures have also shed light on the architecture of the

Externí odkaz: https://doaj.org/article/85b62fd352da4ed4a6a874f270a20e7f

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