Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sohail F, Tavazoie"'
Autor:
Lisa B. Earnest-Noble, Dennis Hsu, Siyu Chen, Hosseinali Asgharian, Mandayam Nandan, Maria C. Passarelli, Hani Goodarzi, Sohail F. Tavazoie
Publikováno v:
Nature Cancer. 3:1484-1497
The human genome contains 61 codons encoding 20 amino acids. Synonymous codons representing a given amino acid are decoded by a set of transfer RNAs (tRNAs) called isoacceptors. We report the surprising observation that two isoacceptor tRNAs that dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180b622ed9ef809da49320925f06e478
https://doi.org/10.1038/s43018-022-00469-9
https://doi.org/10.1038/s43018-022-00469-9
Autor:
Norihiro Yamaguchi, Ethan M Weinberg, Alexander Nguyen, Maria V Liberti, Hani Goodarzi, Yelena Y Janjigian, Philip B Paty, Leonard B Saltz, T Peter Kingham, Jia Min Loo, Elisa de Stanchina, Sohail F Tavazoie
Publikováno v:
eLife, Vol 8 (2019)
Colorectal cancer (CRC) is a major cause of human death. Mortality is primarily due to metastatic organ colonization, with the liver being the main organ affected. We modeled metastatic CRC (mCRC) liver colonization using patient-derived primary and
Externí odkaz:
https://doaj.org/article/df6349d3163c42688775653c831ce857
Autor:
Benjamin N. Ostendorf, Mira A. Patel, Jana Bilanovic, H.-Heinrich Hoffmann, Sebastian E. Carrasco, Charles M. Rice, Sohail F. Tavazoie
Publikováno v:
Nature. 611:346-351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c33cc6191ea50aa676495b55029fd0
https://doi.org/10.1038/s41586-022-05344-2
https://doi.org/10.1038/s41586-022-05344-2
Supplementary Figure S1 contains TMEM2 protein expression levels in human cancer. Supplementary Figure S2 contains quantification of mRNA levels of TMEM2 in the context of SOX4 knockdown or overexpression. Supplementary Figure S3 contains western blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14493a6094b0a6eeb4072ffd02f6b339
https://doi.org/10.1158/0008-5472.22408763.v1
https://doi.org/10.1158/0008-5472.22408763.v1
This file contains supplementary figure legends only.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f5485cf57c6f9905ea26968ea506bc
https://doi.org/10.1158/0008-5472.22408766.v1
https://doi.org/10.1158/0008-5472.22408766.v1
The developmental transcription factor SOX4 contributes to the metastatic spread of multiple solid cancer types, but its direct target genes that mediate cancer progression are not well defined. Using a systematic molecular and genomic approach, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d61d9acc9ef9bfb759239e12b410551
https://doi.org/10.1158/0008-5472.c.6507611.v1
https://doi.org/10.1158/0008-5472.c.6507611.v1
Autor:
Maria C. Passarelli, Alexandra M. Pinzaru, Hosseinali Asgharian, Maria V. Liberti, Søren Heissel, Henrik Molina, Hani Goodarzi, Sohail F. Tavazoie
Publikováno v:
Nature cell biology, vol 24, iss 3
Tumourigenesis and cancer progression require enhanced global protein translation1-3. Such enhanced translation is caused by oncogenic and tumour-suppressive events that drive the synthesis and activity of translational machinery4,5. Here we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c12d705ba661874dbbd565e0d7eb20e
https://doi.org/10.1038/s41556-022-00856-5
https://doi.org/10.1038/s41556-022-00856-5
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Phenotypic and genetic intra-tumor heterogeneity have an important role in cancer progression and therapeutic resistance. Here, the authors show that phenotypically variable tumor subpopulations exhibit higher metastatic potential and display enhance
Externí odkaz:
https://doaj.org/article/7e299b798cc044399ba376b2b8746bde
Autor:
Dennis J. Hsu, Jenny Gao, Norihiro Yamaguchi, Alexandra Pinzaru, Qiushuang Wu, Nandan Mandayam, Maria Liberti, Søren Heissel, Hanan Alwaseem, Saeed Tavazoie, Sohail F. Tavazoie
Publikováno v:
Science advances. 9(1)
Utilization of specific codons varies between organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e4282ec7dc50cf55a05c3194a0b438
https://pubmed.ncbi.nlm.nih.gov/36608131
https://pubmed.ncbi.nlm.nih.gov/36608131
Autor:
Dennis J. Hsu, Jenny Gao, Norihiro Yamaguchi, Alexandra Pinzaru, Nandan Mandayam, Maria Liberti, Søren Heissel, Hanan Alwaseem, Saeed Tavazoie, Sohail F. Tavazoie
Utilization of specific codons varies significantly across organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f2a6d490e25184f298f8dd662847ef
https://doi.org/10.1101/2023.01.02.521806
https://doi.org/10.1101/2023.01.02.521806