Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Soha Parsafar"'
Autor:
Zahra Nayeri, Farhang Aliakbari, Farzaneh Afzali, Soha Parsafar, Ehsan Gharib, Daniel E. Otzen, Dina Morshedi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Despite extensive research, the molecular mechanisms underlying the toxicity of αSN in Parkinson’s disease (PD) pathology are still poorly understood. To address this, we used a microarray dataset to identify genes that are induced and differentia
Externí odkaz:
https://doaj.org/article/7f52cb14bb564d0e85ae8119564a3f87
Autor:
Soha Parsafar, Zahra Nayeri, Farhang Aliakbari, Farshad Shahi, Mehdi Mohammadi, Dina Morshedi
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04737- (2020)
Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders with no precise etiology. Multiple lines of evidence support that environmental factors, either neurotoxins or neuroinflammation, can induce Parkinsonism. In this study
Externí odkaz:
https://doaj.org/article/7a1dfc1bffad4752bfc8f3039210ba82
Publikováno v:
مجله دانشکده پزشکی اصفهان, Vol 33, Iss 330, Pp 484-494 (2015)
Background: The PIK3CA oncogene, which encodes p110α, is one of the most mutated genes in human cancers such as colorectal. A polymorphic GT dinucleotide repeat exists in intron 1 of the PIK3CA gene. Till this research, there were no study on polymo
Externí odkaz:
https://doaj.org/article/9d55cc55d5444b0ebd22e30ec96f2db2
Autor:
Soha Parsafar, Farhang Aliakbari, Sepideh Sadat Seyedfatemi, Zahra Najarzadeh, Hamdam Hourfar, Hassan Bardania, Mohsen Farhadpour, Mehdi Mohammadi, Dina Morshedi
Publikováno v:
Parsafar, S, Aliakbari, F, Seyedfatemi, S S, Najarzadeh, Z, Hourfar, H, Bardania, H, Farhadpour, M, Mohammadi, M & Morshedi, D 2022, ' Insights into the inhibitory mechanism of skullcapflavone II against α-synuclein aggregation and its mediated cytotoxicity ', International Journal of Biological Macromolecules, vol. 209, no. Part A, pp. 426-440 . https://doi.org/10.1016/j.ijbiomac.2022.03.092
The dangerous self-assembled and infectious seeds of α-synuclein (αSN) play primary roles in Parkinson's disease. Accordingly, the inhibition of αSN fibrillation and elimination of toxic aggregates are the main therapeutic strategies. Skullcapflav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7080be38f4ddfb0e1588faeaee82a42f
https://doi.org/10.1016/j.ijbiomac.2022.03.092
https://doi.org/10.1016/j.ijbiomac.2022.03.092
Autor:
Gunna Christiansen, Shahsanam Abbasi, Dina Morshedi, Azita Parvaneh Tafreshi, Farhang Aliakbari, Nasrollah Rezaei-Ghaleh, Poul Henning Jensen, Peter B. O’Connor, Stefan Becker, Duncan S. Sutherland, Frederik Lermyte, Hossein Mohammad-Beigi, Daniel E. Otzen, Joanna F. Collingwood, Soha Parsafar
Publikováno v:
Aliakbari, F, Mohammad-Beigi, H, Abbasi, S, Rezaei-Ghaleh, N, Lermyte, F, Parsafar, S, Becker, S, Tafreshi, A P, O'Connor, P B, Collingwood, J F, Christiansen, G, Sutherland, D S, Jensen, P H, Morshedi, D & Otzen, D E 2021, ' Multiple Protective Roles of Nanoliposome-Incorporated Baicalein against Alpha-Synuclein Aggregates ', Advanced Functional Materials, vol. 31, no. 7, 2007765 . https://doi.org/10.1002/adfm.202007765
Nanoparticles are useful for increasing drug stability, solubility, and availability. The small molecule baicalein inhibits fibrillation, and detoxifies aggregates of α-synuclein (αSN) associated with Parkinson's disease (PD), but it suffers from i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221a4c8ca0017f6a9cf37e46a2df9662
https://pure.au.dk/portal/da/publications/multiple-protective-roles-of-nanoliposomeincorporated-baicalein-against-alphasynuclein-aggregates(a760e08c-d07b-4156-91f7-2c37f317eea7).html
https://pure.au.dk/portal/da/publications/multiple-protective-roles-of-nanoliposomeincorporated-baicalein-against-alphasynuclein-aggregates(a760e08c-d07b-4156-91f7-2c37f317eea7).html
Autor:
Farshad Shahi, Dina Morshedi, Soha Parsafar, Farhang Aliakbari, Mehdi Mohammadi, Zahra Nayeri
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04737-(2020)
Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders with no precise etiology. Multiple lines of evidence support that environmental factors, either neurotoxins or neuroinflammation, can induce Parkinsonism. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a76500bd2996f6716542a15c93fc788
https://doi.org/10.1016/j.heliyon.2020.e04737
https://doi.org/10.1016/j.heliyon.2020.e04737
Autor:
Seyed-Morteza Javadirad, Mansoureh Azadeh, Leila Assad Samani, Soha Parsafar, Hossein Tabatabaeian, Kamran Ghaedi
Publikováno v:
Indian J Clin Biochem
Breast cancer as the second most common cancer worldwide tend to be experienced by Iranian women 10 years earlier with a peak incidence at the premenopausal stage. Genetic mutations of TP53 tumor suppressor gene has been shown to be related to early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b889842c78a144cc360ab86ba0844b
https://europepmc.org/articles/PMC6801240/
https://europepmc.org/articles/PMC6801240/
Autor:
Masoumeh Mansouri Bidkani, Mohammad Fazilati, Kamran Ghaedi, Soha Parsafar, Nafezeh Ghanei, Hossein Tabatabaeian
Publikováno v:
Breast (Edinburgh, Scotland). 42
Purpose A number of single nucleotide polymorphisms (SNPs) in EebB4 gene have been studied, which has clarified their impact on breast cancer in different populations. Nevertheless, the importance of rs13423759 in breast cancer has not been studied a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56638ecb9eb521fe8bdab48cff10d55
https://pubmed.ncbi.nlm.nih.gov/30336339
https://pubmed.ncbi.nlm.nih.gov/30336339
Publikováno v:
Cancer biomarkers : section A of Disease markers. 15(4)
BACKGROUND Activated PI3K generate PIP3 to trigger different signaling pathways which regulate a number of cellular functions including cell survival, apoptosis, proliferation and motility. Mutations in many cancers were discovered in the gene encodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea77878f4ec5821ddc62433dad3d84e
https://pubmed.ncbi.nlm.nih.gov/25835181
https://pubmed.ncbi.nlm.nih.gov/25835181