Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sofya A. Polyanskaya"'
Autor:
Christopher R. Vakoc, Agata Smogorzewska, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Osama E. Demerdash, Melissa Kramer, Joseph P. Milazzo, Olaf Klingbeil, Emmalee R. Adelman, Francis P. Lach, Moonjung Jung, Shruti V. Iyer, Sofya A. Polyanskaya, Yiliang Wei, Xiaoli S. Wu, Zhaolin Yang
CRISPR screening data using the E2/E3 sgRNA library in 12 cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc896b5f476790258396e2a9e0e80c1
https://doi.org/10.1158/2159-8290.22540088
https://doi.org/10.1158/2159-8290.22540088
Autor:
Christopher R. Vakoc, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Sofya A. Polyanskaya, Osama E. Demerdash, Olaf Klingbeil, Emmalee R. Adelman, Melissa Kramer, Zhaolin Yang, Ana S.H. Costa, Shruti V. Iyer, Damianos S. Skopelitis, Yu-Han Huang, Yiliang Wei
Supplementary Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cf70d903de0c807ee13b3006ac8c34
https://doi.org/10.1158/2159-8290.22540466
https://doi.org/10.1158/2159-8290.22540466
Supplementary Figures S1-S17 from SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia
Autor:
Christopher R. Vakoc, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Sofya A. Polyanskaya, Osama E. Demerdash, Olaf Klingbeil, Emmalee R. Adelman, Melissa Kramer, Zhaolin Yang, Ana S.H. Costa, Shruti V. Iyer, Damianos S. Skopelitis, Yu-Han Huang, Yiliang Wei
Figures S1 to S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e662c53944ae25bb50182b91581bd81c
https://doi.org/10.1158/2159-8290.22540472
https://doi.org/10.1158/2159-8290.22540472
Autor:
Christopher R. Vakoc, Agata Smogorzewska, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Osama E. Demerdash, Melissa Kramer, Joseph P. Milazzo, Olaf Klingbeil, Emmalee R. Adelman, Francis P. Lach, Moonjung Jung, Shruti V. Iyer, Sofya A. Polyanskaya, Yiliang Wei, Xiaoli S. Wu, Zhaolin Yang
Hundreds of genes become aberrantly silenced in acute myeloid leukemia (AML), with most of these epigenetic changes being of unknown functional consequence. Here, we demonstrate how gene silencing can lead to an acquired dependency on the DNA repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af2b7c42f06fde3a5b35a86833cbf58
https://doi.org/10.1158/2159-8290.c.6549278.v1
https://doi.org/10.1158/2159-8290.c.6549278.v1
Autor:
Christopher R. Vakoc, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Sofya A. Polyanskaya, Osama E. Demerdash, Olaf Klingbeil, Emmalee R. Adelman, Melissa Kramer, Zhaolin Yang, Ana S.H. Costa, Shruti V. Iyer, Damianos S. Skopelitis, Yu-Han Huang, Yiliang Wei
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c16067cf54850ca35e975820451a4f
https://doi.org/10.1158/2159-8290.22540469
https://doi.org/10.1158/2159-8290.22540469
Autor:
Christopher R. Vakoc, Agata Smogorzewska, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Osama E. Demerdash, Melissa Kramer, Joseph P. Milazzo, Olaf Klingbeil, Emmalee R. Adelman, Francis P. Lach, Moonjung Jung, Shruti V. Iyer, Sofya A. Polyanskaya, Yiliang Wei, Xiaoli S. Wu, Zhaolin Yang
The E2/E3 sgRNA guide sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e531a1a5aa2df3cb808f2992ff63ff
https://doi.org/10.1158/2159-8290.22540091.v1
https://doi.org/10.1158/2159-8290.22540091.v1
Autor:
Christopher R. Vakoc, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Sofya A. Polyanskaya, Osama E. Demerdash, Olaf Klingbeil, Emmalee R. Adelman, Melissa Kramer, Zhaolin Yang, Ana S.H. Costa, Shruti V. Iyer, Damianos S. Skopelitis, Yu-Han Huang, Yiliang Wei
An enhanced requirement for nutrients is a hallmark property of cancer cells. Here, we optimized an in vivo genetic screening strategy in acute myeloid leukemia (AML), which led to the identification of the myo-inositol transporter SLC5A3 as a depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c303aa3d7206f473a52cac69e4886b59
https://doi.org/10.1158/2159-8290.c.6549386.v1
https://doi.org/10.1158/2159-8290.c.6549386.v1
Autor:
Christopher R. Vakoc, Agata Smogorzewska, Maria E. Figueroa, W. Richard McCombie, Emily Hodges, Sara Goodwin, Kenneth Chang, Osama E. Demerdash, Melissa Kramer, Joseph P. Milazzo, Olaf Klingbeil, Emmalee R. Adelman, Francis P. Lach, Moonjung Jung, Shruti V. Iyer, Sofya A. Polyanskaya, Yiliang Wei, Xiaoli S. Wu, Zhaolin Yang
Sequences of additional sgRNA and primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06beb9eb8bf11c8ec6c98ea8e4d08ea7
https://doi.org/10.1158/2159-8290.22540085
https://doi.org/10.1158/2159-8290.22540085
Autor:
Yiliang Wei, W. Richard McCombie, Yu-Han Huang, Damianos S. Skopelitis, Emily Hodges, Ana S. H. Costa, Zhaolin Yang, Maria E. Figueroa, Christopher R. Vakoc, Emmalee R. Adelman, Osama El Demerdash, Sofya A. Polyanskaya, Olaf Klingbeil, Kenneth Chang, Sara Goodwin, Melissa Kramer, Shruti V. Iyer
Publikováno v:
Cancer Discov
An enhanced requirement for nutrients is a hallmark property of cancer cells. Here, we optimized an in vivo genetic screening strategy in acute myeloid leukemia (AML), which led to the identification of the myo-inositol transporter SLC5A3 as a depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6118793b9953608b6a6cea923272603
https://doi.org/10.1158/2159-8290.cd-20-1849
https://doi.org/10.1158/2159-8290.cd-20-1849
Autor:
Agata Smogorzewska, Christopher R. Vakoc, Sofya A. Polyanskaya, Olaf Klingbeil, Zhaolin Yang, Sara Goodwin, Francis P. Lach, Emily Hodges, Kenneth Chang, Joseph P. Milazzo, Melissa Kramer, Osama El Demerdash, Yiliang Wei, Emmalee R. Adelman, Moonjung Jung, Maria E. Figueroa, Xiaoli S. Wu, W. Richard McCombie, Shruti V. Iyer
Publikováno v:
Cancer Discov
Hundreds of genes become aberrantly silenced in acute myeloid leukemia (AML), with most of these epigenetic changes being of unknown functional consequence. Here, we demonstrate how gene silencing can lead to an acquired dependency on the DNA repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded1f67aa15f1c3b8d3211e27409c49d
https://doi.org/10.1158/2159-8290.cd-20-1542
https://doi.org/10.1158/2159-8290.cd-20-1542