Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sofya A. Kasatskaya"'
Autor:
Pavel V. Shelyakin, Ksenia R. Lupyr, Evgeny S. Egorov, Ilya A. Kofiadi, Dmitriy B. Staroverov, Sofya A. Kasatskaya, Valeriia V. Kriukova, Irina A. Shagina, Ekaterina M. Merzlyak, Tatiana O. Nakonechnaya, Elena A. Latysheva, Irina A. Manto, Musa R. Khaitov, Sergey A. Lukyanov, Dmitriy M. Chudakov, Olga V. Britanova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The interplay between T- and B-cell compartments during naïve, effector and memory T cell maturation is critical for a balanced immune response. Primary B-cell immunodeficiency arising from X-linked agammaglobulinemia (XLA) offers a model to explore
Externí odkaz:
https://doaj.org/article/9b8c5dfdc92d41599dda081cf8de303f
Autor:
Martin S. Davey, Carrie R. Willcox, Stuart Hunter, Sofya A. Kasatskaya, Ester B. M. Remmerswaal, Mahboob Salim, Fiyaz Mohammed, Frederike J. Bemelman, Dmitriy M. Chudakov, Ye H. Oo, Benjamin E. Willcox
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Human Vδ2+ γδ T cells are thought to be an innate-like T-cell population. Here the authors show the Vδ2+ compartment contains both innate-like Vγ9+ and an adaptive Vγ9- subset that undergoes clonal expansion during viral infection and can infil
Externí odkaz:
https://doaj.org/article/34013345c36840c6887dde5ba30f872e
Autor:
Martin S. Davey, Carrie R. Willcox, Stephen P. Joyce, Kristin Ladell, Sofya A. Kasatskaya, James E. McLaren, Stuart Hunter, Mahboob Salim, Fiyaz Mohammed, David A. Price, Dmitriy M. Chudakov, Benjamin E. Willcox
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has ad
Externí odkaz:
https://doaj.org/article/e1ccfb7e084e42f698fa39ef31fcea3d
Autor:
Evgeny S. Egorov, Sofya A. Kasatskaya, Vasiliy N. Zubov, Mark Izraelson, Tatiana O. Nakonechnaya, Dmitriy B. Staroverov, Andrea Angius, Francesco Cucca, Ilgar Z. Mamedov, Elisa Rosati, Andre Franke, Mikhail Shugay, Mikhail V. Pogorelyy, Dmitriy M. Chudakov, Olga V. Britanova
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Human aging is associated with a profound loss of thymus productivity, yet naïve T lymphocytes still maintain their numbers by division in the periphery for many years. The extent of such proliferation may depend on the cytokine environment, includi
Externí odkaz:
https://doaj.org/article/3353536f827240dd8de351aabf48629c
Autor:
Dmitry B. Staroverov, Dmitriy M. Chudakov, Kelly L. Miners, Alexey N. Davydov, Sofya A. Kasatskaya, Irina A. Shagina, Ilgar Z. Mamedov, Kristin Ladell, Pavel V. Shelyakin, Elena K Matveyshina, Olga V. Britanova, Maria Metsger, Mark Izraelson, David Price, Evgeniy S. Egorov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4614aaf320bd98943599772077f765
https://doi.org/10.7554/elife.57063.sa2
https://doi.org/10.7554/elife.57063.sa2
Autor:
Sofya A, Kasatskaya, Kristin, Ladell, Evgeniy S, Egorov, Kelly L, Miners, Alexey N, Davydov, Maria, Metsger, Dmitry B, Staroverov, Elena K, Matveyshina, Irina A, Shagina, Ilgar Z, Mamedov, Mark, Izraelson, Pavel V, Shelyakin, Olga V, Britanova, David A, Price, Dmitriy M, Chudakov
Publikováno v:
eLife
The organizational integrity of the adaptive immune system is determined by functionally discrete subsets of CD4+ T cells, but it has remained unclear to what extent lineage choice is influenced by clonotypically expressed T-cell receptors (TCRs). To
Autor:
Bruno Moltedo, Olga V. Britanova, Tatiana O Nakonechnaya, Irina I. Shemiakina, Dmitriy A. Bolotin, Mark Izraelson, Alexander Y. Rudensky, Ekaterina V. Putintseva, Evgeniy S. Egorov, Sofya A. Kasatskaya, Dmitriy M. Chudakov, Dmitriy B. Staroverov, Maria Y. Zakharova, Ilgar Z. Mamedov, Mikhail Shugay, Alexey N. Davydov
Publikováno v:
Immunology. 153:133-144
For understanding the rules and laws of adaptive immunity, high‐throughput profiling of T‐cell receptor (TCR) repertoires becomes a powerful tool. The structure of TCR repertoires is instructive even before the antigen specificity of each particu
Autor:
M. A. Israelson, Olga V. Britanova, P. I. Novikov, Sofya A. Kasatskaya, Dmitry B. Staroverov, Ekaterina M. Merzlyak, Dmitry M. Chudakov, Tatiana O Nakonechnaya, A. V. Sosnovskaya
Publikováno v:
Bulletin of Russian State Medical University. :68-74
Autor:
Thomas Höllt, Olga V. Britanova, Tamim Abdelaal, Mark Izraelson, Nannan Guo, Sofya A. Kasatskaya, Na Li, Boudewijn P. F. Lelieveldt, Jeroen Eggermont, David Price, Dmitriy M. Chudakov, Frits Koning, Susana M. Chuva de Sousa Lopes, Evgeny S. Egorov, Noel F C C de Miranda, Vincent van Unen, James E. McLaren, Kristin Ladell
Publikováno v:
Nature Immunology, 20(3), 301
Nature Immunology
Nature immunology
Nature Immunology
Nature immunology
The fetus is thought to be protected from exposure to foreign antigens, yet CD45RO+ T cells reside in the fetal intestine. Here we combined functional assays with mass cytometry, single-cell RNA-sequencing and high-throughput T cell antigen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef456433c6d83571a16393c988faa39
Autor:
Michael Maschan, A. A. Maschan, Sofya A. Kasatskaya, Ivan V. Zvyagin, Mikhail Shugay, Ekaterina A. Komech, D.N. Balashov, O V Tatarinova, Anastasiia L. Sycheva, V.V. Brilliantova, E V Boyakova, Larisa Shelikhova, Y B Lebedev, Elena Kurnikova, Dmitry M. Chudakov, Ilgar Z. Mamedov
Publikováno v:
Leukemia. 31:1145-1153
αβT-cell-depleted allogeneic hematopoietic cell transplantation holds promise for the safe and accessible therapy of both malignant and non-malignant blood disorders. Here we employed molecular barcoding normalized T-cell receptor (TCR) profiling t