Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sofotasiou M"'
Non-alcoholic fatty liver disease (NAFLD) is among the most common liver pathologies, however, none approved condition-specific therapy yet exists. The present study introduces a drug repositioning (DR) approach that combines in vitro steatosis model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::e728658441ccc737d66e15c81f568be7
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056185
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056185
Poly (ADP-ribose) polymerase 1 (PARP-1) has a central role in the repair of DNA breaks and is a promising treatment target in malignancy. We measured PARP1 mRNA levels by a SYBR-green-based PCR in the bone marrow of 74 patients with myelodysplastic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::84063144bf703787f574db1954d9ebce
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3109058
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3109058
Background: The tumor protein p53 (TP53) gene may be inactivated through 17p13 deletion, somatic mutations, or both. In chronic lymphocytic leukemia (CLL) although 17p13 deletion is correlated with poor prognosis, the role of sole TP53 mutations rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::c7789e1cfb2980453e9a7703b7a8c4bb
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087085
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087085
Signal transducer and activator of transcription (STAT) proteins have been intensively studied in hematologic malignancies, and the efficacy of agents against STATs in lymphomas is already under research. We investigated the expression of total STAT5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::1b97dc15a0197adceaeccd129051f678
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087022
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087022
Akademický článek
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Background Epstein-Barr virus (EBV) is a ubiquitous pathogen that chronically infects B lymphocytes and is implicated in the pathogenesis of lymphoproliferative diseases. Latent membrane protein 1 (LMP1), the major oncoprotein of the virus, has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::61975e0dfe9c595e0ad83d669fc1e3e0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088869
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088869
Chronic lymphocytic leukemia (CLL) is considered a malignancy resulting from defects in apoptosis. For this reason, targeting apoptotic pathways in CLL may be valuable for its management. Poly [ADP-ribose] polymerase 1 (PARP1) is the main member of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::8dfd083287b0d1cfd4b2eeb1adeeb53c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3001765
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3001765
Fc-γ RIIA (CD32), a member of the family of Fc-γ receptors, participates in the phagocytosis of bound to antibody antigens. The effectiveness of this function varies for its several haplotypes, and it participates in the pathogenesis of viral infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::4620ceba20853a926771d8426b804742
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088330
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088330
Akademický článek
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