Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sofiya A Galkina"'
Autor:
Cheryl A Stoddart, Cheryl A Bales, Jennifer C Bare, George Chkhenkeli, Sofiya A Galkina, April N Kinkade, Mary E Moreno, José M Rivera, Rollie E Ronquillo, Barbara Sloan, Paul L Black
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e655 (2007)
The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals.E
Externí odkaz:
https://doaj.org/article/fb047b72aca54c4094161004657b21ea
Autor:
Cheryl A. Stoddart, Galina Kosikova, Michal Caspi Tal, Jose M. Rivera, Karl S. Lang, Anfei Huang, Sofiya A. Galkina, Hilal Bhat, Laughing Bear Torrez Dulgeroff, Mary E. Moreno, Fanghui Li, Lara Myers, Tom Adomati, Kim J. Hasenkrug, Irving L. Weissman, Joseph M. McCune, Philipp A. Lang, Lamin B. Cham
Publikováno v:
Cell reports
Cell reports, vol 31, iss 2
Cell reports, vol 31, iss 2
SUMMARY Paradoxically, early host responses to infection include the upregulation of the antiphagocytic molecule, CD47. This suggests that CD47 blockade could enhance antigen presentation and subsequent immune responses. Indeed, mice treated with ant
Autor:
Mary E. Moreno, Pheroze Joshi, Sofiya A. Galkina, Ma Somsouk, Ekaterina Maidji, Jose M. Rivera, Cheryl A. Stoddart, Galina Kosikova
Publikováno v:
Viruses, vol 11, iss 3
Viruses
Volume 11
Issue 3
Viruses, Vol 11, Iss 3, p 256 (2019)
Viruses
Volume 11
Issue 3
Viruses, Vol 11, Iss 3, p 256 (2019)
Although antiretroviral therapy (ART) greatly suppresses HIV replication, lymphoid tissues remain a sanctuary site where the virus may replicate. Tracking the earliest steps of HIV spread from these cellular reservoirs after drug cessation is pivotal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa41d920c47e050dcb14bb6eccace994
https://escholarship.org/uc/item/0bp322bk
https://escholarship.org/uc/item/0bp322bk
Autor:
Mary E. Moreno, Michael Murphey-Corb, Stefan G. Sarafianos, Jose M. Rivera, Barbara Sloan, Cheryl A. Stoddart, Galina Kosikova, Pheroze Joshi, Michael A. Parniak, Sofiya A. Galkina, Aaron B. Reeve
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 7
Like normal cellular nucleosides, the nucleoside reverse transcriptase (RT) inhibitor (NRTI) 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) has a 3′-hydroxyl moiety, and yet EFdA is a highly potent inhibitor of human immunodeficiency virus (HIV)
Autor:
Witold Cieplak, Brian Long, Terri Wrin, Barbara Sloan, Jose M. Rivera, Sofiya A. Galkina, Ukina R. Sanford, Mary E. Moreno, Po-Ying Chan-Hui, Pheroze Joshi, Ekaterina Maidji, Cheryl A. Stoddart, Galina Kosikova
Publikováno v:
Virology, vol 462-463, iss 1
Highly potent broadly neutralizing human monoclonal antibodies hold promise for HIV prophylaxis and treatment. We used the SCID-hu Thy/Liv and BLT humanized mouse models to study the efficacy of these antibodies, primarily PG16, against HIV-1 clades
Autor:
Geneviève Nault, Sofiya A. Galkina, Omar Quraishi, Nathalie Bousquet-Gagnon, Dominique P. Bridon, Cheryl A. Stoddart
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:2162-2165
PC-1505 is a C34 peptide derived from the heptad repeat 2 region of HIV-1 gp41 conjugated to human serum albumin for sustained in vivo activity. One single preexposure dose of PC-1505 reduced viral RNA in HIV-1-infected SCID-hu Thy/Liv mice by 3.3 lo
Autor:
Pheroze Joshi, Sofiya A. Galkina, Ekaterina Maidji, Cheryl A. Stoddart, Galina Kosikova, Barbara Sloan, Mary E. Moreno, Brian Long, Jose M. Rivera
Publikováno v:
Virology. 417(1):154-160
Humanized Bone marrow/Liver/Thymus (BLT) mice recapitulate the mucosal transmission of HIV, permitting study of early events in HIV pathogenesis and evaluation of preexposure prophylaxis methods to inhibit HIV transmission. Human hematopoiesis is rec
Autor:
Nathalie Bousquet-Gagnon, Maryanne Bellomo, Marie K. Mankowski, Cheryl A. Stoddart, Véronique Paradis, Karen Thibaudeau, Geneviève Nault, Martin Robitaille, Sofiya A. Galkina, Patricia Liscourt, Dominique P. Bridon, Roger G. Ptak, Omar Quraishi, Marie-Ève Rivard, Peter Bakis, Alexandra Lobach
Publikováno v:
The Journal of Biological Chemistry
Entry inhibitors of human immunodeficiency virus, type 1 (HIV-1) have been the focus of much recent research. C34, a potent fusion inhibitor derived from the HR2 region of gp41, was engineered into a 1:1 human serum albumin conjugate through stable c
Autor:
Jeff E. Mold, Jakob Michaëlsson, Jose M. Rivera, Kenneth I. Weinberg, Sofiya A. Galkina, Trevor D. Burt, Cheryl A. Stoddart, Joseph M. McCune, Shivkumar Venkatasubrahmanyam
Publikováno v:
Science (New York, N.Y.). 330(6011)
Lymphocytes Layer It On Cells of the immune system begin to develop from hematopoietic stem cells (HSCs) during fetal life. In the adult, HSCs continue to produce immune cells to replenish dying cells or in response to an infection. In mice and birds
Autor:
Barbara Sloan, Jose M. Rivera, Cheryl A. Bales, Mary E. Moreno, April N. Kinkade, Sofiya A. Galkina, Cheryl A. Stoddart, Rollie Ronquillo, George Chkhenkeli, Paul L. Black, Jennifer C. Bare
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e655 (2007)
PloS one, vol 2, iss 7
PLoS ONE
PloS one, vol 2, iss 7
PLoS ONE
Background The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antire