Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sofie Slott"'
Autor:
Pilar Fajardo, Maria Taskova, Miguel A. Martín‐Serrano, Jonas Hansen, Sofie Slott, Anna K. Jakobsen, Marie‐Louise Wibom, Beñat Salegi, Alberto Muñoz, Antonio Barbachano, Arpita Sharma, John Mark Gubatan, Aida Habtezion, Juan J. Sanz‐Ezquerro, Kira Astakhova, Ana Cuenda
Publikováno v:
Cancer Communications, Vol 42, Iss 9, Pp 897-901 (2022)
Externí odkaz:
https://doaj.org/article/a7065beb09cb43beb296317132b4f864
Autor:
Sofie Slott, Cecilie Schiøth Krüger-Jensen, Izabela Ferreira da Silva, Nadia Bom Pedersen, Kira Astakhova
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289556 (2023)
We describe a quantitative detection method for mutated microRNA in human plasma samples. Specific oligonucleotides designed from a Peyrard-Bishop model allowed accurate prediction of target:probe recognition affinity and specificity. Our amplificati
Externí odkaz:
https://doaj.org/article/f7308eebae174602bdb977cb1ba29037
Autor:
Roslyn M. Ray, Anders Højgaard Hansen, Sofie Slott, Maria Taskova, Kira Astakhova, Kevin V. Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 264-276 (2019)
Hypercholesterolemia is a condition that is characterized by very high levels of cholesterol in the blood and is a major correlating factor with heart disease. Indeed, high levels of the low-density lipoprotein (LDL) have been causally linked to the
Externí odkaz:
https://doaj.org/article/6e15e8f536754b36bb7603f65977608f
Autor:
Camilla Kofoed Andersen, Sangita Khatri, Jonas Hansen, Sofie Slott, Rohith Pavan Parvathaneni, Ana C. Mendes, Ioannis S. Chronakis, Shu-Chen Hung, Narendiran Rajasekaran, Zhuoran Ma, Shoujun Zhu, Hongjie Dai, Elizabeth D. Mellins, Kira Astakhova
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 453 (2021)
Two types of single-walled carbon nanotubes (SWCNTs), HiPco- and carboxyl-SWCNT, are evaluated as drug carriers for the traditional anti-inflammatory drug methotrexate (MTX) and a small interfering RNA (siRNA) targeting NOTCH1 gene. The nanotubes are
Externí odkaz:
https://doaj.org/article/745be840b5eb4af9bd57bb5d20ab58de
Autor:
Anders Højgaard Hansen, Maja van Hees, Hanlee P. Ji, Kira Astakhova, Heon Seok Kim, Sofie Slott
Publikováno v:
Mol Ther
van Hees, M, Slott, S, Hansen, A H, Kim, H S, Ji, H P & Astakhova, K 2022, ' New Approaches to Moderate CRISPR-Cas9 Activity : Addressing Issues of Cellular Uptake and Endosomal Escape ', Molecular Therapy, vol. 30, no. 1, pp. 32-46 . https://doi.org/10.1016/j.ymthe.2021.06.003
van Hees, M, Slott, S, Hansen, A H, Kim, H S, Ji, H P & Astakhova, K 2022, ' New Approaches to Moderate CRISPR-Cas9 Activity : Addressing Issues of Cellular Uptake and Endosomal Escape ', Molecular Therapy, vol. 30, no. 1, pp. 32-46 . https://doi.org/10.1016/j.ymthe.2021.06.003
CRISPR-Cas9 is rapidly entering molecular biology and biomedicine as a promising gene-editing tool. A unique feature of CRISPR-Cas9 is a single guide RNA directing a Cas9 nuclease towards its genomic target. Herein, we highlight new approaches for im
Publikováno v:
Biophysical Chemistry. 294:106949
Publikováno v:
Journal of chemical information and modeling. 61(7)
The use of mesoscopic models to describe the thermodynamic properties of locked nucleic acid (LNA)-modified nucleotides can provide useful insights into their properties, such as hydrogen-bonding and stacking interactions. In addition, the mesoscopic
Autor:
Kira Astakhova, Sofie Slott, Roslyn M. Ray, Maria Taskova, Kevin V. Morris, Anders Højgaard Hansen
Publikováno v:
Ray, R M, Hansen, A H, Slott, S, Taskova, M, Astakhova, K & Morris, K V 2019, ' Control of LDL Uptake in Human Cells by Targeting the LDLR Regulatory Long Non-coding RNA BM450697 ', Molecular Therapy-Nucleic Acids, vol. 17, pp. 264-276 . https://doi.org/10.1016/j.omtn.2019.05.024
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 264-276 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 264-276 (2019)
Hypercholesterolemia is a condition that is characterized by very high levels of cholesterol in the blood and is a major correlating factor with heart disease. Indeed, high levels of the low-density lipoprotein (LDL) have been causally linked to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d5e8555218be2b256449476c68531f
https://orbit.dtu.dk/en/publications/fb7933de-1439-488b-b88b-44711776e855
https://orbit.dtu.dk/en/publications/fb7933de-1439-488b-b88b-44711776e855
Autor:
Norman K. Fry, Jens Ø. Duus, Ian C. Skovsted, Sofie Slott, Georgia Kapatai, Christian Kjeldsen, Pernille L. Elverdal, Carmen L. Sheppard
Publikováno v:
Kjeldsen, C, Slott, S, Elverdal, P L, Sheppard, C L, Kapatai, G, Fry, N K, Skovsted, I C & Duus, J Ø 2018, ' Discovery and description of a new serogroup 7 Streptococcus pneumoniae serotype, 7D, and structural analysis of 7C and 7D ', Carbohydrate Research, vol. 463, pp. 24-31 . https://doi.org/10.1016/j.carres.2018.04.011
Streptococcus pneumoniae is characterised into 92 serotypes based on antigenic reactions of commercial rabbit sera to the capsular polysaccharides. During development of a bioinformatic serotyping tool (PneumoCaT), an isolate exhibited a novel codon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f181c58b9f799b248fcb365ebeae7764
https://orbit.dtu.dk/en/publications/7841ece3-7063-4618-863e-fe494be72d70
https://orbit.dtu.dk/en/publications/7841ece3-7063-4618-863e-fe494be72d70