Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Sofie R Salama"'
Autor:
Jacob Pfeil, Lauren M Sanders, Ioannis Anastopoulos, A Geoffrey Lyle, Alana S Weinstein, Yuanqing Xue, Andrew Blair, Holly C Beale, Alex Lee, Stanley G Leung, Phuong T Dinh, Avanthi Tayi Shah, Marcus R Breese, W Patrick Devine, Isabel Bjork, Sofie R Salama, E Alejandro Sweet-Cordero, David Haussler, Olena Morozova Vaske
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007753 (2020)
Precision oncology has primarily relied on coding mutations as biomarkers of response to therapies. While transcriptome analysis can provide valuable information, incorporation into workflows has been difficult. For example, the relative rather than
Externí odkaz:
https://doaj.org/article/6b18e66d017444afb3146ec81d8a8f6f
Autor:
Courtney S Onodera, Jason G Underwood, Sol Katzman, Frank Jacobs, David Greenberg, Sofie R Salama, David Haussler
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43511 (2012)
Enhancers and antisense RNAs play key roles in transcriptional regulation through differing mechanisms. Recent studies have demonstrated that enhancers are often associated with non-coding RNAs (ncRNAs), yet the functional role of these enhancer:ncRN
Externí odkaz:
https://doaj.org/article/4d3cf6302d75482b8f3b56f50be2b631
Publikováno v:
PLoS Genetics, Vol 6, Iss 5, p e1000960 (2010)
Regions of the genome that have been the target of positive selection specifically along the human lineage are of special importance in human biology. We used high throughput sequencing combined with methods to enrich human genomic samples for partic
Externí odkaz:
https://doaj.org/article/a3d4dd48f78249b4ae75a3acccfa1512
Autor:
Victoria T. Ly, Drew Ehrlich, Jess Sevetson, Ryan N. Hoffman, Sofie R. Salama, Sri Kurniawan, Mircea Teodorescu
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30469- (2024)
Working in a stem cell laboratory necessitates a thorough understanding of complex cell culture protocols, the operation of sensitive scientific equipment, adherence to safety standards, and general laboratory etiquette. For novice student researcher
Externí odkaz:
https://doaj.org/article/08275e05ee314374b44c59d9dcc7be38
Autor:
Katherine S Pollard, Sofie R Salama, Bryan King, Andrew D Kern, Tim Dreszer, Sol Katzman, Adam Siepel, Jakob S Pedersen, Gill Bejerano, Robert Baertsch, Kate R Rosenbloom, Jim Kent, David Haussler
Publikováno v:
PLoS Genetics, Vol 2, Iss 10, p e168 (2006)
Comparative genomics allow us to search the human genome for segments that were extensively changed in the last approximately 5 million years since divergence from our common ancestor with chimpanzee, but are highly conserved in other species and thu
Externí odkaz:
https://doaj.org/article/1e77ffc227fb46718fb747ad9c94fdf4
Autor:
Jason D. Fernandes, Armando Zamudio-Hurtado, Hiram Clawson, W. James Kent, David Haussler, Sofie R. Salama, Maximilian Haeussler
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Nearly half the human genome consists of repeat elements, most of which are retrotransposons, and many of which play important biological roles. However repeat elements pose several unique challenges to current bioinformatic analy
Externí odkaz:
https://doaj.org/article/57d4074818574439ab6825cf48f69a28
Autor:
Andrew R. Field, Frank M.J. Jacobs, Ian T. Fiddes, Alex P.R. Phillips, Andrea M. Reyes-Ortiz, Erin LaMontagne, Lila Whitehead, Vincent Meng, Jimi L. Rosenkrantz, Mari Olsen, Max Hauessler, Sol Katzman, Sofie R. Salama, David Haussler
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 245-257 (2019)
Summary: The cerebral cortex has expanded in size and complexity in primates, yet the molecular innovations that enabled primate-specific brain attributes remain obscure. We generated cerebral cortex organoids from human, chimpanzee, orangutan, and r
Externí odkaz:
https://doaj.org/article/653ace07a891481cab4cf66cb5212fa5
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Somatic mutations in cancers affecting protein coding genes can give rise to potentially therapeutic neoepitopes. These neoepitopes can guide Adoptive Cell Therapies and Peptide- and RNA-based Neoepitope Vaccines to selectively target tumor cells usi
Externí odkaz:
https://doaj.org/article/be19859171104a01a0a1923e6cbf455e
Autor:
Camila Ferreira de Souza, Thais S. Sabedot, Tathiane M. Malta, Lindsay Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder, Ana deCarvalho, Zachary Sanborn, Kerrie L. McDonald, William A. Friedman, Daniela Tirapelli, Laila Poisson, Tom Mikkelsen, Carlos G. Carlotti, Jr., Steven Kalkanis, Jean Zenklusen, Sofie R. Salama, Jill S. Barnholtz-Sloan, Houtan Noushmehr
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 637-651 (2018)
Summary: Glioma diagnosis is based on histomorphology and grading; however, such classification does not have predictive clinical outcome after glioblastomas have developed. To date, no bona fide biomarkers that significantly translate into a surviva
Externí odkaz:
https://doaj.org/article/706cab09ad454b2da0b587fe71e18729
Autor:
Joshua M. Stuart, Olena Morozova, David Haussler, Theodore C. Goldstein, Manu Chopra, Kyle Ellrott, Sofie R. Salama, Robert Baertsch, Alana S. Weinstein, Kiley Graim, Sahil Chopra, Duncan C. McColl, Teresa Swatloski, Adam M. Novak, Yulia Newton
Enrichment of Immune signaling in the integrated pan-cancer cluster. Different level of evidence support the association of the integrated pan-cancer cluster with an immune phenotype. (A) Enrichment of T- and B-cell signaling shown on the integrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033f5c5991b186b598f5290a611e375a
https://doi.org/10.1158/0008-5472.22419030
https://doi.org/10.1158/0008-5472.22419030
