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pro vyhledávání: '"Sofie Pattyn"'
Autor:
Robin E. Walsh, Angela Nix, Chloé Ackaert, Aurélie Mazy, Jana Schockaert, Sofie Pattyn, Laurent Malherbe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
T-cell dependent antibody responses to biotherapeutics remain a challenge to the optimal clinical application of biotherapeutics because of their capacity to impair drug efficacy and their potential to cause safety issues. To minimize this clinical i
Externí odkaz:
https://doaj.org/article/187dcf06803947fba4abb18ce530283f
Publikováno v:
Cancer Research. 83:5662-5662
Bispecifics targeting multiple antigens or epitopes have been showing great promise for treatment of cancer. However, managing unwanted immunogenicity has become a challenge in the development cycle of these promising therapeutics as there is a trend
Publikováno v:
Cancer Research. 83:5146-5146
Neutrophils have shown a lot of plasticity with important consequences on cancer disease progression and have been associated with multiple functions such as killing antibody-opsonized cancer cells, directly kill tumor cells through the release of re
Publikováno v:
Cancer Research. 83:5168-5168
The increasing interest in the tumor microenvironment leads to a focus on new bioassays to represent all the players of the cancer immune response. Some of these players like regulatory T cells play an important role by downregulating the anti-tumor