Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sofie Mellberg"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24887 (2011)
Angiogenesis is important for many physiological processes, diseases, and also regenerative medicine. Therapies that inhibit the vascular endothelial growth factor (VEGF) pathway have been used in the clinic for cancer and macular degeneration. In ca
Externí odkaz:
https://doaj.org/article/bb3d730f2cbf4ad4ae340513a9e78327
Autor:
Erik G. Larsson, Sofie Mellberg, Hua Huang, Martin Teichert, Patrik Georgii-Hemming, Irina Alafuzoff, Hellmut G. Augustin, Lei Zhang, Agata Zieba, Grietje Molema, Anna Dimberg, Elise Langenkamp, Henriikka Salomäki, Fredrik Pontén, Theo F. J. Kraus, Per Henrik Edqvist, Lothar C. Dieterich, Tommie Olofsson, Ola Söderberg
Publikováno v:
The Journal of Pathology. 228:378-390
Glioblastoma are aggressive astrocytic brain tumours characterized by microvascular proliferation and an abnormal vasculature, giving rise to brain oedema and increased patient morbidity. Here, we ...
Publikováno v:
Blood. 110:4214-4222
The role of fibroblast growth factors (FGFs) in blood vessel formation has remained unclear. We used differentiating stem-cell cultures (embryoid bodies) and teratomas to show that FGF receptor-1 (FGFR-1) exerts a negative regulatory effect on endoth
Autor:
Emma Rennel, Adam Ameur, Philippe Lassalle, Jan Komorowski, Pär Gerwins, Jakub Orzechowski Westholm, Michael J. Cross, Sofie Mellberg, Johan Botling, Ludvig Petersson, Anna Dimberg
Publikováno v:
Experimental Cell Research. 313:1285-1294
An in vitro model of VEGF-A-induced angiogenesis was used to generate transcription profiles of human microvascular endothelial cells. Microarray analysis showed increased transcription of genes known to regulate angiogenesis, but also genes that pre
Autor:
Lothar C, Dieterich, Sofie, Mellberg, Elise, Langenkamp, Lei, Zhang, Agata, Zieba, Henriikka, Salomäki, Martin, Teichert, Hua, Huang, Per-Henrik, Edqvist, Theo, Kraus, Hellmut G, Augustin, Tommie, Olofsson, Erik, Larsson, Ola, Söderberg, Grietje, Molema, Fredrik, Pontén, Patrik, Georgii-Hemming, Irina, Alafuzoff, Anna, Dimberg
Publikováno v:
The Journal of pathology. 228(3)
Glioblastoma are aggressive astrocytic brain tumours characterized by microvascular proliferation and an abnormal vasculature, giving rise to brain oedema and increased patient morbidity. Here, we have characterized the transcriptome of tumour-associ
Autor:
Emma Rennel, Anna Dimberg, Makoto Hayashi, Lena Claesson-Welsh, Per Lindahl, Fuad Bahram, Michael J. Cross, Erik Larsson, Sofie Mellberg, Adam Ameur, Jakub Orzechowski Westholm
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(5)
To define molecular events accompanying formation of the 3-dimensional (3D) vascular tube, we have characterized gene expression during vascular endothelial growth factor (VEGF)-induced tubular morphogenesis of endothelial cells. Microarray analyses
Autor:
Carina Hellberg, Dietmar Vestweber, Heinz-Georg Belting, Makoto Hayashi, Sofie Mellberg, Markus Affolter, Gou Young Koh, Jeremy Adler, Simona Vertuani, Lars Holmgren, Xiujuan Li, Arindam Majumdar, Zuyue Sun, Anna Dimberg, Lena Claesson-Welsh, Sina Koch, Elisabetta Dejana, Gavin Thurston
Publikováno v:
Nature communications
Nature Communications
Nature Communications
Vascular endothelial growth factor (VEGF) guides the path of new vessel sprouts by inducing VEGF receptor-2 activity in the sprout tip. In the stalk cells of the sprout, VEGF receptor-2 activity is downregulated. Here, we show that VEGF receptor-2 in
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24887 (2011)
PLoS ONE
PLoS ONE
Angiogenesis is important for many physiological processes, diseases, and also regenerative medicine. Therapies that inhibit the vascular endothelial growth factor (VEGF) pathway have been used in the clinic for cancer and macular degeneration. In ca