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UNSTRUCTURED The COVID-19 pandemic has generated unprecedented and sustained health management challenges worldwide. Health care systems continue to struggle to support the needs of the majority of infected individuals that are either asymptomatic or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b47e174a5c047e58c7a49a76cb6876e
https://doi.org/10.2196/preprints.25021
https://doi.org/10.2196/preprints.25021
Publikováno v:
JMIR mHealth and uHealth, Vol 9, Iss 6, p e25021 (2021)
JMIR mHealth and uHealth
JMIR mHealth and uHealth
The COVID-19 pandemic has generated unprecedented and sustained health management challenges worldwide. Health care systems continue to struggle to support the needs of the majority of infected individuals that are either asymptomatic or have mild sy
Autor:
Peter Stanley, Sarah Louise Dombernowsky, Christopher J. Tape, Marton Fogarasi, Willem H. Ouwehand, Sofie H. Willems, Gillian Murphy, John McCafferty
Publikováno v:
Proceedings of the National Academy of Sciences. 108:5578-5583
Proteolytic release from the cell surface is an essential activation event for many growth factors and cytokines. TNF-α converting enzyme (TACE) is a membrane-bound metalloprotease responsible for solubilizing many pathologically significant membran
Autor:
Gillian Murphy, Peter Stanley, Christopher J. Tape, David E. Neal, Sofie H. Willems, Ian G. Mills, John McCafferty, Neil A Taylor
Publikováno v:
Biochemical Journal. 428:439-450
ADAM17 (where ADAM is ‘a disintegrin and metalloproteinase’) can rapidly modulate cell-surface signalling events by the proteolytic release of soluble forms of proligands for cellular receptors. Many regulatory pathways affect the ADAM17 sheddase
Autor:
Judith Jans, Jessica H. van Dijk, Susanne van Schelven, Petra van der Groep, Sofie H. Willems, Trudy N. Jonges, Paul J. van Diest, J.L.H. Ruud Bosch
Publikováno v:
Urology. 75(4)
To uncover novel biomarkers that will help predict which patients are at risk and may guide future treatment decisions. A significant proportion of prostate cancer patients treated with radical prostatectomy will experience a recurrence of the diseas
Autor:
J.L.H. Ruud Bosch, Jessica H. van Dijk, Judith J.M. Jans, Petra van der Groep, Paul J. van Diest, Susanne J. van Schelven, Trudy N. Jonges, Sofie H. Willems
Publikováno v:
Journal of Urology. 181:99-99
Objectives To uncover novel biomarkers that will help predict which patients are at risk and may guide future treatment decisions. A significant proportion of prostate cancer patients treated with radical prostatectomy will experience a recurrence of
Autor:
Sofie H. Willems, Christopher J. Tape, Peter L. Stanley, Neil A. Taylor, Ian G. Mills, David E. Neal, John McCafferty, Gillian Murphy
Publikováno v:
Biochemical Journal; May2010, Vol. 428 Issue 3, p439-450, 12p