Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Sofie Degerman"'
Autor:
Olivia Carlund, Elina Thörn, Pia Osterman, Maja Fors, Andy Dernstedt, Mattias N. E. Forsell, Martin Erlanson, Mattias Landfors, Sofie Degerman, Magnus Hultdin
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Large B-cell lymphoma (LBCL) is the most common lymphoma and is known to be a biologically heterogeneous disease regarding genetic, phenotypic, and clinical features. Although the prognosis is good, one-third has a primary refract
Externí odkaz:
https://doaj.org/article/56b7f9f5bdc94255b44d101ecad34ca6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Telomere Biology Disorders (TBDs) are characterized by mutations in telomere-related genes leading to short telomeres and premature aging but with no strict correlation between telomere length and disease severity. Epigenetic alterations are
Externí odkaz:
https://doaj.org/article/2ac22372455e4617987a1b63be9530ff
Autor:
Fernanda Schäfer Hackenhaar, Maria Josefsson, Annelie Nordin Adolfsson, Mattias Landfors, Karolina Kauppi, Magnus Hultdin, Rolf Adolfsson, Sofie Degerman, Sara Pudas
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/83fc6239bff440109e855e934df6b2d9
Autor:
Fernanda Schäfer Hackenhaar, Maria Josefsson, Annelie Nordin Adolfsson, Mattias Landfors, Karolina Kauppi, Magnus Hultdin, Rolf Adolfsson, Sofie Degerman, Sara Pudas
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Leukocyte telomere length (LTL) has been shown to predict Alzheimer’s disease (AD), albeit inconsistently. Failing to account for the competing risks between AD, other dementia types, and mortality, can be an explanation for the
Externí odkaz:
https://doaj.org/article/1f2e6278a7284fb18885a7a88c737b8d
Autor:
Emma Andersson-Evelönn, Linda Vidman, David Källberg, Mattias Landfors, Xijia Liu, Börje Ljungberg, Magnus Hultdin, Patrik Rydén, Sofie Degerman
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Metastasized clear cell renal cell carcinoma (ccRCC) is associated with a poor prognosis. Almost one-third of patients with non-metastatic tumors at diagnosis will later progress with metastatic disease. These patients need to be
Externí odkaz:
https://doaj.org/article/f5fbdd0116604a7abc2d90894b681e66
Autor:
Emma Andersson Evelönn, Mattias Landfors, Zahra Haider, Linda Köhn, Börje Ljungberg, Göran Roos, Sofie Degerman
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype among renal cancer and is associated with poor prognosis if metastasized. Up to one third of patients with local disease at diagnosis will develop metastasis after
Externí odkaz:
https://doaj.org/article/626555fd16db4c3da9426faa2dd9d8d9
Autor:
Luca Trotta, Anna Norberg, Mervi Taskinen, Vivien Béziat, Sofie Degerman, Ulla Wartiovaara-Kautto, Hannamari Välimaa, Kirsi Jahnukainen, Jean-Laurent Casanova, Mikko Seppänen, Janna Saarela, Minna Koskenvuo, Timi Martelius
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Background The telomere biology disorders (TBDs) include a range of multisystem diseases characterized by mucocutaneous symptoms and bone marrow failure. In dyskeratosis congenita (DKC), the clinical features of TBDs stem from the depletion
Externí odkaz:
https://doaj.org/article/d877411b75874771a7bb8c318f40058e
Autor:
Magnus Borssén, Jessica Nordlund, Zahra Haider, Mattias Landfors, Pär Larsson, Jukka Kanerva, Kjeld Schmiegelow, Trond Flaegstad, Ólafur Gísli Jónsson, Britt-Marie Frost, Josefine Palle, Erik Forestier, Mats Heyman, Magnus Hultdin, Gudmar Lönnerholm, Sofie Degerman
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-7 (2018)
Abstract Background Few biological markers are associated with survival after relapse of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In pediatric T-cell ALL, we have identified promoter-associated methylation alterations that correlate w
Externí odkaz:
https://doaj.org/article/a8a4c8a2feda4e9c8f3b60d595b82ab8
Autor:
Ewa Henckel, Anna James, Jon R Konradsen, Björn Nordlund, Malin Kjellberg, Eva Berggren-Broström, Gunilla Hedlin, Sofie Degerman, Kajsa Bohlin
Publikováno v:
Children, Vol 8, Iss 2, p 80 (2021)
Extremely preterm infants are born with immature lungs and are exposed to an inflammatory environment as a result of oxidative stress. This may lead to airway remodeling, cellular aging and the development of bronchopulmonary dysplasia (BPD). Reliabl
Externí odkaz:
https://doaj.org/article/4e70c6a8ad614265abb38d9ff9f6f4d3
Autor:
Sofie Degerman, Mattias Landfors, Jan Konrad Siwicki, John Revie, Magnus Borssén, Emma Evelönn, Erik Forestier, Krystyna H. Chrzanowska, Patrik Rydén, W. Nicol Keith, Göran Roos
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 606-615 (2014)
We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same model to investi
Externí odkaz:
https://doaj.org/article/45a9461da5ed43f1b09b8e7969e6aabe