Výsledky vyhledávání - "Sofie Beckers"

LRRC37B Is a Species-Specific Regulator of Voltage-Gated Channels and Excitability in Human Cortical Neurons

Autor: Baptiste Libé-Philippot, Amélie Lejeune, Keimpe Wierda, Ine Vlaeminck, Sofie Beckers, Vaiva Gaspariunaite, Angéline Bilheu, Hajnalka Nyitrai, Kristel M. Vennekens, Thomas W. Bird, Daniela Soto, Megan Y Dennis, Davide Comoletti, Tom Theys, Joris de Wit, Pierre Vanderhaeghen

Publikováno v: SSRN Electronic Journal.

The enhanced cognitive abilities characterizing the human species result from specialized features of neurons and circuits, but the underlying molecular mechanisms remain largely unknown. Here we report that the hominid-specific geneLRRC37Bencodes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abc6c8dbdd2522ec871469bfd57f8ea
https://doi.org/10.2139/ssrn.4309022

Zobrazit plný text záznamu

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors

Autor: Roxane Van Heurck, Jérôme Bonnefont, Marta Wojno, Ikuo K. Suzuki, Fausto D. Velez-Bravo, Emir Erkol, Dan Truc Nguyen, Adèle Herpoel, Angéline Bilheu, Sofie Beckers, Catherine Ledent, Pierre Vanderhaeghen

Publikováno v: Neuron. 111:65-80.e6

The primary cilium is a central signaling component during embryonic development. Here we focus on CROCCP2, a hominid-specific gene duplicate from ciliary rootlet coiled coil (CROCC), also known as rootletin, that encodes the major component of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed393b801a485202002b6997f139bb6
https://doi.org/10.1016/j.neuron.2022.10.018

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání