Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sofie, Van Gassen"'
Autor:
Thomas Liechti, Sofie Van Gassen, Margaret Beddall, Reid Ballard, Yaser Iftikhar, Renguang Du, Thiagarajan Venkataraman, David Novak, Massimo Mangino, Stephen Perfetto, H. Benjamin Larman, Tim Spector, Yvan Saeys, Mario Roederer
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100619- (2023)
Summary: High-dimensional flow cytometry is the gold standard to study the human immune system in large cohorts. However, large sample sizes increase inter-experimental variation because of technical and experimental inaccuracies introduced by batch
Externí odkaz:
https://doaj.org/article/2e8e1fccf31b420da4db9601aa01dcf0
Autor:
Nadine L de Boer, Job P van Kooten, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Marcella Willemsen, Michelle V Dietz, Katrien L A Quintelier, Madelief Vink, Yvan Saeys, Sofie Van Gassen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Malignant peritoneal mesothelioma (MPM) is an aggressive malignancy with a poor prognosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival outcomes, but recurrence rates remain high. Dend
Externí odkaz:
https://doaj.org/article/4969d9c96188451cb2fee28a466fa4a5
Autor:
Paulina Rybakowska, Sofie Van Gassen, Jordi Martorell Marugán, Katrien Quintelier, Yvan Saeys, Marta E. Alarcón-Riquelme, Concepción Marañón
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101697- (2022)
Summary: Mass cytometry (MC) is a powerful large-scale immune monitoring technology. To maximize MC data quality, we present a protocol for whole blood analysis together with an R package, Cyto Quality Pipeline (CytoQP), which minimizes the experimen
Externí odkaz:
https://doaj.org/article/81ad41cd80a7464e8524664f1024f0ed
Autor:
Jana Neirinck, Annelies Emmaneel, Malicorne Buysse, Jan Philippé, Sofie Van Gassen, Yvan Saeys, Xavier Bossuyt, Stefanie De Buyser, Mirjam van der Burg, Martín Pérez-Andrés, Alberto Orfao, Jacques J. M. van Dongen, Bart N. Lambrecht, Tessa Kerre, Mattias Hofmans, Filomeen Haerynck, Carolien Bonroy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionMultiparameter flow cytometry (FCM) immunophenotyping is an important tool in the diagnostic screening and classification of primary immunodeficiencies (PIDs). The EuroFlow Consortium recently developed the PID Orientation Tube (PIDOT) as
Externí odkaz:
https://doaj.org/article/efebbf6d130f4647ae0f5f8bb4612a85
Autor:
Paulina Rybakowska, Sofie Van Gassen, Katrien Quintelier, Yvan Saeys, Marta E. Alarcón-Riquelme, Concepción Marañón
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3160-3175 (2021)
Mass cytometry is a powerful tool for deep immune monitoring studies. To ensure maximal data quality, a careful experimental and analytical design is required. However even in well-controlled experiments variability caused by either operator or instr
Externí odkaz:
https://doaj.org/article/bad856511dea41bc8fe3b81b0781eae7
Autor:
Koen Venken, Peggy Jacques, Céline Mortier, Mark E. Labadia, Tine Decruy, Julie Coudenys, Kathleen Hoyt, Anita L. Wayne, Robert Hughes, Michael Turner, Sofie Van Gassen, Liesbet Martens, Dustin Smith, Christian Harcken, Joseph Wahle, Chao-Ting Wang, Eveline Verheugen, Nadia Schryvers, Gaëlle Varkas, Heleen Cypers, Ruth Wittoek, Yves Piette, Lieve Gyselbrecht, Serge Van Calenbergh, Filip Van den Bosch, Yvan Saeys, Gerald Nabozny, Dirk Elewaut
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The role of innate T cell subsets in the pathogenesis of spondyloarthritis (SpA) is not well understood. Here, the authors examine the role of invariant natural killer T (iNKT) and γδ-T cells in SpA and show that disease-derived iNKT and γδ-T cel
Externí odkaz:
https://doaj.org/article/ddd72678135941fdb84362715749b1f1
Autor:
Srinath Govindarajan, Djoere Gaublomme, Renée Van der Cruyssen, Eveline Verheugen, Sofie Van Gassen, Yvan Saeys, Simon Tavernier, Takao Iwawaki, Yehudi Bloch, Savvas. N. Savvides, Bart N. Lambrecht, Sophie Janssens, Dirk Elewaut, Michael B. Drennan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Invariant natural killer T (iNKT) cells rapidly enhance cytokine secretion and effector function following activation, but the underlying mechanism is still unclear. Here the authors show that an endoplasmic reticulum stress sensor, inositol-requirin
Externí odkaz:
https://doaj.org/article/b6d32051b63e4b37881f01ffdff4d01b
Autor:
Margot F. van Spronsen, Sophie Horrevorts, Claudia Cali, Theresia M. Westers, Sofie Van Gassen, Yvan Saeys, Sandra J. van Vliet, Yvette van Kooyk, Arjan A. van de Loosdrecht
Publikováno v:
van Spronsen, M F, Horrevorts, S, Cali, C, Westers, T M, van Gassen, S, Saeys, Y, van Vliet, S J, van Kooyk, Y & van de Loosdrecht, A A 2023, ' Dysregulation of developmental and cell type-specific expression of glycoconjugates on hematopoietic cells : a new characteristic of myelodysplastic neoplasms (MDS) ', Leukemia, vol. 37, no. 3, pp. 702-707 . https://doi.org/10.1038/s41375-022-01784-x
Leukemia, 37(3), 702-707. Nature Publishing Group
Leukemia, 37(3), 702-707. Nature Publishing Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0a688d77e8026d57b7c2bc7fffcfb4
https://doi.org/10.1038/s41375-022-01784-x
https://doi.org/10.1038/s41375-022-01784-x
Autor:
Annelies Emmaneel, Delfien J. Bogaert, Sofie Van Gassen, Simon J. Tavernier, Melissa Dullaers, Filomeen Haerynck, Yvan Saeys
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses cause
Externí odkaz:
https://doaj.org/article/a959fc49fb094dddbdb6939d452789f2
Autor:
Victor Bosteels, Sandra Maréchal, Clint De Nolf, Sofie Rennen, Jonathan Maelfait, Simon J. Tavernier, Jessica Vetters, Evelien Van De Velde, Farzaneh Fayazpour, Kim Deswarte, Alexander Lamoot, Julie Van Duyse, Liesbet Martens, Cédric Bosteels, Ria Roelandt, Annelies Emmaneel, Sofie Van Gassen, Louis Boon, Gert Van Isterdael, Isabelle Guillas, Niels Vandamme, Doris Höglinger, Bruno G. De Geest, Wilfried Le Goff, Yvan Saeys, Kodi S. Ravichandran, Bart N. Lambrecht, Sophie Janssens
Publikováno v:
Science immunology, 8(83):eadd3955. American Association for the Advancement of Science
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways driving immunogenic maturation in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec96cbb2f6bda51e969e5c6e579c2dd
http://www.scopus.com/inward/record.url?scp=85159738119&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85159738119&partnerID=8YFLogxK