Výsledky vyhledávání - "Sofia Zenelak"

Peripheral Tumor Necrosis Factor-Alpha (TNF-α) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice

Autor: Georgia-Ioanna Kartalou, Evi Paouri, Sofia Zenelak, Spiros Georgopoulos, Ourania Tzara

Publikováno v: The Journal of Neuroscience. 37:5155-5171

Increasing evidence has suggested that systemic inflammation along with local brain inflammation can play a significant role in Alzheimer's disease (AD) pathogenesis. Identifying key molecules that regulate the crosstalk between the immune and the CN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8495a27c5a0edc404d511efb008f3d03
https://doi.org/10.1523/jneurosci.2484-16.2017

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Genetic Deletion of Tumor Necrosis Factor-α Attenuates Amyloid-β Production and Decreases Amyloid Plaque Formation and Glial Response in the 5XFAD Model of Alzheimer's Disease

Autor: Ourania Tzara, Evi Paouri, Sofia Zenelak, Spiros Georgopoulos

Publikováno v: Journal of Alzheimer's disease : JAD. 60(1)

Increasing evidence suggests that neuroinflammation comprises a major characteristic of Alzheimer's disease (AD). Tumor necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine implicated in neurodegenerative diseases including AD, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71df02993dea76edec72876b019500c1
https://pubmed.ncbi.nlm.nih.gov/28826177

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