Antineoplastic activity of GP-2250 in-vitro and in mouse xenograft models.

Autor: Sofia RD; Head Nonclinical Research and Development Panavance Therapeutics., Martin KM; Head Scientific Communications and Regulatory Writing Panavance Therapeutics., Costin JC; Head Research and Development Panavance Therapeutics.

Publikováno v: Anti-cancer drugs [Anticancer Drugs] 2024 Feb 01; Vol. 35 (2), pp. 183-189. Date of Electronic Publication: 2023 Nov 21.

The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: a reactive metabolite in felbamate bioactivation

Autor: Christine M. Dieckhaus, Sofia Rd, Webster L. Santos, Timothy L. Macdonald

Publikováno v: Chemical research in toxicology. 14(8)

4-Hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one has been proposed to be a reactive metabolite of the anti-epileptic drug felbamate [Thompson et al. (1996) Chem. Res. Toxicol. 9, 1225-1229]. 4-Hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one exists in equilibr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299778dc87a58a72c5e75a20112cd32c
https://pubmed.ncbi.nlm.nih.gov/11511169

Method validation and characterization of stress degradation products of azelastine hydrochloride using LC-UV/PDA and LC-Q/TOF-MS studies.

Autor: Shekhar S; University Institute of Pharmaceutical Sciences, UGC Center of Advanced Study, Panjab University, Chandigarh, India., Bali A; University Institute of Pharmaceutical Sciences, UGC Center of Advanced Study, Panjab University, Chandigarh, India.

Publikováno v: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2024 Apr 15; Vol. 38 (7), pp. e9712.

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