Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sofia Nascimento, Dos Santos"'
Autor:
Sofia Nascimento dos Santos, Dino Seigo Gushiken Junior, Jhonatas Pedrosa Marim Pereira, Natália Miranda Iadocicco, André Henrique Silva, Tatielle do Nascimento, Luís Alberto Pereira Dias, Flávia Rodrigues de Oliveira Silva, Eduardo Ricci-Junior, Ralph Santos-Oliveira, Emerson Soares Bernardes
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Chemotherapy resistance remains a major cause of therapeutic failure in gastric cancer. The combination of genetic material such as interference RNAs (iRNAs) to silence cancer-associated genes with chemotherapeutics has become a novel approa
Externí odkaz:
https://doaj.org/article/715a75d2941d40169c1dce99e8e41936
Autor:
Martha Sahylí Ortega Pijeira, Sofia Nascimento dos Santos, Yasniel Babi Araujo, André Luis Lapolli, Marcio Nardelli Wandermuren, Zalua Rodríguez Riera, Ivone Carvalho, Philip H. Elsinga, Emerson Soares Bernardes
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Background 2-[18F]Fluoroethyltosylate ([18F]FEtOTs) is a well-known 18F-fluoroalkylating agent widely used to synthesize radiotracers for positron emission tomography. The widespread use of [18F]FEtOTs is due in part to its low volatility wh
Externí odkaz:
https://doaj.org/article/04c22e17462c451fab8351ae291c7c7b
Autor:
Arian Pérez Nario, Jenilee Woodfield, Sofia Nascimento dos Santos, Cody Bergman, Melinda Wuest, Yasniel Babí Araújo, André Luis Lapolli, Frederick G. West, Frank Wuest, Emerson Soares Bernardes
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Background Tissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission t
Externí odkaz:
https://doaj.org/article/7847c548591345c4b59d72e89074972b
Autor:
Carla Daruich de Souza, Angelica Bueno Barbezan, Wilmmer Alexander Arcos Rosero, Sofia Nascimento dos Santos, Diego Vergaças de Sousa Carvalho, Carlos Alberto Zeituni, Emerson Soares Bernardes, Daniel Perez Vieira, Patrick Jack Spencer, Martha Simões Ribeiro, Maria Elisa Chuery Martins Rostelato
Publikováno v:
Nanomaterials, Vol 12, Iss 2, p 187 (2022)
New forms of cancer treatment, which are effective, have simple manufacturing processes, and easily transportable, are of the utmost necessity. In this work, a methodology for the synthesis of radioactive Gold-198 nanoparticles without the use of sur
Externí odkaz:
https://doaj.org/article/8c0419ce9465414a8cb14bade277a833
Autor:
Felipe Leite de Oliveira, Sofia Nascimento dos Santos, Lauremilia Ricon, Thayse Pinheiro da Costa, Jonathas Xavier Pereira, Camila Brand, Marise Lopes Fermino, Roger Chammas, Emerson Soares Bernardes, Márcia Cury El-Cheikh
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Galectin-3 (Gal-3) is a β-galactoside binding protein that controls cell-cell and cell-extracellular matrix interactions. In lymphoid organs, gal-3 inhibits B cell differentiation by mechanisms poorly understood. The B cell development is d
Externí odkaz:
https://doaj.org/article/7dbf837b06cb45099ad95605f8e98fd6
Autor:
Huma Khan, Vaidehi Makwana, Sofia Nascimento dos Santos, Carlos Eduardo Bonacossa de Almeida, Ralph Santos-Oliveira, Sotiris Missailidis
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1239 (2021)
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem rep
Externí odkaz:
https://doaj.org/article/1692a653d37c475cbd96b20bd2ea2e5a
Autor:
Ana Cláudia Camargo Miranda, Sofia Nascimento dos Santos, Leonardo Lima Fuscaldi, Luiza Mascarenhas Balieiro, Maria Helena Bellini, Maria Inês Calil Cury Guimarães, Elaine Bortoleti de Araújo
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 971 (2021)
The oncogene HER2 is an important molecular target in oncology because it is associated with aggressive disease and the worst prognosis. The development of non-invasive imaging techniques and target therapies using monoclonal antibodies is a rapidly
Externí odkaz:
https://doaj.org/article/a8ede3f913484f6bb89211a3b305e2b4
Autor:
Martha Sahylí Ortega Pijeira, Paulo Sérgio Gonçalves Nunes, Sofia Nascimento dos Santos, Zhengxing Zhang, Arian Pérez Nario, Efrain Araujo Perini, Walter Miguel Turato, Zalua Rodríguez Riera, Roger Chammas, Philip H. Elsinga, Kuo-Shyan Lin, Ivone Carvalho, Emerson Soares Bernardes
Publikováno v:
Molecules, Vol 25, Iss 8, p 1872 (2020)
Losartan is widely used in clinics to treat cardiovascular related diseases by selectively blocking the angiotensin II type 1 receptors (AT1Rs), which regulate the renin-angiotensin system (RAS). Therefore, monitoring the physiological and pathologic
Externí odkaz:
https://doaj.org/article/9c81daf22cdc46fe97fc724b044dc784
Autor:
Marcelo Dias-Baruffi, Eduardo Ricci, Ralph Santos Oliveira, Camillo Del Cistia Andrade, Thais Canassa De Leo, Sofia Nascimento dos Santos, Norberto Peporine Lopes, Walter Miguel Turato, Emerson Soares Bernardes
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Galectin-3 (Gal-3) is a multifunctional glycan-binding protein that participates in many pathophysiological events and has been described as a biomarker and potential therapeutic target for severe disorders, such as cancer. Several probes for Gal-3 o
Autor:
Thais Canassa, De Leo, Sofia Nascimento, Dos Santos, Emerson Soares, Bernardes, Richard D, Cummings, Sean R, Stowell, Marcelo, Dias-Baruffi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2442
Molecular imaging (MI) is a non-invasive growing technology that allows the investigation of cellular and molecular processes in basic and clinical research and medicine. Luminescent proteins and radionuclides can be associated to target molecules pr