Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sofia N Moraes"'
Autor:
Sofia N Moraes, Jordan T Becker, Seyed Arad Moghadasi, Nadine M Shaban, Ashley A Auerbach, Adam Z Cheng, Reuben S Harris
Publikováno v:
eLife, Vol 11 (2022)
Viruses have evolved diverse mechanisms to antagonize host immunity such as direct inhibition and relocalization of cellular APOBEC3B (A3B) by the ribonucleotide reductase (RNR) of Epstein-Barr virus. Here, we investigate the mechanistic conservation
Externí odkaz:
https://doaj.org/article/62fa70d70b3b4647b32f816eb1942dd8
Autor:
Elisa Fanunza, Adam Z. Cheng, Ashley A. Auerbach, Bojana Stefanovska, Sofia N. Moraes, James R. Lokensgard, Matteo Biolatti, Valentina Dell’Oste, Craig J. Bierle, Wade A. Bresnahan, Reuben S. Harris
Publikováno v:
bioRxiv
The APOBEC3 family of DNA cytosine deaminases comprises an important arm of the innate antiviral defense system. The gamma-herpesviruses EBV and KSHV and the alpha-herpesviruses HSV-1 and HSV-2 have evolved an efficient mechanism to avoid APOBEC3 res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4827f89d6ee4da13c9d87ba7b7a4923
https://doi.org/10.1101/2023.01.30.526383
https://doi.org/10.1101/2023.01.30.526383
Autor:
Ashley A. Auerbach, Jordan T. Becker, Sofia N. Moraes, Seyed Arad Moghadasi, Jolene M. Duda, Daniel J. Salamango, Reuben S. Harris
Publikováno v:
mSphere.
APOBEC3B is an innate immune effector enzyme capable of introducing mutations in viral genomes through DNA cytosine-to-uracil editing. Recent studies have shown that gamma-herpesviruses, such as Epstein-Barr virus (EBV), have evolved a potent APOBEC3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5404907a7524683359ef14364cac6cdc
https://pubmed.ncbi.nlm.nih.gov/36374108
https://pubmed.ncbi.nlm.nih.gov/36374108
Autor:
Seyed Arad Moghadasi, Morgan A. Esler, Yuka Otsuka, Jordan T. Becker, Sofia N. Moraes, Constance B. Anderson, Srinivas Chamakuri, Christopher Belica, Chloe Wick, Daniel A. Harki, Damian W. Young, Louis Scampavia, Timothy P. Spicer, Ke Shi, Hideki Aihara, William L. Brown, Reuben S. Harris
Publikováno v:
mBio. 13
The main protease, M pro , of SARS-CoV-2 is an essential viral protein required for the earliest steps of infection. It is therefore an attractive target for antiviral drug development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::302d4a2d19f0186788d924b32a4becc9
https://doi.org/10.1128/mbio.00784-22
https://doi.org/10.1128/mbio.00784-22
Autor:
Sofia N. Moraes, Zhiheng Yu, Rui Yan, Ke Shi, Adam Z. Cheng, Michael A. Carpenter, Reuben S. Harris, Jason S. McLellan, Nadine M. Shaban
Viruses use a plethora of mechanisms to evade immune responses. A new example is neutralization of the nuclear DNA cytosine deaminase APOBEC3B by the Epstein-Barr virus (EBV) ribonucleotide reductase subunit BORF2. Cryo-EM studies of APOBEC3B-BORF2 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c1ff565839475d03b4e95fdcf5f86a3
https://doi.org/10.1101/2021.08.30.458246
https://doi.org/10.1101/2021.08.30.458246
Autor:
Adam Z. Cheng, Craig J. Bierle, Peter J. Southern, Reuben S. Harris, Nadine M. Shaban, Elisa Fanunza, Sofia N. Moraes, Wade A. Bresnahan, Stephen A. Rice
Publikováno v:
Viruses, Vol 13, Iss 390, p 390 (2021)
Viruses
Viruses
The apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) family of DNA cytosine deaminases provides a broad and overlapping defense against viral infections. Successful viral pathogens, by definition, have evolved strategies to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de5d6e7e2d9498fb4d6950c2759cc05
https://www.mdpi.com/1999-4915/13/3/390
https://www.mdpi.com/1999-4915/13/3/390