Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sofia Morfopoulou"'
Autor:
Sarah Buddle, Leysa Forrest, Naomi Akinsuyi, Luz Marina Martin Bernal, Tony Brooks, Cristina Venturini, Charles Miller, Julianne R. Brown, Nathaniel Storey, Laura Atkinson, Timothy Best, Sunando Roy, Sian Goldsworthy, Sergi Castellano, Peter Simmonds, Heli Harvala, Tanya Golubchik, Rachel Williams, Judith Breuer, Sofia Morfopoulou, Oscar Enrique Torres Montaguth
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Metagenomics is a powerful approach for the detection of unknown and novel pathogens. Workflows based on Illumina short-read sequencing are becoming established in diagnostic laboratories. However, high sequencing depth requiremen
Externí odkaz:
https://doaj.org/article/e2af225a703e4fe19e0e320c7515d0b3
Autor:
Laura Atkinson, Jack CD. Lee, Alexander Lennon, Divya Shah, Nathaniel Storey, Sofia Morfopoulou, Kathryn A. Harris, Judy Breuer, Julianne R. Brown
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19854- (2023)
Metagenomic next-generation sequencing (mNGS) is an untargeted technique capable of detecting all microbial nucleic acid within a sample. This protocol outlines our wet laboratory method for mNGS of cerebrospinal fluid (CSF) specimens and tissues fro
Externí odkaz:
https://doaj.org/article/382be6b51e724e0fab73da33306d5978
Autor:
Sina Rüeger, Christian Hammer, Alexis Loetscher, Paul J. McLaren, Dylan Lawless, Olivier Naret, Daniel P. Depledge, Sofia Morfopoulou, Judith Breuer, Evgeny Zdobnov, Jacques Fellay, the Swiss HIV Cohort Study
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Epstein–Barr virus (EBV) is one of the most common viruses latently infecting humans. Little is known about the impact of human genetic variation on the large inter-individual differences observed in response to EBV infection. To search fo
Externí odkaz:
https://doaj.org/article/6b142b84091a44b1a57768ff6d6d4c51
Autor:
Juanita Pang, Jennifer A Slyker, Sunando Roy, Josephine Bryant, Claire Atkinson, Juliana Cudini, Carey Farquhar, Paul Griffiths, James Kiarie, Sofia Morfopoulou, Alison C Roxby, Helena Tutil, Rachel Williams, Soren Gantt, Richard A Goldstein, Judith Breuer
Publikováno v:
eLife, Vol 9 (2020)
Cytomegalovirus (CMV) is the commonest cause of congenital infection and particularly so among infants born to HIV-infected women. Studies of congenital CMV infection (cCMVi) pathogenesis are complicated by the presence of multiple infecting maternal
Externí odkaz:
https://doaj.org/article/011a2173713447c88e52887e2c178a07
Author Correction: The influence of human genetic variation on Epstein–Barr virus sequence diversity
Autor:
Sina Rüeger, Christian Hammer, Alexis Loetscher, Paul J. McLaren, Dylan Lawless, Olivier Naret, Nina Khanna, Enos Bernasconi, Matthias Cavassini, Huldrych F. Günthard, Christian R. Kahlert, Andri Rauch, Daniel P. Depledge, Sofia Morfopoulou, Judith Breuer, Evgeny Zdobnov, Jacques Fellay, the Swiss HIV Cohort Study
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/ace188f75c0646de8eeaff7b032118a4
Autor:
Steve Pells, Eirini Koutsouraki, Sofia Morfopoulou, Sara Valencia-Cadavid, Simon R Tomlinson, Ravi Kalathur, Matthias E Futschik, Paul A De Sousa
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131102 (2015)
Human embryonic stem cells (hESCs) undergo epigenetic changes in vitro which may compromise function, so an epigenetic pluripotency "signature" would be invaluable for line validation. We assessed Cytosine-phosphate-Guanine Island (CGI) methylation i
Externí odkaz:
https://doaj.org/article/a23f5da6431c4b93b37c2f45b9627544
Autor:
Zainab Golwala, Jacob Simmonds, Anupama Rao, Jeffrey I. Cohen, Sofia Morfopoulou, Judith Breuer, Fanny Wegner, Tetsushi Yoshikawa, Austen Worth, Charlotte J. Houldcroft, Arina Lazareva, Cristina Venturini, Stephen D. Marks, Persis Amrolia, Paul J. Farrell
Publikováno v:
British Journal of Haematology
Summary Chronic active Epstein–Barr virus (CAEBV) disease is a rare condition characterised by persistent EBV infection in previously healthy individuals. Defective EBV genomes were found in East Asian patients with CAEBV. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daefd705cd1f9fb51569a09487ba6bd5
http://europepmc.org/articles/PMC8589012
http://europepmc.org/articles/PMC8589012
Autor:
Judith Breuer, Sofia Morfopoulou, Sarah Buddle, Oscar Torres Montaguth, Laura Atkinson, José Afonso Guerra-Assunção, Nathaniel Storey, Sunando Roy, Alexander Lennon, Jack Lee, Rachel Williams, Charlotte Williams, Helena Tutill, Nadua Bayzid, Luz Marina Martin Bernal, Catherine Moore, Kate Templeton, Matthew Holden, Priyen Shah, Samantha Cooray, Marie Voice, Michael Steele, Colin Fink, Thomas Whittaker, Giorgia Santilli, Paul Gissen, Rachel Brown, Benedikt Kaufer, Jana Reich, Julien Andreani, Peter Simmonds, Dimah Alrabiah, Sergi Castellano Hereza, Catarina Andrade, Glenn Anderson, Chayarani Kelgeri, Simon Waddington, Juan Antinao Diaz, James Hatcher, Surjo De, Riccardo Chiozzi, Konstantinos Thalassinos, Thomas Jacques, Katja Hoschler, Tiina Talts, Cristina Celma, Suam Gonzalez, Eileen Gallagher, Ruth Simmons, Conall Watson, Sema Mandal, Maria Zambon, Meera Chand, Luis Campos, Joanne Martin, Emma Thomson, Ines Ushiro-Lumb, Michael Levin, Julianne Brown
Since the first reports of hepatitis of unknown aetiology occurring in UK children, over 1000 cases have been reported worldwide, including 268 cases in the UK, with the majority younger than 6 years old. Using genomic, proteomic and immunohistochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d826e75a4aeab9e8e81abf2da21fe2
https://doi.org/10.21203/rs.3.rs-1895370/v1
https://doi.org/10.21203/rs.3.rs-1895370/v1
Autor:
Sofia Morfopoulou, Oscar Enrique Torres Montaguth, Nathaniel Storey, Conall Watson, Jack Lee, Sarah Buddle, Sergi Castellano, José Afonso Guerra-Assunção
SummarySince the first reports of hepatitis of unknown aetiology occurring in UK children, over 1000 cases have been reported worldwide, including 268 cases in the UK, with the majority younger than 6 years old. Using genomic, proteomic and immunohis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d503231aad18ff703ebec1302d46af3
https://doi.org/10.1101/2022.07.28.22277963
https://doi.org/10.1101/2022.07.28.22277963
Autor:
Guillaume Gricourt, Michael Huber, Martin Beer, Jutte J.C. de Vries, Jiabin Huang, Verena Kufner, Samuel Cordey, Julianne R Brown, Anna Papa, Dirk Hoeper, Bas B. Oude Munnink, Maryam Zaheri, Judith Breuer, Sofia Morfopoulou, F. Xavier López-Labrador, Els Keyaerts, Igor A. Sidorov, Jakub Kubacki, Nicole Fischer, Dennis Schmitz, Christophe Rodriguez, Claudia Bachofen, Florian Laubscher, Alihan Bulgurcu, Leen Beller, Aitana Lebrand, Eric C. J. Claas, Arzu Sayiner, Aloys C.M. Kroes, Sander van Boheemen
Metagenomic sequencing is increasingly being used in clinical settings for difficult to diagnose cases. The performance of viral metagenomic protocols relies to a large extent on the bioinformatic analysis. In this study, the European Society for Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e14bb59c1dadfc3b46086484682de6
https://doi.org/10.1101/2021.05.04.21256618
https://doi.org/10.1101/2021.05.04.21256618