Výsledky vyhledávání - "Sofia Manicka"

Akademický článek

Incidental germline findings during molecular profiling of tumor tissues for precision oncology: molecular survey and methodological obstacles

Autor: Alexandra Lebedeva, Yulia Shaykhutdinova, Daria Seriak, Ekaterina Ignatova, Ekaterina Rozhavskaya, Divyasphoorthi Vardhan, Sofia Manicka, Margarita Sharova, Tatiana Grigoreva, Ancha Baranova, Vladislav Mileyko, Maxim Ivanov

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)

Abstract Background A fraction of patients referred for complex molecular profiling of biopsied tumors may harbor germline variants in genes associated with the development of hereditary cancer syndromes (HCS). Neither the bioinformatic analysis nor

Externí odkaz: https://doaj.org/article/9b680c109ac444c3a3dd89445ab64863

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Akademický článek

The Use of Repeated Forced Social Defeat as an Animal Stress Model

Autor: Sofia Manicka, Fan Zhang, Elif Celik, Jackson Lane, Elizabeth Pottanat, Madeline Van Fossen

Publikováno v: Impulse: The Premier Undergraduate Neuroscience Journal (2022)

Over 50% of patients are resistant to current treatments for depression. With a lifetime prevalence of 20.6% among US adults, it is evident that the present understanding of major depressive disorder is limited, and current experimental methods are i

Externí odkaz: https://doaj.org/article/80a6d889f2cc43d890ffaa293bfc67c7

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Incidental germline findings during molecular profiling of tumor tissues for precision oncology: molecular survey and methodological obstacles

Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)

Background A fraction of patients referred for complex molecular profiling of biopsied tumors may harbor germline variants in genes associated with the development of hereditary cancer syndromes (HCS). Neither the bioinformatic analysis nor the repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2596f68beb67a381a9c30ee9c5edb3
https://pubmed.ncbi.nlm.nih.gov/35033101

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Effects of subanesthetic ketamine and (2R,6R) hydroxynorketamine on working memory and synaptic transmission in the nucleus reuniens in mice

Autor: Priyodarshan Goswamee, Remington Rice, Elizabeth Leggett, Fan Zhang, Sofia Manicka, Joseph H. Porter, A. Rory McQuiston

Publikováno v: Neuropharmacology

Acute cognitive impairment and abuse potential of ketamine incentivizes the search for alternatives to ketamine for clinical management of treatment-resistant depression. Recently, (2R,6R) hydroxynorketamine ((2R,6R)-HNK), a metabolite of ketamine, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69c2a0d462a3d898442edf60b95634b
https://doi.org/10.1016/j.neuropharm.2022.108965

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