Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sofia Karlstrom"'
Autor:
Sofia Karlstrom, Hongtao Zhao, Kevin E. B. Parkes, Ralf Paul, Mikaela Rapp, Dean Derbyshire, Kerstin Böhm, Mari Kullman-Magnusson, Olof Engström, Oscar Belda, Ian R. Henderson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127471
Ubiquitin specific protease-7 (USP7) is considered an attractive target for cancer therapy by promoting degradation of the tumor suppressor p53 and negatively affecting the immune response to tumors. However, the development of selective non-covalent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60af20452db2d6af002b3dc1d649279a
https://doi.org/10.1016/j.bmcl.2020.127471
https://doi.org/10.1016/j.bmcl.2020.127471
Autor:
Anders Kallin, Ian R. Henderson, Mark Albertella, Jimmy Lindberg, Sofia Karlstrom, Fredrik Öberg, Richard Bethell, Ellen Hewitt, Anna-Karin Sohlenius-Sternbeck, Susanne Sedig
Publikováno v:
Cancer Research. 76:3011-3011
Background: The aim of this study was to develop potent, selective and cell-permeable inhibitors of MALT1 protease activity. MALT1 is an Arg-specific protease that cleaves multiple substrates, acting as a key component in T- and B-cell receptor signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23bcbc23aaa245b5f24e6359c8d854c
https://doi.org/10.1158/1538-7445.am2016-3011
https://doi.org/10.1158/1538-7445.am2016-3011