Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sofia Hirth"'
Autor:
Sofia Hirth, Anja Bühler, John B Bührdel, Steven Rudeck, Tillman Dahme, Wolfgang Rottbauer, Steffen Just
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150323 (2016)
An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads to heart failure. We recently showed that Integrin-linked Kinase (ILK), ß-Parvin and PINCH
Externí odkaz:
https://doaj.org/article/fc0daef009444558a7e90b16b35ed1ab
Autor:
David C Zebrowski, Silvia Vergarajauregui, Chi-Chung Wu, Tanja Piatkowski, Robert Becker, Marina Leone, Sofia Hirth, Filomena Ricciardi, Nathalie Falk, Andreas Giessl, Steffen Just, Thomas Braun, Gilbert Weidinger, Felix B Engel
Publikováno v:
eLife, Vol 4 (2015)
Mammalian cardiomyocytes become post-mitotic shortly after birth. Understanding how this occurs is highly relevant to cardiac regenerative therapy. Yet, how cardiomyocytes achieve and maintain a post-mitotic state is unknown. Here, we show that cardi
Externí odkaz:
https://doaj.org/article/73a4b7d81d6f4b3db404f9f302d8a689
Autor:
Dieter O. Fürst, Linda Manta, Joachim Schessl, Rolf Schröder, Peter F.M. van der Ven, Benedikt Schoser, Ludwig Eichinger, Sofia Hirth, Steffen Just, Mirjam Keßler, Sören Westphal, John B. Bührdel, Christoph S. Clemen, Monika Forster, Gerhard Wiche, Wolfgang Rottbauer
Publikováno v:
Biochemical and Biophysical Research Communications. 461(2):217-223
Myofibrillar myopathies (MFM) are progressive diseases of human heart and skeletal muscle with a severe impact on life quality and expectancy of affected patients. Although recently several disease genes for myofibrillar myopathies could be identifie
Publikováno v:
Biochemical and biophysical research communications. 477(4)
In search for novel key regulators of cardiac valve formation, we isolated the zebrafish cardiac valve mutant ping pong (png). We find that an insertional promoter mutation within the zebrafish mediator complex subunit 10 (med10) gene is leading to i
Publikováno v:
Current directions in biomedical engineering, 2 (1), 233-236
Current Directions in Biomedical Engineering, Vol 2, Iss 1, Pp 233-236 (2016)
Current Directions in Biomedical Engineering, Vol 2, Iss 1, Pp 233-236 (2016)
Quantifying cardiac functions in model organisms like embryonic zebrafish is of high importance in small molecule screens for new therapeutic compounds. One relevant cardiac parameter is the fractional shortening (FS). A method for semi-automatic qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d710a741f3459a92e7c38fc2836ad59
https://publikationen.bibliothek.kit.edu/1000060219
https://publikationen.bibliothek.kit.edu/1000060219
Autor:
Silvia Vergarajauregui, David C. Zebrowski, Andreas Giessl, Marina Leone, Nathalie Falk, Felix B. Engel, Gilbert Weidinger, Tanja Piatkowski, Sofia Hirth, Steffen Just, Thomas Braun, Filomena Ricciardi, Chi-Chung Wu, Robert Becker
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
Mammalian cardiomyocytes become post-mitotic shortly after birth. Understanding how this occurs is highly relevant to cardiac regenerative therapy. Yet, how cardiomyocytes achieve and maintain a post-mitotic state is unknown. Here, we show that cardi
Autor:
Thomas Braun, Andreas Giessl, Sofia Hirth, Robert Becker, Filomena Ricciardi, Marina Leone, Steffen Just, Gilbert Weidinger, Felix B. Engel, Chi-Chung Wu, David C. Zebrowski, Tanja Piatkowski, Nathalie Falk, Silvia Vergarajauregui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b32cabefecc2082a901dd3cc90a017
https://doi.org/10.7554/elife.05563.014
https://doi.org/10.7554/elife.05563.014
Autor:
Markus Reischl, Steffen Just, R. Alshut, Wolfgang Rottbauer, Ralf Mikut, Christian Pylatiuk, Sofia Hirth, Daniela Sanchez
Publikováno v:
Zebrafish. 11(4)
A fully automatic detection and analysis method of heartbeats in videos of nonfixed and nonanesthetized zebrafish embryos is presented. This method reduces the manual workload and time needed for preparation and imaging of the zebrafish embryos, as w
Autor:
Meike Hermann, Sofia Hirth, Artur J. P. Pfitzner, Ursula M. Pfitzner, Ashir Masroor, Felix Maier
Publikováno v:
Frontiers in Plant Science
Frontiers in Plant Science, Vol 4 (2013)
Frontiers in Plant Science, Vol 4 (2013)
NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) is the central regulator of the pathogen defense reaction systemic acquired resistance (SAR). NPR1 acts by sensing the SAR signal molecule salicylic acid (SA) to induce expression of PATHOGENESIS-RE