Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sofia Halin Bergström"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Advanced cancers induce systemic responses. However, if such systemic changes occur already when aggressive tumors are small, have not been thoroughly characterized. Here, we examined how localized prostate cancers of different sizes and met
Externí odkaz:
https://doaj.org/article/79ac42b6a291460fa3cc8feee8b90c15
Autor:
Helena Järemo, Julius Semenas, Sofia Halin Bergström, Marie Lundholm, Elin Thysell, Anders Widmark, Sead Crnalic, Erik Bovinder Ylitalo, Anders Bergh, Maria Brattsand, Pernilla Wikström
Publikováno v:
Cancers, Vol 15, Iss 9, p 2437 (2023)
MicroRNAs (miRNAs) are aberrantly expressed in prostate cancer (PC), but comprehensive knowledge about their levels and function in metastatic PC is lacking. Here, we explored the differential expression of miRNA profiles during PC progression to bon
Externí odkaz:
https://doaj.org/article/5b71d4befa3b4001a2c54c67f306993b
Autor:
Pernilla Wikström, Sofia Halin Bergström, Andreas Josefsson, Julius Semenas, Annika Nordstrand, Elin Thysell, Sead Crnalic, Anders Widmark, Camilla Thellenberg Karlsson, Anders Bergh
Publikováno v:
Cancers, Vol 14, Iss 21, p 5195 (2022)
Prostate cancer (PC) bone metastases can be divided into transcriptomic subtypes, by us termed MetA-C. The MetB subtype, constituting about 20% of the cases, is characterized by high cell cycle activity, low androgen receptor (AR) activity, and a lim
Externí odkaz:
https://doaj.org/article/57313bd012bd4bec967c15338bdb3f2f
Autor:
Anna-Maja Åberg, Sofia Halin Bergström, Elin Thysell, Lee-Ann Tjon-Kon-Fat, Jonas A. Nilsson, Anders Widmark, Camilla Thellenberg-Karlsson, Anders Bergh, Pernilla Wikström, Marie Lundholm
Publikováno v:
Cancers, Vol 13, Iss 10, p 2424 (2021)
Increasing evidence indicates calcium-binding S100 protein involvement in inflammation and tumor progression. In this prospective study, we evaluated the mRNA levels of two members of this family, S100A9 and S100A12, in peripheral blood mononuclear c
Externí odkaz:
https://doaj.org/article/79a7a621b2ef476caf1085a9087c2160
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 3, Pp 152-161 (2016)
Prostate cancer generally metastasizes to bone, and most patients have tumor cells in their bone marrow already at diagnosis. Tumor cells at the metastatic site may therefore progress in parallel with those in the primary tumor. Androgen deprivation
Externí odkaz:
https://doaj.org/article/3bd16f18bd1f4142b6448d68156c4edd
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176679 (2017)
In order to grow and spread tumors need to interact with adjacent tissues. We therefore hypothesized that small but aggressive prostate cancers influence the rest of the prostate and regional lymph nodes differently than tumors that are more indolent
Externí odkaz:
https://doaj.org/article/fa2e0c0f06254cee810bb4d8ecfcc00d
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0187086 (2017)
The aim of this study was to examine in what ways MatLyLu (MLL) rat prostate tumors with high metastatic capacity influence regional lymph nodes prior to metastatic establishment compared to AT1 rat prostate tumors with low metastatic potential. MLL
Externí odkaz:
https://doaj.org/article/8fefeee12a8c468ba1ccad1fb2e50646
Autor:
Sofia Halin Bergström, Maria Nilsson, Hanibal Adamo, Elin Thysell, Emma Jernberg, Pär Stattin, Anders Widmark, Pernilla Wikström, Anders Bergh
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157280 (2016)
Aggressive tumors induce tumor-supporting changes in the benign parts of the prostate. One factor that has increased expression outside prostate tumors is hemoxygenase-1 (HO-1). To investigate HO-1 expression in more detail, we analyzed samples of tu
Externí odkaz:
https://doaj.org/article/90173ad0d3a74cb2b636aa09993af10c
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130076 (2015)
Implantation of rat prostate cancer cells into the normal rat prostate results in tumor-stimulating changes in the tumor-bearing organ, for example growth of the vasculature, an altered extracellular matrix, and influx of inflammatory cells. To inves
Externí odkaz:
https://doaj.org/article/6df917cddc0b45c8bfaf875e98287c10
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141601 (2015)
In order to grow, tumors need to induce supportive alterations in the tumor-bearing organ, by us named tumor instructed normal tissue (TINT) changes. We now examined if the nature and magnitude of these responses were related to tumor size and aggres
Externí odkaz:
https://doaj.org/article/e734f0b27c8e418087fcb144f8eb7e53