Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sofia Gkountela"'
Autor:
Ellen Weisberg, Basudev Chowdhury, Chengcheng Meng, Abigail E. Case, Wei Ni, Swati Garg, Martin Sattler, Abdel Kareem Azab, Jennifer Sun, Barbara Muz, Dana Sanchez, Anthia Toure, Richard M. Stone, Ilene Galinsky, Eric Winer, Scott Gleim, Sofia Gkountela, Alexia Kedves, Edmund Harrington, Tinya Abrams, Thomas Zoller, Andrea Vaupel, Paul Manley, Michael Faller, BoYee Chung, Xin Chen, Philipp Busenhart, Christine Stephan, Keith Calkins, Debora Bonenfant, Claudio R. Thoma, William Forrester, James D. Griffin
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 7, Pp 1-10 (2022)
Abstract Bromodomain-containing protein 9 (BRD9), an essential component of the SWI/SNF chromatin remodeling complex termed ncBAF, has been established as a therapeutic target in a subset of sarcomas and leukemias. Here, we used novel small molecule
Externí odkaz:
https://doaj.org/article/3c275c0fed054a4ca5adaa6cd08da2ce
Autor:
Marcus Vetter, Julia Landin, Barbara Maria Szczerba, Francesc Castro-Giner, Sofia Gkountela, Cinzia Donato, Ilona Krol, Ramona Scherrer, Catharina Balmelli, Alexandra Malinovska, Alfred Zippelius, Christian Kurzeder, Viola Heinzelmann-Schwarz, Walter Paul Weber, Christoph Rochlitz, Nicola Aceto
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background The presence of circulating tumor cells (CTCs) in patients with breast cancer correlates to a bad prognosis. Yet, CTCs are detectable in only a minority of patients with progressive breast cancer, and factors that influence the ab
Externí odkaz:
https://doaj.org/article/43f7382f038c4900b8a3ff9d6985a08e
Autor:
Amander T. Clark, Sofia Gkountela, Di Chen, Wanlu Liu, Enrique Sosa, Meena Sukhwani, Jon D. Hennebold, Kyle E. Orwig
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 329-341 (2017)
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult. Recent work has shown that primate PGCs can be differentiated from pluripotent stem cells;
Externí odkaz:
https://doaj.org/article/29b3d5f8be1f4c62b0e028d2028f209c
Autor:
Francesc Castro-Giner, Sofia Gkountela, Cinzia Donato, Ilaria Alborelli, Luca Quagliata, Charlotte K. Y. Ng, Salvatore Piscuoglio, Nicola Aceto
Publikováno v:
Diagnostics, Vol 8, Iss 2, p 31 (2018)
The field of cancer diagnostics has recently been impacted by new and exciting developments in the area of liquid biopsy. A liquid biopsy is a minimally invasive alternative to surgical biopsies of solid tissues, typically achieved through the withdr
Externí odkaz:
https://doaj.org/article/8a36a35c285f403d882e8a3332ee1fcf
Autor:
Sofia Gkountela, Amander Clark
Publikováno v:
Bio-Protocol, Vol 3, Iss 12 (2013)
High throughput RNA Sequencing has revolutionized transcriptome analyses. However, most available protocols require micrograms of RNA rendering this technique not feasible for analyzing small numbers of cells, including precious rare cell types isola
Externí odkaz:
https://doaj.org/article/1b7c9d3901b146609038b1b9d72d7f74
Autor:
John J Vincent, Ziwei Li, Serena A Lee, Xian Liu, Marisabel O Etter, Silvia V Diaz-Perez, Sara K Taylor, Sofia Gkountela, Anne G Lindgren, Amander T Clark
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28960 (2011)
The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse
Externí odkaz:
https://doaj.org/article/41385781e12541d0a8635b498f0d0413
Autor:
Nicola Aceto, Randall J. Platt, Timm Schroeder, Claudio Giachino, Verdon Taylor, Christoph Rochlitz, Marcus Vetter, Leo Kunz, Tatjana Vlajnic, Simone Muenst, Zoi Diamantopoulou, Barbara M. Szczerba, Sofia Gkountela, Cinzia Donato, Ramona Scherrer, Aino Paasinen-Sohns, Ilona Krol, Karin Strittmatter, Francesc Castro-Giner, Manuel C. Scheidmann
Blood-borne metastasis of breast cancer involves a series of tightly regulated sequential steps, including the growth of a primary tumor lesion, intravasation of circulating tumor cells (CTC), and adaptation in various distant metastatic sites. The g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d089ec90c9d9d5016ec75589de1da40
https://doi.org/10.1158/0008-5472.c.6513747.v1
https://doi.org/10.1158/0008-5472.c.6513747.v1
Autor:
Nicola Aceto, Randall J. Platt, Timm Schroeder, Claudio Giachino, Verdon Taylor, Christoph Rochlitz, Marcus Vetter, Leo Kunz, Tatjana Vlajnic, Simone Muenst, Zoi Diamantopoulou, Barbara M. Szczerba, Sofia Gkountela, Cinzia Donato, Ramona Scherrer, Aino Paasinen-Sohns, Ilona Krol, Karin Strittmatter, Francesc Castro-Giner, Manuel C. Scheidmann
Supplementary Table from An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ec14b7ae2331fab6c94f7e0174a5bd
https://doi.org/10.1158/0008-5472.22430934.v1
https://doi.org/10.1158/0008-5472.22430934.v1
Autor:
Nicola Aceto, Randall J. Platt, Timm Schroeder, Claudio Giachino, Verdon Taylor, Christoph Rochlitz, Marcus Vetter, Leo Kunz, Tatjana Vlajnic, Simone Muenst, Zoi Diamantopoulou, Barbara M. Szczerba, Sofia Gkountela, Cinzia Donato, Ramona Scherrer, Aino Paasinen-Sohns, Ilona Krol, Karin Strittmatter, Francesc Castro-Giner, Manuel C. Scheidmann
Supplementary Figure from An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176b311f7743882a50f8ba2d1821d135
https://doi.org/10.1158/0008-5472.22430952.v1
https://doi.org/10.1158/0008-5472.22430952.v1
Autor:
Manuel C. Scheidmann, Francesc Castro-Giner, Karin Strittmatter, Ilona Krol, Aino Paasinen-Sohns, Ramona Scherrer, Cinzia Donato, Sofia Gkountela, Barbara M. Szczerba, Zoi Diamantopoulou, Simone Muenst, Tatjana Vlajnic, Leo Kunz, Marcus Vetter, Christoph Rochlitz, Verdon Taylor, Claudio Giachino, Timm Schroeder, Randall J. Platt, Nicola Aceto
Publikováno v:
Cancer Res
Cancer Research, 82 (4)
Cancer Research, 82 (4)
Blood-borne metastasis of breast cancer involves a series of tightly regulated sequential steps, including the growth of a primary tumor lesion, intravasation of circulating tumor cells (CTC), and adaptation in various distant metastatic sites. The g