Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sofia Gargani"'
Autor:
Ourania Galanopoulou, Evangelia C. Tachmatzidi, Elena Deligianni, Dimitris Botskaris, Kostas C. Nikolaou, Sofia Gargani, Yannis Dalezios, Georges Chalepakis, Iannis Talianidis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Setd8 regulates transcription elongation, mitotic DNA condensation, DNA damage response and replication licensing. Here we show that, in mitogen-stimulated liver-specific Setd8-KO mice, most of the hepatocytes are eliminated by necrosis but
Externí odkaz:
https://doaj.org/article/7a63db086b584fafb014bb779aded084
Autor:
Stella Aikaterini Kyriakoudi, Despoina Chatzi, Iasonas Dermitzakis, Sofia Gargani, Maria Eleni Manthou, Soultana Meditskou, Paschalis Theotokis
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 261 (2024)
The neural crest (NC), also known as the “fourth germ layer”, is an embryonic structure with important contributions to multiple tissue and organ systems. Neural crest cells (NCCs) are subjected to epithelial to mesenchymal transition and migrate
Externí odkaz:
https://doaj.org/article/e723d32d8ac74fbe9445c5183e261acc
Autor:
Sofia Gargani, Niki Lourou, Christina Arapatzi, Dimitris Tzanos, Marania Saridaki, Esmeralda Dushku, Margarita Chatzimike, Nikolaos D. Sidiropoulos, Margarita Andreadou, Vasileios Ntafis, Pantelis Hatzis, Vassiliki Kostourou, Dimitris L. Kontoyiannis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The four isoforms of the RNA-binding protein hnRNPD/AUF1 have been proposed to limit the use of inflammatory mRNAs in innate immune cells. Mice engineered to lack AUF1s in all tissues are sensitive to acute inflammatory assaults; however, they also m
Externí odkaz:
https://doaj.org/article/c2ef2a1e13b4410ca0af30517f818666
Autor:
Rémy Bonnavion, Rami Jaafar, Julie Kerr-Conte, Fouzia Assade, Esther van Stralen, Emmanuelle Leteurtre, Célio Pouponnot, Sofia Gargani, François Pattou, Philippe Bertolino, Martine Cordier-Bussat, Jieli Lu, Chang Xian Zhang
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72194 (2013)
Pax4 and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene homolog A) are two transcription factors crucial for normal functions of islet beta cells in the mouse. Intriguingly, recent studies indicate the existence of notable difference between hu
Externí odkaz:
https://doaj.org/article/0be19846c33a4159930cbefa9ae61f41
Autor:
Nicola Zamboni, Andreas Petzold, Anke Witt, Margarita Andreadou, Peter Mirtschink, Vasileios Ntafis, Ünal Coskun, Anastasios D Papanastasiou, Veera Raghavan Thangapandi, Robert Haase, Ioannis Kourtzelis, Triantafyllos Chavakis, Iryna Pyrina, Kyoung-Jin Chung, Ralph Burkhardt, Mirko Peitzsch, Bettina Gercken, Sofia Gargani, Pallavi Subramanian, Margarita Chatzimike, Dimitris L. Kontoyiannis, Ian Henry, Marina Nati, Michal Grzybek, Jochen Hampe, Anupam Sinha, Alessandra Palladini, Andreas Dahl, António Miguel de Jesus Domingues, Mathias Lesche
Publikováno v:
Hepatology
Hepatology, 75 (4)
Hepatology, 75 (4)
BACKGROUND AND AIMS: NAFLD is initiated by steatosis and can progress through fibrosis and cirrhosis to HCC. The RNA binding protein human antigen R (HuR) controls RNAs at the posttranscriptional level; hepatocyte HuR has been implicated in the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38253cb373e906bced2d258b9956387b
Autor:
Emad A. Rakha, Angeliki Ditsiou, Graeme Benstead-Hume, Michael Dean, Viviana Vella, Timothy O’Hanlon, Leping Li, Kritika Yadav, Erwei Song, Kamila Bienkowska, Andrew R. Green, Justin Stebbing, Philip Carter, Vasileios Ntafis, Dimitris L. Kontoyiannis, Jianing Chen, Kalpit Shah, Mansour Alsaleem, Frances M. G. Pearl, Sofia Gargani, Kai Kang, Teresa Gagliano, Soo-Chin Lee, Liyan Lao, Georgios Giamas, Giulia Bresciani, Penghan Huang
Publikováno v:
J Clin Invest
As there is growing evidence for the tumor microenvironment’s role in tumorigenesis, we investigated the role of fibroblast-expressed kinases in triple-negative breast cancer (TNBC). Using a high-throughput kinome screen combined with 3D invasion a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854b668c071cb69c90322dea6403cb6c
Autor:
Julien Thevenet, Clara Clabaut, François Pattou, Caroline Bonner, Pauline Petit, Sofia Gargani, Julie Kerr-Conte, Valery Gmyr, Gianni Pasquetti
Publikováno v:
Diabetes. 69
A translational discrepancy exists between animal models used for diabetes research and diabetes in man, thus human relevant models must become a priority. We showed that collectively human islet grafts from 26 donors statistically significantly adap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08e5686481b672e9c888d00e254c3310
https://doi.org/10.2337/db20-2056-p
https://doi.org/10.2337/db20-2056-p
Autor:
Kalpit Shah, Timothy O’Hanlon, Viviana Vella, Dimitris L. Kontoyiannis, Michael Dean, Angeliki Ditsiou, Soo-Chin Lee, Georgios Giamas, Kai Kang, Graeme Benstead-Hum, Emad A. Rakha, Teresa Gagliano, Jianing Chen, Penghan Huang, Leping Li, Kritika Yadav, Erwei Song, Sofia Gargani, Kamila Bienkowska, Liyan Lao, Andrew R. Green, Giulia Bresciani, Philip Carter, Mansour Alsaleem, Frances M. G. Pearl, Justin Stebbing, Vasileios Ntafis
As there is growing evidence for the tumor microenvironment’s (TME) role in tumorigenesis, we sought to investigate the role of fibroblast-expressed kinases in triple negative breast cancer (TNBC). Using a high-throughput kinome screen combined wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eaf1cd4bed408e7dc79fd3f613e53be
Autor:
François Pattou, Bernadette Neve, Marlène Huyvaert, O Le Bacquer, N. Delalleau, Sofia Gargani, Julie Kerr-Conte, Valery Gmyr, Philippe Froguel
Publikováno v:
Diabetologia. 55:2677-2681
Aims/hypothesis Transcription factor 7-like 2 (TCF7L2) is a Wnt-signalling-associated transcription factor. Genetic studies have clearly demonstrated that DNA polymorphisms within TCF7L2 confer the strongest known association with increased risk of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb4007b924d730c431bda4063681a8c
https://doi.org/10.1007/s00125-012-2660-8
https://doi.org/10.1007/s00125-012-2660-8
Autor:
Sofia Gargani, Anastasia Petsa, Karina-Alina Ardelean, Iliana Karvounidou, Vassilios Katsares, Nikolaos Grigoriadis, Zissis Paparidis, John Grigoriadis, Eleni Nikolaidou, Antigonos Felesakis
Publikováno v:
Laboratory Medicine. 40:557-560
The umbilical cord blood (UCB) is a major source of hematopoietic progenitor cells. These cells can be cryopreserved for possible future use. In order to evaluate the viability of cryopreserved progenitor cells, a small amount of cells is thawed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7eee464431183f7c294fec0c28eff37
https://doi.org/10.1309/lmle8bvhywct82cl
https://doi.org/10.1309/lmle8bvhywct82cl