Sublingual protein delivery by a mucoadhesive patch made of natural polymers

Autor: Claire Monge, Eléa Boucard, Anne-Lise Paris, Evelyne Colomb, Bernard Verrier, Mélanie Bellina, Sofia G. Caridade

Publikováno v: Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2021, 128, pp.222-235. ⟨10.1016/j.actbio.2021.04.024⟩

The sublingual mucosa is an appealing route for drug administration. However, in the context of increased use of therapeutic proteins, development of protein delivery systems that will protect the protein bioactivity is needed. As proteins are fragil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a8d9fd3d6aa633dceff72fd0058056
https://hal.archives-ouvertes.fr/hal-03434581

Injectable Hyaluronic Acid Hydrogels Enriched with Platelet Lysate as a Cryostable Off-the-Shelf System for Cell-Based Therapies

Autor: Sofia G. Caridade, Ana I. Gonçalves, Lisete S. Neves, Manuela E. Gomes, Rui M. A. Domingues, Pedro S. Babo, Márcia T. Rodrigues, Raquel Costa Almeida, João F. Mano, Rui L. Reis

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Cell-based regenerative medicine strategies hold a great potential to revolutionize the treatment of a large number of injuries with limited regenerative potential. However, the effectiveness of the simple injection of a cell suspension in a target s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230c8eae30426b02db4a7c6fe3c868bd
https://doi.org/10.1007/s40883-017-0029-8

Biomineralization in chitosan/Bioglass® composite membranes under different dynamic mechanical conditions

Autor: Natália M. Alves, Sofia G. Caridade, João F. Mano, Esther G. Merino

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Fundamental aspects of biomineralization may be important in order to understand and improve calcification onto the surface of biomaterials. The biomineralization process is mainly followed in vitro by assessing the evolution of the apatite layer tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85787ee2cc269382f82155b9733a10c0
https://doi.org/10.1016/j.msec.2013.06.044

High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers

Autor: Eunice Cunha, Natália M. Alves, João F. Mano, Duarte Moura, Sofia G. Caridade, Maria C. Paiva, Helena Rocha, Maria P. Sousa

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Moura, D, Caridade, S G, Sousa, M P, Cunha, E, Rocha, H C, Mano, J F, Da Conceição Paiva, M & Alves, N M 2016, ' High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers ', Journal of Materials Chemistry B, vol. 4, no. 47, pp. 7718-7730 . https://doi.org/10.1039/c6tb02344d

In this work, novel free-standing (FS) films based on chitosan, alginate and graphene oxide (GO) were developed through layer-by-layer assembly. First, GO was synthesized from graphite and multi-walled carbon nanotubes using a modified Hummer's metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12514fc7037db87d7ed8b88558e9731
https://hdl.handle.net/1822/43832

Cell Alignment: Control of Cell Alignment and Morphology by Redesigning ECM-Mimetic Nanotopography on Multilayer Membranes (Adv. Healthcare Mater. 15/2017)

Autor: João F. Mano, Sofia G. Caridade, Maria P. Sousa

Publikováno v: Advanced Healthcare Materials. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::456fd700403d8958f0841847c95c00bb
https://doi.org/10.1002/adhm.201770079