Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sofia Duque Santos"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Platinum nanoparticles (PtNPs) have unique physico-chemical properties that led to their use in many branches of medicine. Recently, PtNPs gathered growing interest as delivery vectors for drugs, biosensors and as surface coating on chronically impla
Externí odkaz:
https://doaj.org/article/61acf39b45664d1aa543304da23f9262
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The development of implantable neuroelectrodes is advancing rapidly as these tools are becoming increasingly ubiquitous in clinical practice, especially for the treatment of traumatic and neurodegenerative disorders. Electrodes have been exploited in
Externí odkaz:
https://doaj.org/article/4d8635b1a4c24f6f8e5054fef1c12cc6
Autor:
Alexandra Isabel Rosa, Sofia Grade, Sofia Duque Santos, Liliana Bernardino, Thomas C Chen, João Relvas, Florence M Hofman, Fabienne Agasse
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Neurogenesis in the subventricular zone (SVZ) is regulated by diffusible factors and cell-cell contacts. In vivo, SVZ stem cells are associated with the abluminal surface of blood vessels and such interactions are thought to regulate their neurogenic
Externí odkaz:
https://doaj.org/article/b1048b209ec0442d89ddd13aa67fdd81
Autor:
Victoria Leiro, Sara C. Silva-Reis, Ana Paula Pêgo, Marília Torrado, Beatriz Custódio, Sofia Duque Santos, Ana Patrícia Spencer
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 2, p 192 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Pharmaceutics, Vol 12, Iss 2, p 192 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Central nervous system (CNS) disorders encompass a vast spectrum of pathological conditions and represent a growing concern worldwide. Despite the high social and clinical interest in trying to solve these pathologies, there are many challenges to br
Autor:
Rui Loja Fernandes, Sofia Duque Santos, Renato Socodato, Cord Brakebusch, Kate Lykke Lambertsen, Francisco Figueiredo, Cansu Karabiyik, João B. Relvas
Publikováno v:
Brain Pathology. 28:569-580
The Rho GTPase Rac1 is a multifunctional protein involved in distinct pathways ranging from development to pathology. The aim of the present study was to unravel the contribution of neuronal Rac1 in regulating the response to brain injury induced by
Autor:
Sofia Duque Santos, Miguel Xavier, Helena Tomás, Marília Torrado, Rita Castro, João Rodrigues, Ana Paula Pêgo, Victoria Leiro, Beatriz Custódio, Débora A. Moreira, Diana Moreira Leite
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Drug delivery to the central nervous system is restricted by the blood-brain barrier (BBB). However, with the onset of stroke, the BBB becomes leaky, providing a window of opportunity to passively target the brain. Here, cationic poly(amido amine) (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffc51ae1a53490a51f6137c7a8027de
Autor:
João B. Relvas, Maria João Saraiva, J P Ferraz-Nogueira, Marta Vieira, Sofia Duque Santos, João R. Gomes, Renata Nogueira
Publikováno v:
Cell Death and Differentiation
Transthyretin (TTR) is a protein whose function has been associated to binding and distribution of thyroid hormones in the body and brain. However, little is known regarding the downstream signaling pathways triggered by wild-type TTR in the CNS eith
Autor:
Pedro Martins, Sofia Duque Santos, Alexandra R. Fernandes, João Jesus, Luís Raposo, Pedro V. Baptista, Catarina Roma-Rodrigues
Publikováno v:
Molecules
Molecules, Vol 20, Iss 9, Pp 16852-16891 (2015)
Molecules, Vol 20, Iss 9, Pp 16852-16891 (2015)
The majority of heterocycle compounds and typically common heterocycle fragments present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility and unique physicochemical properties, have poised them as true cornerston
Publikováno v:
IET Nanobiotechnology. 9:95-101
The optical and physico-chemical properties of gold nanoparticles (AuNPs) have prompted new and improved approaches which have greatly evolved the fields of biosensing and molecular detection. In this study, the authors took advantage of AuNPs' ease
Autor:
Marta S. Rafael, Brecht A. G. Willems, José L. Enriquez, José Neves, Inês M. Luís, Sofia Cavaco, Anjos L. Macedo, Ruben Martins Da Costa, Cees Vermeer, Dina C. Simes, Rui Vitorino, Carla Viegas, Sofia Duque Santos, Alexandra Teixeira
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 35(2), 399-408. LIPPINCOTT WILLIAMS & WILKINS
Objective— Vascular and valvular calcifications are pathological processes regulated by resident cells, and depending on a complex interplay between calcification promoters and inhibitors, resembling skeletal metabolism. Here, we study the role of