Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sofia Cussotto"'
Autor:
Sofia Cussotto, Jacinta Walsh, Anna V. Golubeva, Alexander V. Zhdanov, Conall R. Strain, Fiona Fouhy, Catherine Stanton, Timothy G. Dinan, Niall P. Hyland, Gerard Clarke, John F. Cryan, Brendan T. Griffin
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103307- (2021)
Background: The role of the gut microbiome in the biotransformation of drugs has recently come under scrutiny. It remains unclear whether the gut microbiome directly influences the extent of drug absorbed after oral administration and thus potentiall
Externí odkaz:
https://doaj.org/article/90a73ebf29cd4ea7aae7e7a551725c50
Autor:
Sofia Cussotto, Inês Delgado, Andrea Anesi, Sandra Dexpert, Agnès Aubert, Cédric Beau, Damien Forestier, Patrick Ledaguenel, Eric Magne, Fulvio Mattivi, Lucile Capuron
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: Obesity is a condition with a complex pathophysiology characterized by both chronic low-grade inflammation and changes in the gut microbial ecosystem. These alterations can affect the metabolism of tryptophan (TRP), an essential amino aci
Externí odkaz:
https://doaj.org/article/15b370f71ad34b49b4ff014bd57364a6
Autor:
Sofia Cussotto, Inês Delgado, Giovanni Oriolo, Jonas Kemper, Diane Begarie, Sandra Dexpert, Julie Sauvant, Marion Leboyer, Bruno Aouizerate, Rocío Martin‐Santos, Martin Schaefer, Lucile Capuron
Publikováno v:
Depression and anxietyREFERENCES. 39(5)
Major depressive disorder (MDD) is characterized by a high rate of treatment resistance. Omega (ω)-3 polyunsaturated fatty acids (PUFAs) were shown to correlate with depressive phenotype both in rodents and in humans. However, few studies to date ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d9188a28340e9fdb1a722389f6bb25
https://pubmed.ncbi.nlm.nih.gov/35357051
https://pubmed.ncbi.nlm.nih.gov/35357051
Publikováno v:
Psychopharmacology
The human gut contains trillions of symbiotic bacteria that play a key role in programming different aspects of host physiology in health and disease. Psychotropic medications act on the central nervous system (CNS) and are used in the treatment of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d02bb5e532cf46528ae59c59cb890b
http://europepmc.org/articles/PMC6598948
http://europepmc.org/articles/PMC6598948
Autor:
Inês Delgado, Sofia Cussotto, Andrea Anesi, Sandra Dexpert, Agnès Aubert, Bruno Aouizerate, Cédric Beau, Damien Forestier, Patrick Ledaguenel, Eric Magne, Fulvio Mattivi, Lucile Capuron
Publikováno v:
International journal of obesity (2005). 46(4)
Converging data support the role of chronic low-grade inflammation in depressive symptomatology in obesity. One mechanism likely to be involved relies on the effects of inflammation on tryptophan (TRP) metabolism. While recent data document alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2763430a6fc5b58cd67f21d1251a1b78
https://pubmed.ncbi.nlm.nih.gov/35001078
https://pubmed.ncbi.nlm.nih.gov/35001078
Publikováno v:
Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, Elsevier, 2021, 94, pp.4-5. ⟨10.1016/j.bbi.2021.02.029⟩
Brain, Behavior, and Immunity, Elsevier, 2021, 94, pp.4-5. ⟨10.1016/j.bbi.2021.02.029⟩
Emerging evidence indicates that disruption of the gut microbial community (dysbiosis) impairs mental health. Germ-free mice and antibiotic-induced gut dysbiosis are two approaches to establish causality in gut microbiota-brain relationships. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb26e3bfaf02f38963ddf2f7d391a25
https://pubmed.ncbi.nlm.nih.gov/26923630
https://pubmed.ncbi.nlm.nih.gov/26923630
The human gut microbiome plays a key role in host physiology in health and disease. There is a growing emphasis on the bidirectional interaction between various medications and the gut microbiome. Here, we will first review how drugs can affect micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f282e80872af917cdf664e093c20074c
https://doi.org/10.1159/000510423
https://doi.org/10.1159/000510423
Publikováno v:
Modern trends in psychiatry. 32
The human gut microbiome plays a key role in host physiology in health and disease. There is a growing emphasis on the bidirectional interaction between various medications and the gut microbiome. Here, we will first review how drugs can affect micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::391679be42956db2b9fa3cbfeeb0dd01
https://pubmed.ncbi.nlm.nih.gov/34032649
https://pubmed.ncbi.nlm.nih.gov/34032649
Autor:
Timothy G. Dinan, Ronan Strain, Catherine Stanton, Fiona Fouhy, Sofia Cussotto, Gerard Clarke, Conall R. Strain, John F. Cryan, Veronica L. Peterson
Publikováno v:
Psychopharmacology. 236:1671-1685
Growing evidence supports a role for the microbiota in regulating gut-brain interactions and, thus, psychiatric disorders. Despite substantial scientific efforts to delineate the mechanism of action of psychotropic medications at a central nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d01543c012f4fdb6afae30fd9b127e
https://doi.org/10.1007/s00213-018-5006-5
https://doi.org/10.1007/s00213-018-5006-5
Publikováno v:
Neuroscience Letters. 648:14-20
Approximately 50% of depressed individuals fail to achieve remission with first-line antidepressant drugs and a third remain treatment-resistant. When first-line antidepressant treatment is unsuccessful, second-line strategies include dose optimisati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985bd9dae25680722d661213168422d7
https://doi.org/10.1016/j.neulet.2017.03.040
https://doi.org/10.1016/j.neulet.2017.03.040