Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sofia B. Winge"'
Autor:
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-9 (2024)
Abstract Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis. Here, we show that t
Externí odkaz:
https://doaj.org/article/213b1e601e994cd09253e3f58a93d4b8
Autor:
Svante Pääbo, Henrik Kaessmann, Thoomke Brüning, Frank Grützner, Philipp Khaitovich, Francesco Lamanna, Mari Sepp, Meritxell Riera Belles, Julia Schmidt, Katharina Mößinger, Christian Conrad, Rüdiger Behr, Celine Schneider, Ronald E. Bontrop, Sofia B. Winge, Kristian Almstrup, Timo Trefzer, Florent Murat, Ivanela Kondova, Margarida Cardoso-Moreira, Evgeny Leushkin, Noe Mbengue, Mikkel H. Schierup, Tomas Marques-Bonet
Publikováno v:
Murat, F, Mbengue, N, Winge, S, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Riera Belles, M, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature .
Murat, F, Mbengue, N, Winge, S B, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Belles, M R, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature, vol. 613, pp. 308–316 . https://doi.org/10.1038/s41586-022-05547-7
Nature, 613. Nature Research
Nature
Murat, F, Mbengue, N, Winge, S B, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Belles, M R, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature, vol. 613, pp. 308–316 . https://doi.org/10.1038/s41586-022-05547-7
Nature, 613. Nature Research
Nature
The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological and molecular level in mammals1-6, probably owing to the evolutionary pressure on males to be reproductively successful7. However, the molecular evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b94a7cb3b0894be247c9cbeae7eff
Autor:
Liina Nagirnaja, Kristian Almstrup, Sofia B. Winge, Donald F. Conrad, Kenneth I. Aston, Filipa Carvalho, Peter N. Schlegel, Nina Mørup, Niels E. Skakkebæk, Alexandra M. Lopes, Niels Jørgensen, C. Joana Marques, Francesca Khani, Ieva Golubickaite, John E. Nielsen, Manon S. Oud, Ewa Rajpert-De Meyts, Joris A. Veltman, Rytis Stakaitis, Godfried W. van der Heijden
Publikováno v:
The New England Journal of Medicine, 385, 707-719
Nagirnaja, L, Mørup, N, Nielsen, J E, Stakaitis, R, Golubickaite, I, Oud, M S, Winge, S B, Carvalho, F, Aston, K I, Khani, F, Van Der Heijden, G W, Marques, C J, Skakkebaek, N E, Rajpert–de Meyts, E, Schlegel, P N, Jørgensen, N, Veltman, J A, Lopes, A M, Conrad, D F & Almstrup, K 2021, ' Variant PNLDC1, Defective piRNA Processing, and Azoospermia ', New England Journal of Medicine, vol. 385, no. 8, pp. 707-719 . https://doi.org/10.1056/NEJMoa2028973
The New England Journal of Medicine, 385, 8, pp. 707-719
Nagirnaja, L, Mørup, N, Nielsen, J E, Stakaitis, R, Golubickaite, I, Oud, M S, Winge, S B, Carvalho, F, Aston, K I, Khani, F, Van Der Heijden, G W, Marques, C J, Skakkebaek, N E, Rajpert–de Meyts, E, Schlegel, P N, Jørgensen, N, Veltman, J A, Lopes, A M, Conrad, D F & Almstrup, K 2021, ' Variant PNLDC1, Defective piRNA Processing, and Azoospermia ', New England Journal of Medicine, vol. 385, no. 8, pp. 707-719 . https://doi.org/10.1056/NEJMoa2028973
The New England Journal of Medicine, 385, 8, pp. 707-719
Item does not contain fulltext BACKGROUND: P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expressio
Autor:
Kristian Almstrup, Sofia B. Winge
Publikováno v:
Human Reproduction Update. 27:967-969
Autor:
Sofia B. Winge, Bernard Jégou, Anne Jørgensen, Niels E. Skakkebæk, David Møbjerg Kristensen, John E. Nielsen, Antoine Rolland, Frédéric Chalmel, Christian Janfelt, Ewa Rajpert-De Meyts, Anders Juul
Publikováno v:
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.1267. ⟨10.1038/s41598-020-58153-w⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1267. ⟨10.1038/s41598-020-58153-w⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Scientific Reports, 2020, 10 (1), pp.1267. ⟨10.1038/s41598-020-58153-w⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1267. ⟨10.1038/s41598-020-58153-w⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167aee23f4c00f3a5947f50e85ea93a6
https://hal.ehesp.fr/hal-02464404/file/s41598-020-58153-w.pdf
https://hal.ehesp.fr/hal-02464404/file/s41598-020-58153-w.pdf
Autor:
Kristian Almstrup, Loa Nordkap, Stine A. Holmboe, Sofia B. Winge, Niels Jørgensen, Martin Blomberg Jensen, Anne Kirstine Bang, Helene Westring Hvidman, Jørgen Holm Petersen, Anders Juul, Marianna Krause, Inge A. Olesen, Ewa Rajpert-De Meyts, Dorte Louise Egeberg Palme, Ulla Nordström Joensen, Lærke Priskorn
Publikováno v:
AndrologyREFERENCES. 9(2)
Background Spermatogenesis depends on stimulation by follicle-stimulating hormone (FSH) which binds to FSH receptors (FSHR) on testicular Sertoli cells. Three FSH-related single nucleotide polymorphisms (SNPs); FSHB -211G>T (rs10835638), FSHR -29G>A
Autor:
Nina Mørup, Anne Kirstine Bang, Elvira Vaclavik Bräuner, Tina Kold Jensen, Sofia B. Winge, Niels Jørgensen, Dorte Louise Egeberg Palme, Niels E. Skakkebæk, Loa Nordkap, Stine A. Holmboe, Åse Marie Hansen, Lærke Priskorn
Publikováno v:
Nordkap, L, Priskorn, L, Bräuner, E V, Marie Hansen, Å, Kirstine Bang, A, Holmboe, S A, Winge, S B, Egeberg Palme, D L, Mørup, N, Erik Skakkebæk, N, Kold Jensen, T & Jørgensen, N 2020, ' Impact of psychological stress measured in three different scales on testis function : A cross-sectional study of 1362 young men ', Andrology, vol. 8, no. 6, pp. 1674-1686 . https://doi.org/10.1111/andr.12835
Background: Studies have reported associations between psychological stress and semen quality, but most have been performed on selected populations using different stress measures. Thus, it is uncertain which stress scale best quantifies the effects
Characterisation and localisation of the endocannabinoid system components in the adult human testis
Autor:
Anders Juul, Frédéric Chalmel, John E. Nielsen, Niels E. Skakkebæk, David Møbjerg Kristensen, Sofia B. Winge, Bernard Jégou, Antoine Rolland, Anne Jørgensen, Ewa Rajpert-De Meyts, Christian Janfelt
Publikováno v:
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.12866. ⟨10.1038/s41598-019-49177-y⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.12866. ⟨10.1038/s41598-019-49177-y⟩
Nielsen, J E, Rolland, A D, Rajpert-De Meyts, E, Janfelt, C, Jørgensen, A, Winge, S B, Kristensen, D M, Juul, A, Chalmel, F, Jégou, B & Skakkebæk, N E 2019, ' Characterisation and localisation of the endocannabinoid system components in the adult human testis ', Scientific Reports, vol. 9, no. 1, 12866 . https://doi.org/10.1038/s41598-019-49177-y
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, 2019, 9 (1), pp.12866. ⟨10.1038/s41598-019-49177-y⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.12866. ⟨10.1038/s41598-019-49177-y⟩
Nielsen, J E, Rolland, A D, Rajpert-De Meyts, E, Janfelt, C, Jørgensen, A, Winge, S B, Kristensen, D M, Juul, A, Chalmel, F, Jégou, B & Skakkebæk, N E 2019, ' Characterisation and localisation of the endocannabinoid system components in the adult human testis ', Scientific Reports, vol. 9, no. 1, 12866 . https://doi.org/10.1038/s41598-019-49177-y
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
International audience; Heavy use of cannabis (marijuana) has been associated with decreased semen quality, which may reflect disruption of the endocannabinoid system (ECS) in the male reproductive tract by exogenous cannabinoids. Components of ECS h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db07c2e62bd76eed9ce5b39cdb664e2
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02441400
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02441400
Autor:
Nina Mørup, Loa Nordkap, Stine A. Holmboe, Anders Juul, Niels E. Skakkebæk, Sofia B. Winge, M. Blomberg Jensen, Marianna Krause, Ulla Nordström Joensen, Lærke Priskorn, Katharina M. Main, Niels Jørgensen, Anne Kirstine Bang, Tina Kold Jensen, D. L. Egeberg Palme, Elisabeth Carlsen
Publikováno v:
Priskorn, L, Nordkap, L, Bang, A K, Krause, M, Holmboe, S A, Egeberg Palme, D L, Winge, S B, Mørup, N, Carlsen, E, Joensen, U N, Blomberg Jensen, M, Main, K M, Juul, A, Skakkebaek, N E, Jensen, T K & Jørgensen, N 2018, ' Average sperm count remains unchanged despite reduction in maternal smoking : results from a large cross-sectional study with annual investigations over 21 years ', Human Reproduction, vol. 33, no. 6, pp. 998-1008 . https://doi.org/10.1093/humrep/dey090
Study question How are temporal trends in lifestyle factors, including exposure to maternal smoking in utero, associated to semen quality in young men from the general population? Summary answer Exposure to maternal smoking was associated with lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e574be3fe3f7438ef64ab9afffff137
https://portal.findresearcher.sdu.dk/da/publications/401d98d6-03b9-4fb9-bdfe-7d9eb24c1cbd
https://portal.findresearcher.sdu.dk/da/publications/401d98d6-03b9-4fb9-bdfe-7d9eb24c1cbd
Autor:
Kirstine Belling, Jacob Malte Jensen, Marlene Danner Dalgaard, Lise Aksglaede, Anders Juul, Kristian Almstrup, Ewa Rajpert-De Meyts, Mikkel H. Schierup, Søren Brunak, John E Nielsen, Niels E. Skakkebæk, Sofia B. Winge
Publikováno v:
Cell Death & Disease
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death & Disease, vol. 9, no. 6, 671 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death and Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells ', Cell Death & Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death & Disease, vol. 9, no. 6, 671 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells article ', Cell Death and Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Winge, S B, Dalgaard, M D, Belling, K G, Jensen, J M, Nielsen, J E, Aksglaede, L, Schierup, M H, Brunak, S, Skakkebæk, N E, Juul, A, Rajpert-De Meyts, E & Almstrup, K 2018, ' Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells ', Cell Death & Disease, vol. 9, no. 6, 586 . https://doi.org/10.1038/s41419-018-0671-1
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
The most common human sex chromosomal disorder is Klinefelter syndrome (KS; 47,XXY). Adult patients with KS display a diverse phenotype but are nearly always infertile, due to testicular degeneration at puberty. To identify mechanisms causing the sel