Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Sofia Avnet"'
Autor:
Andrea Camisa, Giovanni Montanari, Andrea Testa, Luigi Falzetti, Sofia Avnet, Nicola Baldini, Giuseppe Notarstefano
Publikováno v:
IEEE Access, Vol 12, Pp 65310-65322 (2024)
Convolutional Neural Networks are being increasingly applied to the detection of anomalies in Computed Tomographies (CTs). The goal of this paper is to implement an automated Computer-Aided Detection (CADe) system for spinal lesions using CTs and Con
Externí odkaz:
https://doaj.org/article/df01d6d7df2c457abc5cbd851ce04bb0
Autor:
Tiziana Fischetti, Giorgia Borciani, Sofia Avnet, Katia Rubini, Nicola Baldini, Gabriela Graziani, Elisa Boanini
Publikováno v:
Nanomaterials, Vol 13, Iss 14, p 2040 (2023)
Reproducing in vitro a model of the bone microenvironment is a current need. Preclinical in vitro screening, drug discovery, as well as pathophysiology studies may benefit from in vitro three-dimensional (3D) bone models, which permit high-throughput
Externí odkaz:
https://doaj.org/article/f776e9418de54cad91e0b2db083b0262
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5294 (2023)
Epigenetic changes are heritable modifications that do not directly affect the DNA sequence. In cancer cells, the maintenance of a stable epigenetic profile can be crucial to support survival and proliferation, and said profile can differ significant
Externí odkaz:
https://doaj.org/article/d61e821c744d47c288c93c326d9ca429
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
As life expectancy increases, the population experiences progressive ageing. Ageing, in turn, is connected to an increase in bone-related diseases (i.e., osteoporosis and increased risk of fractures). Hence, the search for new approaches to study the
Externí odkaz:
https://doaj.org/article/9fa9a03a0ec04d8a8b56401eba34071d
Autor:
Gemma Di Pompo, Katsuyuki Kusuzaki, Marco Ponzetti, Vito Ferdinando Leone, Nicola Baldini, Sofia Avnet
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1904 (2022)
Current multimodal treatment of bone metastases is partially effective and often associated with side effects, and novel therapeutic options are needed. Acridine orange is a photosensitizing molecule that accumulates in acidic compartments. After pho
Externí odkaz:
https://doaj.org/article/e4af9cfc512a42c1ac565c50543c7275
Autor:
Gemma Di Pompo, Costantino Errani, Robert Gillies, Laura Mercatali, Toni Ibrahim, Jacopo Tamanti, Nicola Baldini, Sofia Avnet
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Bone metastasis (BM) is a dismal complication of cancer that frequently occurs in patients with advanced carcinomas and that often manifests as an osteolytic lesion. In bone, tumor cells promote an imbalance in bone remodeling via the release of grow
Externí odkaz:
https://doaj.org/article/22adb51a329f4ab8864534961bda888d
Autor:
Thomas GP Grünewald, Marta Alonso, Sofia Avnet, Ana Banito, Stefan Burdach, Florencia Cidre‐Aranaz, Gemma Di Pompo, Martin Distel, Heathcliff Dorado‐Garcia, Javier Garcia‐Castro, Laura González‐González, Agamemnon E Grigoriadis, Merve Kasan, Christian Koelsche, Manuela Krumbholz, Fernando Lecanda, Silvia Lemma, Dario L Longo, Claudia Madrigal‐Esquivel, Álvaro Morales‐Molina, Julian Musa, Shunya Ohmura, Benjamin Ory, Miguel Pereira‐Silva, Francesca Perut, Rene Rodriguez, Carolin Seeling, Nada Al Shaaili, Shabnam Shaabani, Kristina Shiavone, Snehadri Sinha, Eleni M Tomazou, Marcel Trautmann, Maria Vela, Yvonne MH Versleijen‐Jonkers, Julia Visgauss, Marta Zalacain, Sebastian J Schober, Andrej Lissat, William R English, Nicola Baldini, Dominique Heymann
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Abstract Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers. Although constituting only 1% of all human malignancies, sarcomas represent the second most common type of solid tumors in children and adolescents and compr
Externí odkaz:
https://doaj.org/article/32421af97ff64f339c73c8bfd6f57409
Autor:
Francesca Perut, Gabriela Graziani, Laura Roncuzzi, Nicoletta Zini, Sofia Avnet, Nicola Baldini
Publikováno v:
Cells, Vol 11, Iss 5, p 778 (2022)
Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents. Despite aggressive treatment regimens, the outcome is unsatisfactory, and multidrug resistance (MDR) is a pivotal process in OS treatment failure. OS-derived extrac
Externí odkaz:
https://doaj.org/article/4f5d637b31fe4d78b8add03a55ad5e57
Autor:
Sofia Avnet, Nicola Baldini, Lucie Brisson, Stine Falsig Pedersen, Paolo E. Porporato, Pierre Sonveaux, Gyorgy Szabadkai, Silvia Pastorekova
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The metabolism of cancer cells differs from that of their normal counterparts in a spectrum of attributes, including imbalances in diverse metabolic arms and pathways, metabolic plasticity and extent of adaptive responses, levels, and activities of m
Externí odkaz:
https://doaj.org/article/7b0c127d9cb0495a976802e704875ddd
Autor:
Gemma Di Pompo, Margherita Cortini, Roberto Palomba, Valentina Di Francesco, Elena Bellotti, Paolo Decuzzi, Nicola Baldini, Sofia Avnet
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5760 (2021)
In the tumor microenvironment, mesenchymal stromal cells (MSCs) are key modulators of cancer cell behavior in response to several stimuli. Intratumoral acidosis is a metabolic trait of fast-growing tumors that can induce a pro-tumorigenic phenotype i
Externí odkaz:
https://doaj.org/article/f210241c03224ac7b676df35740f3268