Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Sofia A Cerqueira"'
1
Akademický článek
Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA.
Autor: Aline C Habison, Marta Pires de Miranda, Chantal Beauchemin, Min Tan, Sofia A Cerqueira, Bruno Correia, Rajesh Ponnusamy, Edward J Usherwood, Colin E McVey, J Pedro Simas, Kenneth M Kaye
Publikováno v: PLoS Pathogens, Vol 13, Iss 9, p e1006555 (2017)
Many pathogens, including Kaposi's sarcoma herpesvirus (KSHV), lack tractable small animal models. KSHV persists as a multi-copy, nuclear episome in latently infected cells. KSHV latency-associated nuclear antigen (kLANA) binds viral terminal repeat
Externí odkaz: https://doaj.org/article/7c5642703ce84bb681186f9a7a5ad271
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2
Akademický článek
Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency.
Autor: Bruno Correia, Sofia A Cerqueira, Chantal Beauchemin, Marta Pires de Miranda, Shijun Li, Rajesh Ponnusamy, Lénia Rodrigues, Thomas R Schneider, Maria A Carrondo, Kenneth M Kaye, J Pedro Simas, Colin E McVey
Publikováno v: PLoS Pathogens, Vol 9, Iss 10, p e1003673 (2013)
Latency-associated nuclear antigen (LANA) mediates γ2-herpesvirus genome persistence and regulates transcription. We describe the crystal structure of the murine gammaherpesvirus-68 LANA C-terminal domain at 2.2 Å resolution. The structure reveals
Externí odkaz: https://doaj.org/article/e9ab2330f422454c8330e6d4aa52cb19
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5
Development of Triazoles and Triazolium Salts Based on AZT and Their Anti-Viral Activity against HIV-1
Autor: Andreia Teles Vieira, Ana Petronilho, Maria Inês P. S. Leitão, Paola Antenori, Giulia Francescato, Daniel Machado de Alencar, Helena Soares, Sofia A. Cerqueira, Juliana Gonçalves, Cruz Sebastião
Publikováno v: Molecules, Vol 26, Iss 6720, p 6720 (2021)
Molecules
Volume 26
Issue 21
We report herein a set of 3′-azido-3′-deoxythymidine (AZT) derivatives based on triazoles and triazolium salts for HIV-1 infection. The compounds were synthesized via click chemistry with Cu(I) and Ru(II) catalysts. Triazolium salts were synthesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a20f435ae1a178920279483223c055c
https://pubmed.ncbi.nlm.nih.gov/34771129
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6
Development of an electrochemical biosensor for Galectin-3 detection in point-of-care
Autor: M. Goreti F. Sales, Felismina T.C. Moreira, Rúben Fernandes, Sofia M.V. Cerqueira
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This research work aims the development and optimization of an electrochemical biosensor based on molecularly-imprinted polymers [MIPs], for monitoring a melanoma biomarker, Galectin-3 (Gal-3). As it is a multifunctional protein that plays an importa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02a5ade58dafa2f2eec892756a5b3a6
https://hdl.handle.net/10400.22/17946
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7
Uma técnica de bandagem modificada: experiência de um centro
Autor: Rui Castro, Sofia S. Cerqueira, Mónica R. Frutuoso, Joana M. Ferreira, Catarina Eusebio, Teresa Morgado
Publikováno v: Brazilian Journal of Nephrology v.43 n.1 2021
Jornal Brasileiro de Nefrologia
Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
Brazilian Journal of Nephrology, Volume: 43, Issue: 1, Pages: 41-46, Published: 11 NOV 2020
Brazilian Journal of Nephrology, Vol 43, Iss 1, Pp 41-46 (2020)
Brazilian Journal of Nephrology, Issue: ahead, Published: 11 NOV 2020
Background: A well-functioning vascular access is vital to patients on regular hemodialysis. Banding the access is indicated in high-flow-associated steal syndrome. It allows for the reduction of access flow while maintaining distal limb perfusion. N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a073809585f50b15eb2e2e11cacd9420
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000100041
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8
Development of Triazoles based on AZT and their Anti-Viral Activity Against HIV-1
Autor: Juliana Gonçalves, Sofia A. Cerqueira, Daniel Alencar, Helena Soares, Ana Petronilho
We report herein a set of 3’-azido-3’-deoxythymidine (AZT) derivatives based on triazoles and triazolium salts for HIV1 infection. Compounds were tested with □using HIV1 pre-exposure prophylaxis experimental model. All compounds were able to de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e91abb75f3d7463577dbf3bec59b15
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10
Estudo do sistema normativo contabilístico das microentidades: sua utilidade na perspetiva da entidade e dos profissionais da contabilidade
Autor: Araújo, Cátia Sofia Oliveira Cerqueira
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Dissertação de mestrado em Contabilidade
As micro e pequenas entidades assumem um papel importante na dinâmica económica de Portugal e da Europa, pela sua representatividade no tecido empresarial. Neste sentido, a União Europeia (UE) tem vi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::84bb8d9d68fae5b305315bb8e2b011f5
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