Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sofia, Omari"'
Autor:
Quentin Van Thillo, Jolien De Bie, Janith A. Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L. Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M. Marshall, Belamy B. Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Timothy G. Amos, Ira W. Deveson, Hannah McCalmont, Richard B. Lock, Ethan P. Oxley, Maximilian M. Garwood, Ross A. Dickins, Anne Uyttebroeck, Daniel R. Carter, Jan Cools, Charles E. de Bock
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SPI1 fusion genes in T-cell acute lymphoblastic leukemia (T-ALL) are commonly found with co-occurring NRAS mutations. Here, the authors show that the combination of these oncogenes is necessary to drive T-ALL in a murine model and that the oncogenic
Externí odkaz:
https://doaj.org/article/097bfb27edca4477bb37a09172ff1f71
Autor:
Ernest Moles, Christopher B. Howard, Pie Huda, Mawar Karsa, Hannah McCalmont, Kathleen Kimpton, Alastair Duly, Yongjuan Chen, Yizhou Huang, Melinda L. Tursky, David Ma, Sonia Bustamante, Russell Pickford, Patrick Connerty, Sofia Omari, Christopher J. Jolly, Swapna Joshi, Sylvie Shen, John E. Pimanda, Alla Dolnikov, Laurence C. Cheung, Rishi S. Kotecha, Murray D. Norris, Michelle Haber, Charles E. de Bock, Klaartje Somers, Richard B. Lock, Kristofer J. Thurecht, Maria Kavallaris
Publikováno v:
Science Translational Medicine. 15
High-risk childhood leukemia has a poor prognosis because of treatment failure and toxic side effects of therapy. Drug encapsulation into liposomal nanocarriers has shown clinical success at improving biodistribution and tolerability of chemotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc188efb9125cf1c20a439c99f70c47
https://doi.org/10.1126/scitranslmed.abm1262
https://doi.org/10.1126/scitranslmed.abm1262
Autor:
David T Yeung, Timothy P. Hughes, Deborah L. White, Sofia Omari, Paul Q. Thomas, Elyse C. Page, Susan L. Heatley, Charles E. de Bock, Laura N Eadie, Barbara J. McClure
Publikováno v:
Oncogene. 41:797-808
Refereed/Peer-reviewed The genetic basis of the predisposition for Down Syndrome (DS) patients to develop cytokine receptor-like factor 2 rearranged (CRLF2r) acute lymphoblastic leukemia (ALL) is currently unknown. Genes located on chromosome 21 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e7224b6c2caed7da39dd34f6589e6b
https://doi.org/10.1038/s41388-021-02126-4
https://doi.org/10.1038/s41388-021-02126-4
Autor:
Timothy G. Amos, Janith A. Seneviratne, Quentin Van Thillo, Hannah McCalmont, Wai L. Tam, Jan Cools, Ira W. Deveson, Jolien De Bie, Sofie Demeyer, Nancy Boeckx, Richard B. Lock, Vicki Zhai, Sarah Provost, Kiyotaka Isobe, Junko Takita, Anne Uyttebroeck, Heidi Segers, Olga Gielen, Daniel R. Carter, Ethan P. Oxley, Charles E. de Bock, Bram Sweron, Maximilian M. Garwood, Belamy B. Cheung, Glenn M. Marshall, Ross A. Dickins, Anushree Balachandran, Itaru Kato, Ellen Geerdens, Sofia Omari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Spi-1 Proto-Oncogene (SPI1) fusion genes are recurrently found in T-cell acute lymphoblastic leukemia (T-ALL) cases but are insufficient to drive leukemogenesis. Here we show that SPI1 fusions in combination with activating NRAS mutations drive an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4729d788d0d4d91953687b3a369bc0d1
https://doi.org/10.1038/s41467-021-24442-9
https://doi.org/10.1038/s41467-021-24442-9
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 3, Iss 1, Pp e2011018-e2011018 (2011)
Anemia is a common finding in lymphoma. There are few data available regarding the erythropoietin (EPO) levels in conjunction with ferritin in lymphoma patients. We prospectively evaluated 55 patients diagnosed with malignant lymphoma during the peri
Externí odkaz:
https://doaj.org/article/09e3ac51cabe4e009ffce0822139362e
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 3, Iss 1, Pp e2011018-e2011018 (2011)
Anemia is a common finding in lymphoma. There are few data available regarding the erythropoietin (EPO) levels in conjunction with ferritin in lymphoma patients. We prospectively evaluated 55 patients diagnosed with malignant lymphoma during the peri
Externí odkaz:
https://doaj.org/article/ba9a502bc3f447aca2a5ba0b13be73b2
Autor:
Anselm Enders, Zhijia Yu, Sergio D. Rosenzweig, Vicki Athanasopoulos, Mariam Nasreen, Sofia Omari, Vicky Cho, Hye Sun Kuehn, T. Daniel Andrews, Henry J. Sutton, Ian A. Cockburn, Christopher C. Goodnow, Hayley A. McNamara, Lisa A. Miosge, Debbie R. Howard, Brigette Boast, Yan Mei, Yovina Sontani
Publikováno v:
J Immunol
IKZF1 (IKAROS) is essential for normal lymphopoiesis in both humans and mice. Previous Ikzf1 mouse models have demonstrated the dual role for IKZF1 in both B and T cell development and have indicated differential requirements of each zinc finger. Fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43db8527dc7c6601a9e6f5324a59f1de
https://pubmed.ncbi.nlm.nih.gov/33658297
https://pubmed.ncbi.nlm.nih.gov/33658297
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases
Anemia is a common finding in lymphoma. There are few data available regarding the erythropoietin (EPO) levels in conjunction with ferritin in lymphoma patients. We prospectively evaluated 55 patients diagnosed with malignant lymphoma during the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01912e218aa37ef34b134d9f7f8ccb19
https://pubmed.ncbi.nlm.nih.gov/21713081
https://pubmed.ncbi.nlm.nih.gov/21713081
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 3, Iss 1, Pp e2011018-e2011018 (2011)
Anemia is a common finding in lymphoma. There are few data available regarding the erythropoietin (EPO) levels in conjunction with ferritin in lymphoma patients. We prospectively evaluated 55 patients diagnosed with malignant lymphoma during the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f393fd405189a7280f10f4bd2be360b
http://www.mjhid.org/article/view/7867
http://www.mjhid.org/article/view/7867