Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Sofia, Giorgetti"'
Autor:
Sara Raimondi, Giulia Faravelli, Paola Nocerino, Valentina Mondani, Alma Baruffaldi, Loredana Marchese, Maria Chiara Mimmi, Diana Canetti, Guglielmo Verona, Marianna Caterino, Margherita Ruoppolo, P. Patrizia Mangione, Vittorio Bellotti, Francesca Lavatelli, Sofia Giorgetti
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 11, Pp 484-505 (2023)
Abstract β2‐microglobulin (β2‐m) is a plasma protein derived from physiological shedding of the class I major histocompatibility complex (MHCI), causing human systemic amyloidosis either due to persistently high concentrations of the wild‐typ
Externí odkaz:
https://doaj.org/article/5149cb901be64b8ea5200c5f776cb102
Autor:
Francesca Re, Sofia Giorgetti, Barbara Biondi, Stefano Scapin, Francesco Mantegazza, Valeria Cassina, Silvia Maria Sesana, Laura Rizzi, Ivano Eberini, Luca Palazzolo, Marten Beeg, Marco Gobbi, Marco Sardina, Massimo Masserini
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractAim The effect of liposomes bi-functionalized with phosphatidic acid and with a synthetic peptide derived from human apolipoprotein E has been evaluated on the aggregation features of different amyloidogenic proteins: human Amyloid β1–40 (
Externí odkaz:
https://doaj.org/article/f28ca372cf6d4d4ab6a34ae319ebc629
Autor:
Giulia Faravelli, Valentina Mondani, P. Patrizia Mangione, Sara Raimondi, Loredana Marchese, Francesca Lavatelli, Monica Stoppini, Alessandra Corazza, Diana Canetti, Guglielmo Verona, Laura Obici, Graham W. Taylor, Julian D. Gillmore, Sofia Giorgetti, Vittorio Bellotti
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The globular to fibrillar transition of proteins represents a key pathogenic event in the development of amyloid diseases. Although systemic amyloidoses share the common characteristic of amyloid deposition in the extracellular matrix, they are clini
Externí odkaz:
https://doaj.org/article/78918c93ba684ff5a907851006159caf
Autor:
Cristina Cantarutti, Maria Chiara Mimmi, Guglielmo Verona, Walter Mandaliti, Graham W. Taylor, P. Patrizia Mangione, Sofia Giorgetti, Vittorio Bellotti, Alessandra Corazza
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1066 (2022)
The plasma protein transthyretin (TTR), a transporter for thyroid hormones and retinol in plasma and cerebrospinal fluid, is responsible for the second most common type of systemic (ATTR) amyloidosis either in its wild type form or as a result of des
Externí odkaz:
https://doaj.org/article/477b849ef091434591a20259defacbac
Autor:
Guglielmo Verona, P. Patrizia Mangione, Sara Raimondi, Sofia Giorgetti, Giulia Faravelli, Riccardo Porcari, Alessandra Corazza, Julian D. Gillmore, Philip N. Hawkins, Mark B. Pepys, Graham W. Taylor, Vittorio Bellotti
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Dissociation of the native transthyretin (TTR) tetramer is widely accepted as the critical step in TTR amyloid fibrillogenesis. It is modelled by exposure of the protein to non-physiological low pH in vitro and is inhibited by small molecule
Externí odkaz:
https://doaj.org/article/f338b2bcadbe45189416b0237ad95585
Autor:
Yamanappa Hunashal, Cristina Cantarutti, Sofia Giorgetti, Loredana Marchese, Federico Fogolari, Gennaro Esposito
Publikováno v:
Molecules, Vol 25, Iss 21, p 5187 (2020)
Background: The interaction between proteins and nanoparticles is a very relevant subject because of the potential applications in medicine and material science in general. Further interest derives from the amyloidogenic character of the considered p
Externí odkaz:
https://doaj.org/article/c07d3cc2588348b3af1c2ab9b838e43d
Autor:
Julien Marcoux, P Patrizia Mangione, Riccardo Porcari, Matteo T Degiacomi, Guglielmo Verona, Graham W Taylor, Sofia Giorgetti, Sara Raimondi, Sarah Sanglier‐Cianférani, Justin LP Benesch, Ciro Cecconi, Mohsin M Naqvi, Julian D Gillmore, Philip N Hawkins, Monica Stoppini, Carol V Robinson, Mark B Pepys, Vittorio Bellotti
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 10, Pp 1337-1349 (2015)
Abstract The mechanisms underlying transthyretin‐related amyloidosis in vivo remain unclear. The abundance of the 49–127 transthyretin fragment in ex vivo deposits suggests that a proteolytic cleavage has a crucial role in destabilizing the tetra
Externí odkaz:
https://doaj.org/article/73bd04162dae41c1a8592516fd43e2e6
Autor:
Andrea Francovich, Sara Raimondi, Loredana Marchese, Alma Baruffaldi, Sofia Giorgetti, Giulia Matrone
Publikováno v:
2022 IEEE International Ultrasonics Symposium (IUS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9458045e7fd07227e89cc565a9ecc5ec
https://doi.org/10.1109/ius54386.2022.9957328
https://doi.org/10.1109/ius54386.2022.9957328
Autor:
Sofia Giorgetti, Federico Fogolari, Yamanappa Hunashal, Gennaro Esposito, Loredana Marchese, Henriette Molinari, Neri Niccolai, Cristina Cantarutti
Publikováno v:
Physical Chemistry Chemical Physics. 22:6247-6259
The effect of extrinsic paramagnetic probes on NMR relaxation rates for surface mapping of proteins and other biopolymers is a widely investigated and powerful NMR technique. Here we describe a new application of those probes. It relies on the settin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928f079720f3f5c3dbe39a061b7ee8a
https://doi.org/10.1039/c9cp06950j
https://doi.org/10.1039/c9cp06950j
Autor:
Cristina Cantarutti, Yamanappa Hunashal, Carmelo La Rosa, Marcello Condorelli, Sofia Giorgetti, Vittorio Bellotti, Federico Fogolari, Gennaro Esposito
Publikováno v:
Physical chemistry chemical physics : PCCP. 24(3)
The nature of the nanoparticle-protein corona is emerging as a key aspect in determining the impact of nanomaterials on proteins and in general on the biological response. We previously demonstrated that citrate-stabilized gold nanoparticles (Cit-AuN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91e2486e3654a89ad7fcfce44da8f46
https://pubmed.ncbi.nlm.nih.gov/34951613
https://pubmed.ncbi.nlm.nih.gov/34951613