Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Sofia, Benfeito"'
Autor:
Daniel Chavarria, Anabela Borges, Sofia Benfeito, Lisa Sequeira, Marta Ribeiro, Catarina Oliveira, Fernanda Borges, Manuel Simões, Fernando Cagide
Publikováno v:
Journal of Advanced Research, Vol 54, Iss , Pp 251-269 (2023)
Introduction: The infections by multidrug-resistant bacteria are a growing threat to human health, and the efficacy of the available antibiotics is gradually decreasing. As such, new antibiotic classes are urgently needed. Objectives: This study aims
Externí odkaz:
https://doaj.org/article/154426b1e3e4496a97292a5db21dbeff
Autor:
Lisa Sequeira, Sofia Benfeito, Carlos Fernandes, Inês Lima, Joana Peixoto, Catarina Alves, Cláudia Sofia Machado, Alexandra Gaspar, Fernanda Borges, Daniel Chavarria
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 708 (2024)
Neurodegenerative diseases (NDs) are a set of progressive, chronic, and incurable diseases characterized by the gradual loss of neurons, culminating in the decline of cognitive and/or motor functions. Alzheimer’s disease (AD) and Parkinson’s dise
Externí odkaz:
https://doaj.org/article/4f4992fa6ba147229fcec8fab99b946a
Autor:
Daniel Martins, Eva Gil-Martins, Fernando Cagide, Catarina da Fonseca, Sofia Benfeito, Carlos Fernandes, Daniel Chavarria, Fernando Remião, Renata Silva, Fernanda Borges
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1158 (2023)
Mescaline derivative (2C phenethylamines) drugs have been modified by the introduction of a N-2-methoxybenzyl group to originate a new series of compounds with recognized and potent psychedelic effects, the NBOMe-drugs. Although they are prevalent in
Externí odkaz:
https://doaj.org/article/a70c7502d30a495f83dc6edd6e82b6e7
Autor:
Ricardo Amorim, Inês C.M. Simões, José Teixeira, Fernando Cagide, Yaiza Potes, Pedro Soares, Adriana Carvalho, Ludgero C. Tavares, Sofia Benfeito, Susana P. Pereira, Rui F. Simões, Agnieszka Karkucinska-Wieckowska, Ivan Viegas, Sylwia Szymanska, Michał Dąbrowski, Justyna Janikiewicz, Teresa Cunha-Oliveira, Agnieszka Dobrzyń, John G. Jones, Fernanda Borges, Mariusz R. Wieckowski, Paulo J. Oliveira
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102400- (2022)
Non-alcoholic fatty liver disease (NAFLD) is a health concern affecting 24% of the population worldwide. Although the pathophysiologic mechanisms underlying disease are not fully clarified, mitochondrial dysfunction and oxidative stress are key playe
Externí odkaz:
https://doaj.org/article/f512c15d747348f8a5a50917b0e4613a
Autor:
Inês Costa, Daniel José Barbosa, Vera Silva, Sofia Benfeito, Fernanda Borges, Fernando Remião, Renata Silva
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1369 (2023)
Ferroptosis is a type of regulated cell death promoted by the appearance of oxidative perturbations in the intracellular microenvironment constitutively controlled by glutathione peroxidase 4 (GPX4). It is characterized by increased production of rea
Externí odkaz:
https://doaj.org/article/3b7f4389adf149f3a5c05fcbbeafe0bc
Autor:
Vera Silva, Sofia Benfeito, Eva Gil-Martins, Inês Costa, Fernando Remião, Fernanda Borges, Renata Silva
Publikováno v:
RevSALUS, Vol 4, Iss Sup (2022)
Externí odkaz:
https://doaj.org/article/7e6cfab813c6481eb3ecb9419ebe3c84
Autor:
Cláudia M. Deus, Susana P. Pereira, Teresa Cunha-Oliveira, José Teixeira, Rui F. Simões, Fernando Cagide, Sofia Benfeito, Fernanda Borges, Nuno Raimundo, Paulo J. Oliveira
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102117- (2021)
Externí odkaz:
https://doaj.org/article/372f5d3391694b3ea23380b00bc73d1a
Autor:
Cláudia M. Deus, Susana P. Pereira, Teresa Cunha-Oliveira, José Teixeira, Rui F. Simões, Fernando Cagide, Sofia Benfeito, Fernanda Borges, Nuno Raimundo, Paulo J. Oliveira
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102037- (2021)
Parkinson's Disease (PD) is a neurodegenerative disorder affecting more than 10 million people worldwide. Currently, PD has no cure and no early diagnostics methods exist. Mitochondrial dysfunction is presented in the early stages of PD, and it is co
Externí odkaz:
https://doaj.org/article/0c864c71205c40f6b13e0df11e83cb0b
Autor:
Raffaella Catalano, Francesca Procopio, Daniel Chavarria, Sofia Benfeito, Stefano Alcaro, Fernanda Borges, Francesco Ortuso
Publikováno v:
Molecules, Vol 27, Iss 8, p 2467 (2022)
Human monoamine oxidases (hMAOs) are well-established targets for the treatment of neurological disorders such as depression, Parkinson’s disease and Alzheimer’s disease. Despite the efforts carried out over the years, few selective and reversibl
Externí odkaz:
https://doaj.org/article/3612b59cf6ab4be68541a96e339a8b56
Autor:
Sofia Benfeito, Carlos Fernandes, Daniel Chavarria, Sandra Barreiro, Fernando Cagide, Lisa Sequeira, José Teixeira, Renata Silva, Fernando Remião, Paulo J. Oliveira, Eugenio Uriarte, Fernanda Borges
Publikováno v:
Journal of Medicinal Chemistry. 66:1835-1851
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec758117ab79d4a661653f378b04e33
https://doi.org/10.1021/acs.jmedchem.2c01630
https://doi.org/10.1021/acs.jmedchem.2c01630