Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sofia, B Carvalho"'
Autor:
Sofia B. Carvalho, Ricardo J. S. Silva, Marcos F. Q. Sousa, Cristina Peixoto, António Roldão, Manuel J. T. Carrondo, Paula M. Alves
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine candidates. Nonetheless, their characterization is challenging due to VLPs’ unique biophysical and biochemical properties. To cope with such complexity, mu
Externí odkaz:
https://doaj.org/article/1941adabf729446ab0a5d18b8aee6648
Autor:
Sofia B Carvalho, Ricardo A Gomes, Anja Pfenninger, Martina Fischer, Michaela Strotbek, Inês A Isidro, Nihal Tugçu, Patrícia Gomes-Alves
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262711 (2022)
Quality control of biopharmaceuticals such as monoclonal antibodies (mAbs) has been evolving and becoming more challenging as the requirements of the regulatory agencies increase due to the demanding complexity of products under evaluation. Mass Spec
Externí odkaz:
https://doaj.org/article/45dbfe86c4cc4d048f8cf8fbf871f26a
Autor:
Rita P. Fernandes, José M. Escandell, Ana C. L. Guerreiro, Filipa Moura, Tiago Q. Faria, Sofia B. Carvalho, Ricardo J. S. Silva, Patrícia Gomes-Alves, Cristina Peixoto
Publikováno v:
Viruses, Vol 14, Iss 11, p 2539 (2022)
Virus-based biopharmaceutical products are used in clinical applications such as vaccines, gene therapy, and immunotherapy. However, their manufacturing remains a challenge, hampered by the lack of appropriate analytical tools for purification monito
Externí odkaz:
https://doaj.org/article/34eeeaa2f31843eba04fb9eeedc9f1a4
Autor:
Sofia B. Carvalho, Mafalda M. Dias, Jean-Philippe Matheise, Isabelle Knott, Patrícia Gomes-Alves, Paula M. Alves
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1585 (2022)
Rotavirus A infection is a global leading cause of severe acute gastroenteritis associated with life-threatening diarrheal episodes in infants and young children. The disease burden is being reduced, namely due to a wider access to rotavirus vaccines
Externí odkaz:
https://doaj.org/article/b893c620330c41f1a4955763ec0cee07
Autor:
José Escandell, Filipa Moura, Sofia B. Carvalho, Ricardo J. S. Silva, Ricardo Correia, Antonio Roldão, Patrícia Gomes‐Alves, Paula M. Alves
Publikováno v:
Biotechnology and Bioengineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0231d7415f4e4cd89d39853141fce8e4
https://doi.org/10.1002/bit.28394
https://doi.org/10.1002/bit.28394
Autor:
Sofia B Carvalho, Ana Sofia Moreira, Joana Gomes, Manuel J T Carrondo, David J Thornton, Paula M Alves, Julia Costa, Cristina Peixoto
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190974 (2018)
Mucins are high-molecular weight glycoproteins (0.25-20 MDa) containing one or more domains that are heavily O-glycosylated. Their implications as targets for cancer treatment have increased the interest in these glycoproteins, mainly in the fields o
Externí odkaz:
https://doaj.org/article/8b7fc453b85140798b462b6e160d5fba
Autor:
Joana Gomes, Patrícia Gomes-Alves, Sofia B. Carvalho, Cristina Peixoto, Paula M. Alves, Peter Altevogt, Julia Costa
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1741-1761 (2015)
Cells release vesicles to the extracellular environment with characteristic nucleic acid, protein, lipid, and glycan composition. Here we have isolated and characterized extracellular vesicles (EVs) and total cell membranes (MBs) from ovarian carcino
Externí odkaz:
https://doaj.org/article/13bc106ab2a94a8ca38de32d1a384fc1
Autor:
Sofia B. Carvalho, Ricardo J. S. Silva, Marcos F. Q. Sousa, Cristina Peixoto, António Roldão, Manuel J. T. Carrondo, Paula M. Alves
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine candidates. Nonetheless, their characterization is challenging due to VLPs’ unique biophysical and biochemical properties. To cope with such complexity, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd5ef5d7cf9fa07bf022769ebf181c3
https://pubmed.ncbi.nlm.nih.gov/35252128
https://pubmed.ncbi.nlm.nih.gov/35252128
Autor:
Jose M Escandell, Daniel AM Pais, Sofia B Carvalho, Karen Vincent, Patrícia Gomes-Alves, Paula M Alves
Publikováno v:
Current opinion in biotechnology. 74
Recombinant adeno-associated (rAAV) vector-based gene therapy has been the focus of intense research driven by the safety profile and several recent clinical breakthroughs. As of April 2021, there are two rAAV-based gene therapies approved and more t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07319ff8dc3fcad29dc67c40ad38353
https://pubmed.ncbi.nlm.nih.gov/35007989
https://pubmed.ncbi.nlm.nih.gov/35007989
Autor:
Cristina Peixoto, Paula M. Alves, Alex Xenopoulos, Manuel J.T. Carrondo, João J. Clemente, Sofia B. Carvalho, Ana S. P. Moreira, Ricardo J.S. Silva, Bárbara Cunha
Publikováno v:
Separation and Purification Technology. 218:81-88
Vaccination remains the most effective available tool for preventing influenza infection, which affects millions of people annually. The virus is constantly mutating, requiring annual immunization. Vaccine production should be achieved in a very shor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::290500a53bcccb041d5cf24b6c42f1f0
https://doi.org/10.1016/j.seppur.2019.02.040
https://doi.org/10.1016/j.seppur.2019.02.040