Výsledky vyhledávání - "Sofía Campillo de Blas"

MO610: A Graphene-Based Bioactive Compound Reduces Adipogenesis and Increases Lipolysis Via Integrin-Beta1 Interaction: A New Therapeutical Approach Against Obesity

Autor: Mercedes Griera-Merino, María del Prado Lavin-Lopez, Sofía Campillo de Blas, Elena Gutiérrez-Calabrés, Laura Calleros, Martin Martinez, Jose Martinez, Manuel Rodriguez-Puyol, Diego Rodríguez-Puyol, Sergio De Frutos García

Publikováno v: Nephrology Dialysis Transplantation. 37

BACKGROUND AND AIMS Type 2 diabetes and obesity are metabolic disorders related to kidney risk and associated with white adipose tissue (WAT) hypertrophy, which is based in a pro-adipogenic transdifferentiation of the adipocytes and their precursors�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26915109f17d232e4a7e90e195983538
https://doi.org/10.1093/ndt/gfac076.003

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P0980IMPLICATIONS OF ADIPOSE EARLY DOWNREGULATION OF INTEGRIN-LINKED KINASE (ILK) IN THE DEVELOPMENT OF METABOLIC SYNDROME IN MICE

Autor: Laura Calleros, Diego García-Ayuso, Mercedes Griera-Merino, Manuel Rodríguez-Puyol, Sergio De Frutos García, Diego Rodríguez-Puyol, Sofía Campillo de Blas, Lourdes Bohorquez Magro, Marta Barrionuevo-González, Elena Gutiérrez-Calabrés

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Insulin resistance (IR)-related metabolic disorders, such as diabetes type 2 and obesity, are linked to renal and cardiovascular risk. Unfortunately, they lack a better prognosis before their full establishment. An important mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::540b2ebec08845a3c588dad0a5755924
https://doi.org/10.1093/ndt/gfaa142.p0980

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P0675LEUCOCYTE PODOSOME FORMATION AND ADHESION TO ENDOTHELIUM IS MEDIATED BY INTEGRIN LINKED KINASE IN CHRONIC KIDNEY DISEASE (CKD)

Autor: Elena Gutiérrez-Calabrés, Sergio De Frutos García, Mercedes Griera-Merino, David Vaillo, Diego García Ayuso, Laura Calleros, Sofía Campillo de Blas, M. Rodriguez-Puyol, Lourdes Bohorquez Magro, Diego Rodríguez-Puyol

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Patients with CKD have a higher risk of developing cardiovascular diseases. Protein-bound uremic toxins, such as p-cresol (pc) and indoxyl-sulfate (IS), are retention solutes, poorly removed during hemodialysis. They lead to endot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8be63bb1a4e3f31260ada77d1ada5bdb
https://doi.org/10.1093/ndt/gfaa142.p0675

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P0020THE NEPHRO-PROTECTIVE ROUTE OF CGMP DOES NOT COMPENSATE NPRHOGENIC DIABETES INSIPIDUS, BOTH CONDITIONS MEDIATED BY RENAL INTEGRIN LINKED KINASE (ILK)

Autor: Laura Calleros, Mercedes Griera-Merino, Lourdes Bohorquez Magro, Diego Rodríguez-Puyol, Diego García-Ayuso, Marta Barrionuevo-González, Sergio De Frutos García, Elena Gutiérrez-Calabrés, Sofía Campillo de Blas, M. Rodriguez-Puyol

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Renal ILK transgenic deletion on mice (cKD-ILK) address basal polyuria compatible with nephrogenic diabetes insipidus (NDI), due to disrupted tubular water channel aquaporin 2 (AQP2) AQP2 expression and vesicular trafficking to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::161d0d63581973142db3fbb9c7817ffb
https://doi.org/10.1093/ndt/gfaa142.p0020

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P0992PHARMACOLOGICAL UPREGULATION OF INTEGRIN-LINKED KINASE (ILK) REDUCES VISCERAL ADIPOSITY IN A METABOLIC SYNDROME MICE MODEL

Autor: Sofía Campillo de Blas, Mercedes Griera-Merino, Lourdes Bohorquez Magro, Manuel Rodríguez-Puyol, Laura Calleros, David Vaillo, Diego Rodríguez-Puyol, Diego García-Ayuso, Elena Gutiérrez-Calabrés, Sergio De Frutos García

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Important mechanism associated to the development of Insulin resistance (IR) are dysregulation of lipid adjustment and excessive deposition of extracellular matrix (ECM) in the visceral white adipose tissue (WAT). The transgenic d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf7a9d6b426d9ed27647866e7ba449d7
https://doi.org/10.1093/ndt/gfaa142.p0992

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P0672CALPAINS 1 AND 2 ARE INCREASED DURING THE DEVELOPMENT OF CHRONIC KIDNEY DAMAGE IN MICE FED WITH AN ADENINE RICH DIET

Autor: Elena Gutiérrez-Calabrés, Manuel Rodríguez-Puyol, Sergio De Frutos García, Laura Calleros, Diego Rodríguez-Puyol, Mercedes Griera-Merino, Sofía Campillo de Blas, Diego García Ayuso, Lourdes Bohorquez Magro, David Vaillo

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Calpains are intracellular cysteine proteases that play a critical role in cell remodeling, being involved in multiple biological processes linked to tissue damage and repair mechanisms. In addition, they are released into the cir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::941196c6b505d4039c6745eaff1f2708
https://doi.org/10.1093/ndt/gfaa142.p0672

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Efecto protector de la deleción de la quinasa ligada a integrinas (ILK) en la fibrosis y el daño vascular asociado a la enfermedad renal crónica

Autor: Sergio de Frutos, Laura Calleros, Sofía Campillo de Blas, Lourdes Bohorquez, Mercedes Griera, Manuel Rodríguez Puyol, Diego García Ayuso, Diego Rodríguez Puyol

Publikováno v: Dianas. 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fd9884f3e1f8bf3e540fc341d5b8309
https://doi.org/10.37536/dianas.2019.8.1.24

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