Insight into the catalytic mechanism of thymidylate synthase ThyX of Campylobacter jejuni

Autor: Sodolescu, S. A., Graziani, Sébastien, Boum, Y., Myllykallio, H., Liebl, Ursula

Publikováno v: Zoonoses and public health
14th International Workshop on Campylobacter, Helicobacter and Related Organisms
14th International Workshop on Campylobacter, Helicobacter and Related Organisms, Sep 2007, Rotterdam, Netherlands. pp.55

International audience; For de novo synthesis of the essential DNA precursor dTMP, Campylobacter jejuni uses a novel thymidylate synthase, named ThyX (1). Different from canonical dimeric thymidylate synthase ThyA, ThyX is a flavoprotein and an acti

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https://hal-polytechnique.archives-ouvertes.fr/hal-00841068