Zobrazeno 1 - 10
of 4 454
pro vyhledávání: '"Sodium valproate"'
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 83-86 (2024)
Status epilepticus (SE) is a life-threatening neurological condition with significant mortality. Rapid management is essential to minimize the mortality and disability of SE. Two recent trials provided evidence to guide SE management in early and est
Externí odkaz:
https://doaj.org/article/b378b63fc1674e1290de10258e9ce4d6
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 16, Iss 2, Pp 104-109 (2024)
Objective: to investigate the effects of sodium valproate on plasma concentrations of homocysteine, folate and vitamin B12 levels in epileptic patients with long-standing tonic-clonic seizures compared to newly diagnosed epileptic patients and health
Externí odkaz:
https://doaj.org/article/0c292e9ada2048d4b940c070e8befbd0
Autor:
Mohammad Hadi Zarei, Sami Akbulut, Maryam Zafari, Elham Saghaei, Zahra Lorigooini, Hossein Amini Khoei, Somaye Khosravi, Elham Bijad
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 7, Pp 298-306 (2024)
Objective: To explore the effect of black radish (Raphanus sativus L. var niger) root extract on liver enzymes, oxidative stress, and histopathological alterations in mice with sodium valproate-induced hepatotoxicity. Methods: Thirty-two mice were di
Externí odkaz:
https://doaj.org/article/571ec2faee9941d086d6b5795149f8e6
Publikováno v:
Current Medicine Research and Practice, Vol 14, Iss 4, Pp 178-180 (2024)
Drug-induced vasculitis is essentially a small-vessel vasculitis. Histopathological changes in this condition are characterised by neutrophilic leucocytoclasia of the small vessels. To label it leucocytoclastic vasculitis, one must exclude other type
Externí odkaz:
https://doaj.org/article/e96b2d1f506644d6acff197a741bdc93
Publikováno v:
Journal of Medical and Scientific Research, Vol 11, Iss 4, Pp 329-335 (2023)
Long-term therapy with antiseizure medications (ASMs) has been associated with metabolic consequences that lead to an increase in the risk of atherosclerosis in patients with epilepsy. This study was conducted to assess the effects of ASMs on vascula
Externí odkaz:
https://doaj.org/article/5a15f020c47147ff8f03463ecf5d57c0
Publikováno v:
Zhongguo quanke yixue, Vol 26, Iss 23, Pp 2918-2922 (2023)
Background Epilepsy is a chronic episodic brain disorder with a high incidence and can seriously affect the quality of life of the patients. Therefore, timely treatment to control seizures is particularly important. Numerous studies have shown the ef
Externí odkaz:
https://doaj.org/article/e5ce8338d0a940b3b5b5dc825ec0d040
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
Autor:
Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N. Rich, Xingjiang Yu
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is a lethal cancer characterized by hypervascularity and necrosis associated with hypoxia. Here, it is found that hypoxia preferentially induces the actin‐binding protein, Transgelin (TAGLN), in GBM stem cells (GSCs). Me
Externí odkaz:
https://doaj.org/article/95216e81a5c74d7e8e6af9ccdf165215
Autor:
Raymond L. Benza, Philip B. Adamson, Deepak L. Bhatt, Fredrik Frick, Gunnar Olsson, Niklas Bergh, Björn Dahlöf
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Although rare, pulmonary arterial hypertension (PAH) is associated with substantial morbidity and a median survival of approximately 7 years, even with treatment. Current medical therapies have a primarily vasodilatory effect and do not modi
Externí odkaz:
https://doaj.org/article/ba9468a5ec3649d2ad1715aea913abbe
Autor:
Donatas Stakišaitis, Linas Kapočius, Vacis Tatarūnas, Dovydas Gečys, Auksė Mickienė, Tomas Tamošuitis, Rasa Ugenskienė, Arūnas Vaitkevičius, Ingrida Balnytė, Vaiva Lesauskaitė
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 409 (2024)
The study presents data on the anti-inflammatory effects of a combination of sodium dichloroacetate and sodium valproate (DCA–VPA) on the expression of inflammation- and immune response-related genes in T lymphocytes of SARS-CoV-2 patients. The stu
Externí odkaz:
https://doaj.org/article/3c81022d5d2e48e59e7831dd725cf388
Publikováno v:
Biomedical and Biotechnology Research Journal, Vol 7, Iss 2, Pp 225-232 (2023)
Background: One of the metabolic processes of sodium valproate (SV) metabolism is cytochrome P450 (CYP)-mediated oxidation. Polymorphism of the genes coding CYP enzymes can cause the changes in steady state SV concentration and clinical outcome. The
Externí odkaz:
https://doaj.org/article/03c9a666e096414fad5e286410ee13d5