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Publikováno v:
Regenerative Therapy, Vol 17, Iss, Pp 8-12 (2021)
Regenerative Therapy
Regenerative Therapy
Recent studies have revealed that cancer stem cells (CSCs) undergo metabolic alterations that differentiate them from non-CSCs. Inhibition of specific metabolic pathways in CSCs has been conducted to eliminate the CSC population in many types of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6e792e0488411d444bcff6479bbf43
https://doi.org/10.1016/j.reth.2021.01.005
https://doi.org/10.1016/j.reth.2021.01.005
Autor:
King Ming Chan, Man Long Kwok
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 822-835 (2020)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Oxidative stress and apoptosis created by Cu2+ and Cd2+ insults were studied in ZFL. • Cu2+ and Cd2+ both created lipid peroxidation, causing oxidative stress in cytoplasm. • Mitochondrial superoxide was ind
Highlights • Oxidative stress and apoptosis created by Cu2+ and Cd2+ insults were studied in ZFL. • Cu2+ and Cd2+ both created lipid peroxidation, causing oxidative stress in cytoplasm. • Mitochondrial superoxide was ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0402719444dde34edacafe8222a5be9
http://www.sciencedirect.com/science/article/pii/S2214750020303474
http://www.sciencedirect.com/science/article/pii/S2214750020303474
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 737-745 (2019)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Health span is driven by a precise interplay between genes and the environment. Cell response to environmental cues is mediated by signaling cascades and genetic variants that affect gene expression by regulating chromatin plasticity. Indeed, they ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360c46f2a9feadbc0fa07938930830c6
http://www.sciencedirect.com/science/article/pii/S2001037019301011
http://www.sciencedirect.com/science/article/pii/S2001037019301011
Autor:
Jun Liu, Huiping Chen, Xiaorong Ma, Miao Xu, Yan Xiao, Tianxiang Ouyang, Tao Liu, Yingying Huang
Publikováno v:
Redox Biology, Vol 20, Iss, Pp 195-203 (2019)
Redox Biology
Redox Biology
Keloids exhibit cancer-like properties without spontaneous regression and usually recur post excision. Although photodynamic therapy (PDT) is a promising treatment, details of the mechanisms remain to be elucidated. In this study, we investigated mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce027f62fcf76b55a0ab9c9471d7b84e
http://www.sciencedirect.com/science/article/pii/S2213231718308140
http://www.sciencedirect.com/science/article/pii/S2213231718308140
Autor:
Hongquan Guo, Xinfeng Liu, Juanji Li, Xiaolei Shi, Yi Xie, Pengfei Xu, Yunzi Li, Qian Liu, Rui Sun, Ye Hong, Mengna Peng, Gelin Xu
Publikováno v:
Redox Biology
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)
Cellular oxidative stress plays a vital role in the pathological process of neural damage in cerebral ischemia/reperfusion (I/R). The breast cancer susceptibility protein 1 (BRCA1), a tumor suppressor, can modulate cellular antioxidant response and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e034e7c5102b1e7cd98f372f511aac
https://doi.org/10.1016/j.redox.2018.06.012
https://doi.org/10.1016/j.redox.2018.06.012
Autor:
Ya Han Wang, Ming Derg Lai, Shao Ming Wang, Chiung Yuan Ko, Sher Wei Lim, Ju Ming Wang, Hong Yi Lin
Publikováno v:
Redox Biology
Redox Biology, Vol 16, Iss, Pp 104-112 (2018)
Redox Biology, Vol 16, Iss, Pp 104-112 (2018)
Excessive reactive oxygen species (ROS) can form an oxidative stress and an associated neuroinflammation. However, the contribution of astrocytes to ROS formation, the cause of the resistance of astrocytes to oxidative stress, and the consequences on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1fa650a3403f4a51ea9f08f2622ac0
https://doi.org/10.1016/j.redox.2018.02.011
https://doi.org/10.1016/j.redox.2018.02.011
Autor:
Jia-Jian Liang, Yanxuan Xu, Yao Yao, Shao-Lang Chen, Di Ma, Vishal Jhanji, Tsz Kin Ng, Xiang-Ling Yuan
Publikováno v:
Experimental Eye Research
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen for coronavirus disease 2019 (COVID-19) pandemic. Its infection depends on the binding of spike protein to the host cell receptor angiotensin-converting enzyme 2 (ACE2), typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc1b2f2b5c07bdbdc8e2328a2bfcbd7
http://europepmc.org/articles/PMC8610570
http://europepmc.org/articles/PMC8610570
Autor:
Ana I. Duarte, Paula I. Moreira, Brígida R. Pinho, Paula M. Canas, Jorge M.A. Oliveira, Michael P. Murphy
Publikováno v:
Free Radical Biology & Medicine
Abnormal protein homeostasis (proteostasis), dysfunctional mitochondria, and aberrant redox signalling are often associated in neurodegenerative disorders, such as Huntington's (HD), Alzheimer's and Parkinson's diseases. It remains incompletely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85870a24e4f74069ffd8b43a7a0a2113
https://pubmed.ncbi.nlm.nih.gov/31751762
https://pubmed.ncbi.nlm.nih.gov/31751762
Autor:
Ruijuan Guan, Defu Li, Jian Wang, Hongwei Yao, Ziying Li, Zhou Cai, Wenju Lu, Bingxian Deng, Jingyi Xu, Lan Wang, Wei Liu, Yuanyuan Li
Publikováno v:
Redox Biology
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology, Vol 28, Iss, Pp-(2020)
Airway remodeling is one of the characteristics for chronic obstructive pulmonary disease (COPD). The mechanism underlying airway remodeling is associated with epithelial-mesenchymal transition (EMT) in the small airways of smokers and patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d28260ebccf7084f4489ee28730a2a3
https://pubmed.ncbi.nlm.nih.gov/31704583
https://pubmed.ncbi.nlm.nih.gov/31704583