Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Socrates J, Tzartos"'
Autor:
Maria Pechlivanidou, Aigli G. Vakrakou, Katerina Karagiorgou, Erdem Tüzün, Eleni Karachaliou, Elisabeth Chroni, Theodora Afrantou, Nikolaos Grigoriadis, Christina Argyropoulou, Nikolaos Paschalidis, Elif Şanlı, Aikaterini Tsantila, Maria Dandoulaki, Elpinickie I. Ninou, Paraskevi Zisimopoulou, Renato Mantegazza, Francesca Andreetta, Leon Dudeck, Johann Steiner, Jon Martin Lindstrom, Dimitrios Tzanetakos, Konstantinos Voumvourakis, Sotirios Giannopoulos, Georgios Tsivgoulis, Socrates J. Tzartos, John Tzartos
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNeuronal nicotinic acetylcholine receptors (nAChRs) are abundant in the central nervous system (CNS), playing critical roles in brain function. Antigenicity of nAChRs has been well demonstrated with antibodies to ganglionic AChR subtypes (i
Externí odkaz:
https://doaj.org/article/cbeea397cd8a4640a4b8545fc2095394
Autor:
Nikolaos Alexandris, George Lagoumintzis, Christos T. Chasapis, Demetres D. Leonidas, Georgios E. Papadopoulos, Socrates J. Tzartos, Aristidis Tsatsakis, Elias Eliopoulos, Konstantinos Poulas, Konstantinos Farsalinos
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 73-83 (2021)
SARS-CoV-2 infection was announced as a pandemic in March 2020. Since then, several scientists have focused on the low prevalence of smokers among hospitalized COVID-19 patients. These findings led to our hypothesis that the Nicotinic Cholinergic Sys
Externí odkaz:
https://doaj.org/article/5333e520de9c4479bba15c122c07e864
Autor:
John S. Tzartos, Fotini Boufidou, Christos Stergiou, Jens Kuhle, Eline Willemse, Lina Palaiodimou, Ioanna Tsantzali, Eleni Sideri, Anastasios Bonakis, Sotirios Giannopoulos, Konstantinos I. Voumvourakis, Georgios Tsivgoulis, Socrates J. Tzartos, Elisabeth Kapaki, George P. Paraskevas
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1099 (2022)
Blood phospho-tau181 may offer a useful biomarker for Alzheimer’s disease. However, the use of either serum or plasma phospho-tau181 and their diagnostic value are currently under intense investigation. In a pilot study, we measured both serum and
Externí odkaz:
https://doaj.org/article/9e86c34c305642c1b09e892f76e67ecf
Autor:
Petros Giastas, Athanasios Papakyriakou, George Tsafaras, Socrates J. Tzartos, Marios Zouridakis
Publikováno v:
Molecules, Vol 27, Iss 14, p 4642 (2022)
The β3 subunit of nicotinic acetylcholine receptors (nAChRs) participates in heteropentameric assemblies with some α and other β neuronal subunits forming a plethora of various subtypes, differing in their electrophysiological and pharmacological
Externí odkaz:
https://doaj.org/article/86ba670c9d164cdfaefeea9be2c1d24a
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Myasthenia gravis (MG) is the most common autoimmune disorder affecting the neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is caused by autoantibodies targeting proteins of the neuromuscular junction; ~85% of M
Externí odkaz:
https://doaj.org/article/3c356c2b1cbc4475adfdfdc69143d5b2
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by autoantibodies targeting neuromuscular junction proteins. In the majority of patient
Externí odkaz:
https://doaj.org/article/b1a455b221f543c0b51c6aaff2171932
Autor:
Elias Thodis, Apostolia Topaloudi, Marianthi Georgitsi, Socrates J. Tzartos, Melanie B. Martinez, John G. Yovos, Peristera Paschou, Xanthippi Tsekmekidou, George Lagoumintzis, Fotis Tsetsos, Alyssa Camille Flint, John A. Stamatoyannopoulos, Stefanos Roumeliotis, Zhiyu Yang, Marios Theodoridis, Stylianos Panagoutsos, Eleni Zamba-Papanicolaou, Ploumis Passadakis, Efstratios Maltezos, John Tzartos, Zoi Zagoriti, Yiolanda-Panayiota Christou, Kalliopi Kotsa, Dimitrios Papazoglou, Evangelia Yannaki, Nikolaos Papanas, Konstantinos Poulas, Kleopas A. Kleopa, Athanasios Roumeliotis
Publikováno v:
Journal of Medical Genetics. 59:801-809
BackgroundMyasthenia gravis (MG) is a rare autoimmune disorder affecting the neuromuscular junction (NMJ). Here, we investigate the genetic architecture of MG via a genome-wide association study (GWAS) of the largest MG data set analysed to date.Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b550f29c5b4f688b8a9b07d6d74953f0
https://doi.org/10.1136/jmedgenet-2021-107953
https://doi.org/10.1136/jmedgenet-2021-107953
Autor:
Konstantinos Farsalinos, Socrates J. Tzartos, Elias Eliopoulos, Georgios Papadopoulos, Nikolaos Alexandris, Aristidis Tsatsakis, Konstantinos Poulas, Demetres D. Leonidas, Christos T. Chasapis, George Lagoumintzis
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 73-83 (2021)
Toxicology Reports
Toxicology Reports
SARS-CoV-2 infection was announced as a pandemic in March 2020. Since then, several scientists have focused on the low prevalence of smokers among hospitalized COVID-19 patients. These findings led to our hypothesis that the Nicotinic Cholinergic Sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfd37606e9532bfe51cb8879607ba7d
https://doi.org/10.1016/j.toxrep.2020.12.013
https://doi.org/10.1016/j.toxrep.2020.12.013
Autor:
Elena V. Kryukova, Igor A. Ivanov, Dmitry S. Lebedev, Ekaterina N. Spirova, Natalia S. Egorova, Marios Zouridakis, Igor E. Kasheverov, Socrates J. Tzartos, Victor I. Tsetlin
Publikováno v:
Marine Drugs, Vol 16, Iss 12, p 460 (2018)
α-Conotoxins from Conus snails are capable of distinguishing muscle and neuronal nicotinic acetylcholine receptors (nAChRs). α-Conotoxin RgIA and αO-conotoxin GeXIVA, blocking neuronal α9α10 nAChR, are potential analgesics. Typically, α-conotox
Externí odkaz:
https://doaj.org/article/4baca4d9b0c5468eb3e26107218a6f96
Autor:
Ia Iagorshvili, Victor I. Tsetlin, Ramaz Katsarava, Ekaterina N. Spirova, Dmitry S. Lebedev, Igor E. Kasheverov, Elizaveta Yu. Tufanova, Natalia S. Egorova, Nikita D. Timofeev, Elena V. Kryukova, Nino Zavradashvili, Igor Ivanov, Andrei E. Siniavin, Marios Zouridakis, Socrates J. Tzartos, Denis S. Kudryavtsev
Publikováno v:
Molecular Pharmacology. 96:664-673
Many peptide ligands of nicotinic acetylcholine receptors (nAChRs) contain a large number of positively charged amino acid residues, a striking example being conotoxins RgIA and GeXIVA from marine mollusk venom, with an arginine content of >30%. To d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ca78c83ee18a3a5feeb9828fc555c2
https://doi.org/10.1124/mol.119.117713
https://doi.org/10.1124/mol.119.117713