Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sock Hong Seah"'
Publikováno v:
Cells, Vol 10, Iss 11, p 3130 (2021)
Cancer is a global health problem. The delineation of molecular mechanisms pertinent to cancer initiation and development has spurred cancer therapy in the form of precision medicine. The Hippo signalling pathway is a tumour suppressor pathway implic
Externí odkaz:
https://doaj.org/article/3fbd9eb42596497987797ce2776e1413
Autor:
Darren Chen Pei Wong, Catherine Qiurong Pan, Shi Yin Er, T. Thivakar, Tan Zi Yi Rachel, Sock Hong Seah, Pei Jou Chua, Tingting Jiang, Ti Weng Chew, Parthiv Kant Chaudhuri, Somsubhro Mukherjee, Agus Salim, Thike Aye Aye, Cheng Gee Koh, Chwee Teck Lim, Puay Hoon Tan, Boon Huat Bay, Anne J. Ridley, Boon Chuan Low
Publikováno v:
Molecular biology of the cell.
Rho GTPases regulate cell morphogenesis and motility under the tight control of guanine-nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). However, the underlying mechanism(s) that coordinate their spatiotemporal activities, wh
Publikováno v:
Proceedings of the Singapore National Academy of Science. 14:3-13
WW-domain binding protein 2 (WBP2) was first discovered as a ligand of the WW-domain of Yes-associated Protein (YAP). A decade after its discovery, our laboratory implicated WBP2 in breast cancer development. Since then, WBP2 had also been shown to b
Publikováno v:
Cells, Vol 10, Iss 3130, p 3130 (2021)
Cells
Cells
Cancer is a global health problem. The delineation of molecular mechanisms pertinent to cancer initiation and development has spurred cancer therapy in the form of precision medicine. The Hippo signalling pathway is a tumour suppressor pathway implic
Publikováno v:
Life Science Alliance
WBP2 protein blocks the microRNA biogenesis via physical interactions with the microprocessor complex, and reverts the tumor-suppressive role of DGCR8.
WBP2 is an emerging oncoprotein with diverse functions in breast tumorigenesis via regulating
WBP2 is an emerging oncoprotein with diverse functions in breast tumorigenesis via regulating
Publikováno v:
Life Science Alliance; Jul2021, Vol. 4 Issue 7, p1-14, 14p