Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sock Hoai Chan"'
Autor:
Zewen Zhang, Nur Diana Binte Ishak, Frances Victoria Fajardo Que, Zi Yang Chua, Sock Hoai Chan, Jianbang Chiang, Joanne Ngeow Yuen Yie
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 21, Iss 1, Pp 1-7 (2023)
Abstract Background Although Singapore is one of the highest vaccinated countries in the world, vaccine hesitancy remains in a subpopulation, including individuals with cancer predisposition syndromes. At the Cancer Genetics Service National Cancer C
Externí odkaz:
https://doaj.org/article/ae888eca3b09467ba0b29a36e2e8a89b
Autor:
Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, SG10K_Health Consortium, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C. Chambers, E-Shyong Tai, Patrick Tan, Saumya S. Jamuar, Joanne Ngeow, Weng Khong Lim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.
Externí odkaz:
https://doaj.org/article/117b09c793b9435cbcba4527a4883feb
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Although CDKN2A is well-known as a susceptibility gene for melanoma and pancreatic cancer, germline variants have also been anecdotally associated with a broader range of neoplasms including neural system tumors, head and neck squamous cell
Externí odkaz:
https://doaj.org/article/4db9070c34c44c0c95aa6539be927838
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rend
Externí odkaz:
https://doaj.org/article/c63732b2d27a4a86a9c0d7a20529368c
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/b547334243994244971a55f64bd83b9f
Autor:
Kern Rei Chng, Sock Hoai Chan, Amanda Hui Qi Ng, Chenhao Li, Apinya Jusakul, Denis Bertrand, Andreas Wilm, Su Pin Choo, Damien Meng Yew Tan, Kiat Hon Lim, Roy Soetinko, Choon Kiat Ong, Dan G. Duda, Simona Dima, Irinel Popescu, Chaisiri Wongkham, Zhu Feng, Khay Guan Yeoh, Bin Tean Teh, Puangrat Yongvanit, Sopit Wongkham, Vajaraphongsa Bhudhisawasdi, Narong Khuntikeo, Patrick Tan, Chawalit Pairojkul, Joanne Ngeow, Niranjan Nagarajan
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 195-202 (2016)
Cholangiocarcinoma (CCA) is the primary cancer of the bile duct system. The role of bile duct tissue microbiomes in CCA tumorigenesis is unestablished. To address this, sixty primary CCA tumors and matched normals, from both liver fluke (Opisthorchis
Externí odkaz:
https://doaj.org/article/c9842278ff3b4127801379be4266825f
Autor:
Arun Mouli Kolinjivadi, Siao Ting Chong, Ramveer Choudhary, Haresh Sankar, Ee Ling Chew, Claresta Yeo, Sock Hoai Chan, Joanne Ngeow
Publikováno v:
Human Molecular Genetics. 32:1401-1409
Monoallelic or biallelic RAD51C germline mutations results in chromosome instability disorders such as fanconi anemia (FA) and cancers. The bona fide function of RAD51C is to assist RAD51 nucleoprotein filament onto single strand DNA to complete Homo
Autor:
Zewen Zhang, Nur Diana Binte Ishak, Frances Victoria Fajardo Que, Zi Yang Chua, Sock Hoai Chan, Jianbang Chiang, Joanne Ngeow Yuen Yie
Background Although Singapore is one of the highest vaccinated countries in the world, vaccine hesitancy remains in a subpopulation, including individuals with cancer predisposition syndromes. At the Cancer Genetics Service National Cancer Centre Sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9adfb1c44bc6dfa0c52dff658610c7
https://doi.org/10.21203/rs.3.rs-1749535/v1
https://doi.org/10.21203/rs.3.rs-1749535/v1
Autor:
Sonia Davila, Sylvia Kam, Saumya Shekhar Jamuar, Khung Keong Yeo, Jyn Ling Kuan, Nicolas Bertin, Patrick Tan, Steve Rozen, Bin Tean Teh, Geoffrey S. Ginsburg, Jing Xian Teo, Cheng Xi Yang, Koei Wan Tham, Stuart A. Cook, Lori A. Orlando, Weng Khong Lim, Yasmin Bylstra, Sock Hoai Chan, R. Ryanne Wu
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Genome Medicine
Genome Medicine
Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rendering the
Autor:
Tze Hao Chia, Sock Hoai Chan, Siao Ting Chong, Tarryn Shaw, Jeanette Yuen, Ee Ling Chew, Joanne Ngeow, Nur Diana Binte Ishak, Jianbang Chiang, Shao-Tzu Li
Publikováno v:
JCO precision oncology. 5
PURPOSE Genetic testing has clinical utility in the management of patients with hereditary cancer syndromes. However, the increased likelihood of encountering a variant of uncertain significance in individuals of non-European descent such as Asians m